References
Aarnoudse ALHJ, Dieleman JP, Stricker BHC. Age-and gender-specific incidence of hospitalisation for digoxin intoxication. Drug Saf 2007; 30(5): 431–6
Schneeweiss S, Hasford J, Göttler M, et al. Admissions caused by adverse drug events to internal medicine and emergency departments in hospitals: a longitudinal population-based study. Eur J Clin Pharmacol 2002 Jul; 58(4): 285–91
Begaud B, Evreux JC, Jouglard J, et al. Imputation of the unexpected or toxic effects of drugs: actualization of the method used in France [in French]. Therapie 1985 Mar–Apr; 40(2): 111–8
Schmiedl S, Szymanski J, Rottenkolber M, et al. Analysis of hospital admissions associated with digitalis glycosides [in German]. Med Klin (Munich) 2007 Aug 15; 102(8): 603–11
Warren JL. McBean AM, Hass SL, et al. Hospitalizations with adverse events caused by digitalis therapy among elderly Medicare beneficiaries. Arch Intern Med 1994 Jul 11; 154(13): 1482–7
Kernan WN, Castellsague J, Perlman GD, et al. Incidence of hospitalization for digitalis toxicity among elderly Americans. Am J Med 1994 May; 96(5): 426–31
Eschenhagen T. Kardiaka. In: Schwabe U, Paffrath D, editors. Arzneiverordnungs-Report 2005. Berlin, Heidelberg, New York: Springer, 2006: 686–90
Roever C, Ferrante J, Gonzalez EC, et al. Comparing the toxicity of digoxin and digitoxin in a geriatric population: should an old drug be rediscovered? South Med J 2000 Feb; 93(2): 199–202
Hardman JG, Gilman AG, Limbird LE, editors. Goodman and Gilman’s the pharmacological basis of therapeutics. 9th ed. New York: McGraw Hill, 1995
Rathore SS, Wang Y, Krumholz HM. Sex-based differences in the effect of digoxin for the treatment of heart failure. N Engl J Med 2002 Oct 31; 347(18): 1403–11
Adams KF, Patterson JH, Gattis WA, et al. Relationship of serum digoxin concentration to mortality and morbidity in women in the digitalis investigation group trial. J Am Coll Cardiol 2005 Aug 2; 46(3): 497–504
Glaeske G, Janhsen K. GEK-Arzneimittel-Report 2006. Auswertungsergebnisse der GEK-Arzneimitteldaten aus den Jahren 2004 and 2005. Sankt Augustin: Asgard, 2006: 274–5
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The study commented on in this letter was supported by BfArM (Federal Institute for Drugs and Medical Devices, Fo2.1-68502-201). The authors have no conflicts of interest that are directly relevant to the content of this letter.
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Schmiedl, S., Szymanski, J., Rottenkolber, M. et al. Age- and Gender-Specific Incidence of Hospitalisation for Digoxin Intoxication. Drug-Safety 30, 1171–1173 (2007). https://doi.org/10.2165/00002018-200730120-00009
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DOI: https://doi.org/10.2165/00002018-200730120-00009