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Benzodiazepines in Geriatric Psychiatry

What Doctors Report and What Patients Actually Use

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Abstract

Objective

Exact information on drug use is important information at admittance to hospital departments. The aim of this study was to validate the information given in the referral regarding benzodiazepine use by analysis of serum samples.

Methods

A total of 241 patients were included at admittance to a geriatric psychiatry department. Information on use of benzodiazepines according to the referral was recorded, and serum samples were analysed for benzodiazepine drugs. The number of patients with incorrect information in the referral was calculated for each benzodiazepine.

Results

Information on benzodiazepine use was included in 60 % of patient referrals. However, serum analyses revealed the use of different or additional benzodiazepines compared with the referral information in 24 % of the patients. In 10 % of the patients, a benzodiazepine was detected despite no information on benzodiazepine use at all in the referral. For diazepam, 70 % of users were identified by serum analyses only, while this number was lower for the other benzodiazepines.

Conclusions

This study shows that benzodiazepine use is widespread in geriatric psychiatry, but that information about the use of these drugs is very often incorrect. This may have significant clinical consequences if symptoms caused by use or abrupt cessation of benzodiazepines are misinterpreted.

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Acknowledgments

There are no conflicts of interest for any of the authors. No funding was received for this study.

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Authors and Affiliations

  1. Department of Geriatric Psychiatry, Diakonhjemmet Hospital, Oslo, Norway

    Gudrun Høiseth, Kari Midtbø Kristiansen & Bernhard Lorentzen

  2. Center for Psychopharmacology, Diakonhjemmet Hospital, Forskningsveien 7, Pb 85 Vinderen, 0319, Oslo, Norway

    Gudrun Høiseth & Helge Refsum

  3. The Norwegian Medicines Agency, Oslo, Norway

    Kristin Kvande

  4. Department of Research & Development in Psychiatry, Akershus University Hospital and University of Oslo, Oslo, Norway

    Lars Tanum

Authors
  1. Gudrun Høiseth
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  2. Kari Midtbø Kristiansen
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  3. Kristin Kvande
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  4. Lars Tanum
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  5. Bernhard Lorentzen
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  6. Helge Refsum
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Correspondence to Gudrun Høiseth.

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Høiseth, G., Kristiansen, K.M., Kvande, K. et al. Benzodiazepines in Geriatric Psychiatry. Drugs Aging 30, 113–118 (2013). https://doi.org/10.1007/s40266-012-0045-9

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  • DOI: https://doi.org/10.1007/s40266-012-0045-9

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