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Erschienen in:

2016 | OriginalPaper | Buchkapitel

4. Trophoblasterkrankung

verfasst von : Paul Speiser, Nina Pecha

Erschienen in: Die Geburtshilfe

Verlag: Springer Berlin Heidelberg

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Zusammenfassung

Trophoblasterkrankungen gehören zur Gruppe schwangerschaftsassoziierter Neoplasien, die sich v. a. hinsichtlich ihrer Tendenz zur lokalen Invasion und Metastasierung unterscheiden:

benigne, komplette und partielle hydatiforme Mole (Mola hydatidosa); die Unterscheidung wird anhand morphologischer und histopathologischer Kriterien sowie aufgrund des Karyotyps getroffen;
destruierende invasive Mole;
Plazentabetttumor;
Chorionkarzinom (malignes Chorionepitheliom).

Die Behandlung sollte entsprechend den Prognosefaktoren individuell angepasst werden. Bei Patientinnen mit nicht metastasierter Erkrankung oder metastasierter Erkrankung mit geringem prognostischem Risiko erfolgt die Monotherapie mit Methotrexat oder Dactinomycin, ansonsten darüber hinaus besteht die Therapie aus Kürettage oder Hysterektomie.

Vorheriges Kapitel Extrauteringravidiät

Nächstes Kapitel Ungewollte Schwangerschaft

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Titel: Trophoblasterkrankung
verfasst von: Paul Speiser
Nina Pecha
Verlag: Springer Berlin Heidelberg
Buch: Die Geburtshilfe
Print ISBN: 978-3-662-45063-5

Electronic ISBN: 978-3-662-45064-2

Copyright-Jahr: 2016
DOI: https://doi.org/10.1007/978-3-662-45064-2_4

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Zusammenfassung

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