Leitlinien zur Diagnostik bei Patienten mit Demenz

 

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Zusammenfassung

Derzeit existiert kein vollständiges und valides System zur Diagnostik der Demenzen. Die Leitlinien des Berufsverbandes der Allgemeinärzte, der Canadian Medical Association und der European Federation of Medical Societies werden vorgestellt und diskutiert. Während die Feststellung des Vorliegens einer Demenz und die Abgrenzung einer Depression einfach sind, bestehen besondere Probleme in der Differenzialdiagnostik der Demenzen untereinander und in der Frühdiagnostik. Es erscheint erforderlich, die einzelnen Konsenskriterien aufeinander abzustimmen und Kriterien für die Differenzialdiagnose festzulegen. Liquoruntersuchungen und MR-Techniken erlauben in naher Zukunft möglicherweise eine positive Diagnose des M. Alzheimer.

Consensus Criteria on Diagnosis in Patients with Dementia

At present, there is no valid diagnostic system that can be used for the diagnosis of dementia and its underlying causes. The consensus criteria of the German Association of Medical Practicioners, the Canadian Medical Association and the European Federation of Medical Societies are described. While the detection of the presence of dementia and the differential diagnosis towards depression seem relatively easy, there are considerable difficulties in the differential diagnosis among the dementias and in early diagnosis. It is deemed necessary to relate the various diagnostic consensus criteria towards each other and establish consensus for differential diagnosis. CSF analysis and new MR techniques may allow a positive diagnosis of Alzheimer's disease in the near future.

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Prof. Dr. Claus-W. Wallesch

Klinik und Poliklinik für Neurologie der Otto-von-Guericke-Universität

Leipziger Straße 44

39120 Magdeburg