References
Breukels MA, Spanjaard L, Sanders LAM, Rijkers GT (2001) Immunological characterization of conjugated Haemophilus influenzae type b vaccine failure in infants. Clin Infect Dis 32: 1700–1705
Guimaraes T, Cereda RF, Bianchin PJ, Nagao AT, Sampaio MC, Mendonca JS (2002) Antibody response to Haemophilus influenzae type b tetanus conjugate vaccine with two doses given at 3 and 5 months of age. Int J Infect Dis 6: 113–117
Heath PT, McVernon J (2002) The UK Hib vaccine experience. Arch Dis Child 86: 396–369
Heath PT, Booy R, Griffiths H, Clutterbeck E, Azzopardj HJ, Slack MPE, Fogarty J, Maloney AC, Moxon ER (2000) Clinical and immunological risk factors associated with Haemophilus influenzae type b conjugate vaccine failure in childhood. Clin Infect Dis 31: 973–980
Pallares DE, Figueroa JE, Densen P, Giclas PC, Marshall GS (1996) Invasive Haemophilus influenzae type b infection in a child with familial deficiency of the beta subunit of the eight component of complement. J Pediatr 128: 102–103
Robbins JB, Parke JC Jr, Schneerson R, Whisnant JK (1973) Quantitative measurement of the ‘natural’ and immunization-induced Haemophilus influenzae type b capsular polysaccharide antibodies. Pediatr Res 7: 103–110
Acknowledgements
We thank Prof. Bartmann, Bonn, for determining Hib antibody levels and Prof. Schmitt, Mainz, for Haemophilus influenzae sero- and biotyping.
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Krueger, M., Fluegge, K., Krause, M.F. et al. Fatal Haemophilus influenzae type b sepsis in a 10-month-old infant despite complete vaccination and adequate Hib antibodies. Eur J Pediatr 163, 412–413 (2004). https://doi.org/10.1007/s00431-004-1449-2
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DOI: https://doi.org/10.1007/s00431-004-1449-2