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Erschienen in:
Präimplantation, Implantation und Plazentation Kapitel lesen Erstes Kapitel lesen

2016 | OriginalPaper | Buchkapitel

28. Physiologie und Pathologie des Geburtsbeginns

verfasst von : Henning Schneider, Hanns Helmer, Peter Husslein

Erschienen in: Die Geburtshilfe

Verlag: Springer Berlin Heidelberg

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Zusammenfassung

Die Geburt ist ein natürliches Geschehen, das durch den fetomaternalen Grenzbereich gesteuert wird. Als Vorbereitung auf die Geburt kommt es neben einer Auflockerung der Zervix sowie dem Verlust der Reißfestigkeit der Eihäute zu einer Zunahme der Kontraktilität des Myometriums. Als Mediatoren kommen dem Neuropeptid CRH, den Steroidhormonen Östrogen und Glukokortikoid sowie Prostaglandinen und Proteasen besondere Bedeutung zu. Mütterlicher Stress, aszendierende oder systemische Infektionen sowie Blutungen in die Dezidua können eine frühzeitige Aktivierung der fetalen HH-NNR-Achse bewirken und durch eine vorzeitige Auslösung des Geburtsgeschehens zu einer Frühgeburt führen.
Einer spontanen Geburt als natürliches Geschehen stehen mehr oder weniger indizierte Interventionen zur Schwangerschaftsbeendigung gegenüber, die unter dem Begriff der Entbindung zusammengefasst werden.
Vorheriges Kapitel Alloimmunerkrankungen und Schwangerschaft
Nächstes Kapitel Normale Geburt
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Metadaten
Titel
Physiologie und Pathologie des Geburtsbeginns
verfasst von
Henning Schneider
Hanns Helmer
Peter Husslein
Copyright-Jahr
2016
Verlag
Springer Berlin Heidelberg
Buch
Die Geburtshilfe

Print ISBN: 978-3-662-45063-5

Electronic ISBN: 978-3-662-45064-2

Copyright-Jahr: 2016

DOI
https://doi.org/10.1007/978-3-662-45064-2_28