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Erschienen in: Zeitschrift für Gerontologie und Geriatrie 6/2017

01.08.2017 | Original Contribution

Prevalence of skin diseases in hospitalized geriatric patients

Association with gender, duration of hospitalization and geriatric assessment

verfasst von: Dr. med. E. Makrantonaki, E. Steinhagen-Thiessen, R. Nieczaj, C. C. Zouboulis, R. Eckardt

Erschienen in: Zeitschrift für Gerontologie und Geriatrie | Ausgabe 6/2017

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Abstract

Background

Improvement of quality of life in old age and prevention of age-associated diseases have become the main focus of research into aging; however, information regarding the skin health status of geriatric patients still remains sparse.

Goal

To investigate the extent of dermatological diseases in hospitalized geriatric patients, map the most prevalent ones, check for any gender differences and document any correlations with duration of hospitalization and results of geriatric assessments.

Patients and methods

A total of 110 hospitalized geriatric patients underwent a complete dermatological examination at the Evangelical Geriatric Hospital (Evangelisches Geriatriezentrum) Berlin. The collected information was stratified according to dermatological diagnosis, results of geriatric assessments, duration of hospitalization, age and gender of the patients.

Results

The average number of diagnosed skin diseases per patient was 3.7 ± 1.8 for the female population and 4.3 ± 2.0 for the male population. After categorizing all diagnosed skin diseases, infectious diseases were found to be most common in both female and male patients (55 % and 58 %, respectively) followed by vascular diseases (46.7 % and 54 %, respectively). Precancerous skin lesions and epithelial skin cancer were more frequent in men than in women (20 % vs. 6.7 %, p < 0.037 and 34 % vs. 13.3 %, p < 0.010, respectively). Pruritus showed a positive correlation with the duration of hospitalization and a negative correlation with the Barthel index and Tinetti score on the day of discharge, indicating that pruritus may have a significant impact on the physical condition of elderly multimorbid patients and on the static and dynamic balance abilities.

Conclusion

Our results demonstrate that skin health in the elderly is compromised and disregarded and this should constitute one of the top priorities of healthcare specialists and physicians in the future.

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Literatur
1.
Zurück zum Zitat American Geriatrics Society (2015) Updated beers criteria for potentially inappropriate medication use in older adults. By the american geriatrics society 2015 beers criteria update expert panel. J Am Geriatr Soc 63(11):2227–2246 CrossRef American Geriatrics Society (2015) Updated beers criteria for potentially inappropriate medication use in older adults. By the american geriatrics society 2015 beers criteria update expert panel. J Am Geriatr Soc 63(11):2227–2246 CrossRef
2.
Zurück zum Zitat Bertram L, Böckenhoff A, Demuth I, Düzel S, Eckardt R, Li SC, Lindenberger U, Pawelec G, Siedler T, Wagner GG, Steinhagen-Thiessen E (2014) Cohort profile: the Berlin aging study II (BASE-II). Int J Epidemiol 43(3):703–712 CrossRefPubMed Bertram L, Böckenhoff A, Demuth I, Düzel S, Eckardt R, Li SC, Lindenberger U, Pawelec G, Siedler T, Wagner GG, Steinhagen-Thiessen E (2014) Cohort profile: the Berlin aging study II (BASE-II). Int J Epidemiol 43(3):703–712 CrossRefPubMed
3.
Zurück zum Zitat Biagi E, Nylund L, Candela M, Ostan R, Bucci L, Pini E, Nikkïla J, Monti D, Satokari R, Franceschi C, Brigidi P, De Vos W (2010) Through ageing, and beyond: gut microbiota and inflammatory status in seniors and centenarians. PLoS One 17, 5(5):e10667 Biagi E, Nylund L, Candela M, Ostan R, Bucci L, Pini E, Nikkïla J, Monti D, Satokari R, Franceschi C, Brigidi P, De Vos W (2010) Through ageing, and beyond: gut microbiota and inflammatory status in seniors and centenarians. PLoS One 17, 5(5):e10667
4.
Zurück zum Zitat Braun-Falco O, Plewig G, Wolff H, Burgdorf W, Landthaler M (Hrsg) (2005) Dermatologie und Venerologie. Springer, Berlin, S 1431–1461 CrossRef Braun-Falco O, Plewig G, Wolff H, Burgdorf W, Landthaler M (Hrsg) (2005) Dermatologie und Venerologie. Springer, Berlin, S 1431–1461 CrossRef
5.
Zurück zum Zitat Charlesworth CJ, Smit E, Lee D, Alramadhan F, Odden MC (2015) Polypharmacy among adults aged 65 years and older in the united states: 1988–2010. J Gerontolog A Biol Sci Med Sci. doi: 10.1093/gerona/glv013 Charlesworth CJ, Smit E, Lee D, Alramadhan F, Odden MC (2015) Polypharmacy among adults aged 65 years and older in the united states: 1988–2010. J Gerontolog A Biol Sci Med Sci. doi: 10.1093/gerona/glv013
6.
Zurück zum Zitat Collin C, Wade D, Davies S, Horne V (1988) The barthel ADL index: a standard measure of disability. Int Disabil Stud 10:64–67 CrossRefPubMed Collin C, Wade D, Davies S, Horne V (1988) The barthel ADL index: a standard measure of disability. Int Disabil Stud 10:64–67 CrossRefPubMed
7.
Zurück zum Zitat Darjani A, Mohtasham-Amiri Z, Mohammad AK, Golchai J, Sadre-Eshkevari S, Alizade N (2013) Skin disorders among elder patients in a referral center in northern Iran. Dermatol Res Pract. doi: 10.1155/2013/193205 PubMedPubMedCentral Darjani A, Mohtasham-Amiri Z, Mohammad AK, Golchai J, Sadre-Eshkevari S, Alizade N (2013) Skin disorders among elder patients in a referral center in northern Iran. Dermatol Res Pract. doi: 10.1155/2013/193205 PubMedPubMedCentral
8.
Zurück zum Zitat Eckardt R, Steinhagen-Thiessen E, Kämpfe S, Buchmann N (2014) Polypharmacy and drug prescription in the elderly. Strategies for optimization. Z Gerontol Geriatr 47(4):293–301 CrossRefPubMed Eckardt R, Steinhagen-Thiessen E, Kämpfe S, Buchmann N (2014) Polypharmacy and drug prescription in the elderly. Strategies for optimization. Z Gerontol Geriatr 47(4):293–301 CrossRefPubMed
9.
Zurück zum Zitat Fabbri E, An Y, Zoli M, Simonsick EM, Guralnik JM, Bandinelli S, Boyd CM, Ferrucci L (2015) Aging and the burden of multimorbidity: associations with inflammatory and anabolic hormonal biomarkers. J Gerontol A Biol Sci Med Sci 70(1):63–70 CrossRefPubMed Fabbri E, An Y, Zoli M, Simonsick EM, Guralnik JM, Bandinelli S, Boyd CM, Ferrucci L (2015) Aging and the burden of multimorbidity: associations with inflammatory and anabolic hormonal biomarkers. J Gerontol A Biol Sci Med Sci 70(1):63–70 CrossRefPubMed
10.
Zurück zum Zitat Fang L, Teuchert M, Huber-Abel F, Schattauer D, Hendrich C, Dorst J, Zettlmeissel H, Wlaschek M, Scharffetter-Kochanek K, Kapfer T, Tumani H, Ludolph AC, Brettschneider J (2010) MMP-2 and MMP-9 are elevated in spinal cord and skin in a mouse model of ALS. J Neurol Sci 294:51–56 CrossRefPubMed Fang L, Teuchert M, Huber-Abel F, Schattauer D, Hendrich C, Dorst J, Zettlmeissel H, Wlaschek M, Scharffetter-Kochanek K, Kapfer T, Tumani H, Ludolph AC, Brettschneider J (2010) MMP-2 and MMP-9 are elevated in spinal cord and skin in a mouse model of ALS. J Neurol Sci 294:51–56 CrossRefPubMed
11.
Zurück zum Zitat Furue M, Yamazaki S, Jimbow K, Tsuchida T, Amagai M, Tanaka T, Matsunaga K, Muto M, Morita E, Akiyama M, Soma Y, Terui T, Manabe M (2011) Prevalence of dermatological disorders in Japan: a nationwide, cross-sectional, seasonal, multicenter, hospital-based study. J Dermatol 38:310–320 CrossRefPubMed Furue M, Yamazaki S, Jimbow K, Tsuchida T, Amagai M, Tanaka T, Matsunaga K, Muto M, Morita E, Akiyama M, Soma Y, Terui T, Manabe M (2011) Prevalence of dermatological disorders in Japan: a nationwide, cross-sectional, seasonal, multicenter, hospital-based study. J Dermatol 38:310–320 CrossRefPubMed
13.
Zurück zum Zitat Hofmann B, Adam AC, Jacobs K, Riemer M, Erbs C, Bushnaq H, Simm A, Silber RE, Santos AN (2013) Advanced glycation end product associated skin autofluorescence: a mirror of vascular function? Exp Gerontol 48(1):38–44 CrossRefPubMed Hofmann B, Adam AC, Jacobs K, Riemer M, Erbs C, Bushnaq H, Simm A, Silber RE, Santos AN (2013) Advanced glycation end product associated skin autofluorescence: a mirror of vascular function? Exp Gerontol 48(1):38–44 CrossRefPubMed
14.
Zurück zum Zitat Kim EK, Kim HO, Park YM, Park CJ, Yu DS, Lee JY (2013) Prevalence and risk factors of depression in geriatric patients with dermatological diseases. Ann Dermatol 25:278–284 CrossRefPubMedPubMedCentral Kim EK, Kim HO, Park YM, Park CJ, Yu DS, Lee JY (2013) Prevalence and risk factors of depression in geriatric patients with dermatological diseases. Ann Dermatol 25:278–284 CrossRefPubMedPubMedCentral
15.
Zurück zum Zitat Kratzsch D, Simon JC, Treudler R (2016) Adverse drug reactions in the elderly: What dermatologists should know. Hautarzt 67(2):125–131 CrossRefPubMed Kratzsch D, Simon JC, Treudler R (2016) Adverse drug reactions in the elderly: What dermatologists should know. Hautarzt 67(2):125–131 CrossRefPubMed
17.
Zurück zum Zitat Makrantonaki E, Brink TC, Zampeli V, Elewa RM, Mlody B, Hossini AM, Hermes B, Krause U, Knolle J, Abdallah M, Adjaye J, Zouboulis CC (2012) Identification of biomarkers of human skin ageing in both genders. Wnt signalling – a label of skin ageing? PLoS ONE 7:e50393 CrossRefPubMedPubMedCentral Makrantonaki E, Brink TC, Zampeli V, Elewa RM, Mlody B, Hossini AM, Hermes B, Krause U, Knolle J, Abdallah M, Adjaye J, Zouboulis CC (2012) Identification of biomarkers of human skin ageing in both genders. Wnt signalling – a label of skin ageing? PLoS ONE 7:e50393 CrossRefPubMedPubMedCentral
18.
Zurück zum Zitat Makrantonaki E, Liakou AI, Eckardt R, Zens M, Steinhagen-Thiessen E, Zouboulis CC (2012) Skin diseases in geriatric patients. Epidemiologic data. Hautarzt 63:938–946 CrossRefPubMed Makrantonaki E, Liakou AI, Eckardt R, Zens M, Steinhagen-Thiessen E, Zouboulis CC (2012) Skin diseases in geriatric patients. Epidemiologic data. Hautarzt 63:938–946 CrossRefPubMed
19.
Zurück zum Zitat Makrantonaki E, Schönknecht P, Hossini AM, Kaiser E, Katsouli MM, Adjaye J, Schröder J, Zouboulis CC (2010) Skin and brain age together: the role of hormones in the ageing process. Exp Gerontol 45:801–813 CrossRefPubMed Makrantonaki E, Schönknecht P, Hossini AM, Kaiser E, Katsouli MM, Adjaye J, Schröder J, Zouboulis CC (2010) Skin and brain age together: the role of hormones in the ageing process. Exp Gerontol 45:801–813 CrossRefPubMed
20.
Zurück zum Zitat Makrantonaki E, Zouboulis CC (2010) Pathomechanisms of endogenously aged skin. In: Farage MA, Miller KW, Maibach HI (Hrsg) Textbook of aging skin. Springer, Berlin Heidelberg, S 94–99 Makrantonaki E, Zouboulis CC (2010) Pathomechanisms of endogenously aged skin. In: Farage MA, Miller KW, Maibach HI (Hrsg) Textbook of aging skin. Springer, Berlin Heidelberg, S 94–99
21.
Zurück zum Zitat Matterne U, Apfelbacher C, Loerbroks A (2011) Prevalence, correlates and characteristics of chronic pruritus: a population-based cross-sectional study. Acta Derm Venereol 91:674–679 CrossRefPubMed Matterne U, Apfelbacher C, Loerbroks A (2011) Prevalence, correlates and characteristics of chronic pruritus: a population-based cross-sectional study. Acta Derm Venereol 91:674–679 CrossRefPubMed
22.
Zurück zum Zitat Mitchell AJ (2013) The Mini-Mental State Examination (MMSE): an update on its diagnostic validity for cognitive disorders. In: Larner J (Hrsg) Cognitive screening instruments a practical approach. Springer, Heidelberg, S 15–46 CrossRef Mitchell AJ (2013) The Mini-Mental State Examination (MMSE): an update on its diagnostic validity for cognitive disorders. In: Larner J (Hrsg) Cognitive screening instruments a practical approach. Springer, Heidelberg, S 15–46 CrossRef
23.
24.
Zurück zum Zitat Schäfer T, Merkl J, Klemm E, Wichmann HE, Ring J (2006) The epidemiology of nevi and signs of skin aging in the adult general population: results of the KORA-survey 2000. J Invest Dermatol 126(7):1490–1496 CrossRefPubMed Schäfer T, Merkl J, Klemm E, Wichmann HE, Ring J (2006) The epidemiology of nevi and signs of skin aging in the adult general population: results of the KORA-survey 2000. J Invest Dermatol 126(7):1490–1496 CrossRefPubMed
25.
Zurück zum Zitat Sieber CC (2007) The elderly patient – who is that? Internist (Berl) 48(11):11192–11194 CrossRef Sieber CC (2007) The elderly patient – who is that? Internist (Berl) 48(11):11192–11194 CrossRef
26.
Zurück zum Zitat Siena Rubegni P, Poggiali S, Nami N, Rubegni M, Fimiani M (2012) Skin diseases in geriatric patients: our experience from a public skin outpatient clinic in Siena. G Ital Dermatol Venereol 147:631–636 PubMed Siena Rubegni P, Poggiali S, Nami N, Rubegni M, Fimiani M (2012) Skin diseases in geriatric patients: our experience from a public skin outpatient clinic in Siena. G Ital Dermatol Venereol 147:631–636 PubMed
27.
Zurück zum Zitat Souissi A, Zeglaoui F, El Fekih N, Fazaa B, Zouari B, Kamoun MR (2006) Skin diseases in the elderly: a multicentre Tunisian study. Ann Dermatol Venereol 133:231–234 CrossRefPubMed Souissi A, Zeglaoui F, El Fekih N, Fazaa B, Zouari B, Kamoun MR (2006) Skin diseases in the elderly: a multicentre Tunisian study. Ann Dermatol Venereol 133:231–234 CrossRefPubMed
28.
Zurück zum Zitat Tinetti ME (1990) A simple procedure for general screening for functional disability in the elderly patients. Ann Intern Med 112:699–706 CrossRefPubMed Tinetti ME (1990) A simple procedure for general screening for functional disability in the elderly patients. Ann Intern Med 112:699–706 CrossRefPubMed
29.
Zurück zum Zitat Vierkötter A, Schikowski T, Sugiri D, Matsui MS, Krämer U, Krutmann J (2015) MMP-1 and -3 promoter variants are indicative of a common susceptibility for skin and lung aging: results from a cohort of elderly women (SALIA). J Invest Dermatol 135(5):1268–1274 CrossRefPubMed Vierkötter A, Schikowski T, Sugiri D, Matsui MS, Krämer U, Krutmann J (2015) MMP-1 and -3 promoter variants are indicative of a common susceptibility for skin and lung aging: results from a cohort of elderly women (SALIA). J Invest Dermatol 135(5):1268–1274 CrossRefPubMed
30.
Zurück zum Zitat Weisshaar E, Szepietowski JC, Darsow U, Misery L, Wallengren J, Mettang T, Gieler U, Lotti T, Lambert J, Maisel P, Streit M, Greaves MW, Carmichael AJ, Tschachler E, Ring J, Ständer S (2012) European guideline on chronic pruritus. Acta Derm Venereol 92:563–581 CrossRefPubMed Weisshaar E, Szepietowski JC, Darsow U, Misery L, Wallengren J, Mettang T, Gieler U, Lotti T, Lambert J, Maisel P, Streit M, Greaves MW, Carmichael AJ, Tschachler E, Ring J, Ständer S (2012) European guideline on chronic pruritus. Acta Derm Venereol 92:563–581 CrossRefPubMed
31.
Zurück zum Zitat Yesavage JA, Brink TL, Rose TL (1983) Development and validation of a geriatric depression scale: a preliminary report. J Psychiatr Res 7:37–49 Yesavage JA, Brink TL, Rose TL (1983) Development and validation of a geriatric depression scale: a preliminary report. J Psychiatr Res 7:37–49
Metadaten
Titel
Prevalence of skin diseases in hospitalized geriatric patients
Association with gender, duration of hospitalization and geriatric assessment
verfasst von
Dr. med. E. Makrantonaki
E. Steinhagen-Thiessen
R. Nieczaj
C. C. Zouboulis
R. Eckardt
Publikationsdatum
01.08.2017
Verlag
Springer Medizin
Erschienen in
Zeitschrift für Gerontologie und Geriatrie / Ausgabe 6/2017
Print ISSN: 0948-6704
Elektronische ISSN: 1435-1269
DOI
https://doi.org/10.1007/s00391-016-1084-3