Skip to main content
Log in

Classification and diagnosis of acute isolated syndesmotic injuries: ESSKA-AFAS consensus and guidelines

  • Ankle
  • Published:
Knee Surgery, Sports Traumatology, Arthroscopy Aims and scope

Abstract

Purpose

The aim of the present study was to perform a systematic review of the current classification systems, and the clinical and radiological tests for the acute isolated syndesmotic injuries to identify the best method of classification and diagnosis allowing the surgeon to choose the appropriate management.

Methods

A systematic review of the literature according to the PRISMA guidelines has been performed. A comprehensive search using various combinations of the keywords “classification”, “grading system”, “ankle injury”, “ligament”, “syndesmotic injury”, “internal fixation”, “acute”, “synostosis”, “ligamentoplasties”, “clinical”, “radiological” over the years 1962–2015 was performed. The following databases were searched: MEDLINE, Google Scholar, EMBASE and Ovid.

Results

The literature search resulted in 345 references for classification systems and 308 references for diagnosis methods, of which 283 and 295 were rejected due to off-topic abstract and/or failure to fulfil the inclusion criteria. After reading the remaining full-text articles, we included 27 articles describing classification systems and 13 articles describing diagnostic tests for acute isolated syndesmotic injuries.

Conclusions

The ESSKA-AFAS consensus panel recommends distinguishing acute isolated syndesmotic injury as stable or unstable. Stable injuries should be treated non-operatively with a short-leg cast or brace, while unstable injuries should be managed operatively. The recommended clinical tests include: tenderness on palpation over the anterior tibiofibular ligament, the fibular translation test and the Cotton test. Radiographic imaging must include an AP view and a mortise view of the syndesmosis to check the tibiofibular clear space, medial clear space overlap, tibial width and fibular width.

Level of evidence

IV.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1
Fig. 2

Similar content being viewed by others

References

  1. Ahmad CS, Redler LH, Ciccotti MG, Maffulli N, Longo UG, Bradley J (2013) Evaluation and management of hamstring injuries. Am J Sports Med 41(12):2933–2947

    Article  PubMed  Google Scholar 

  2. Alonso A, Khoury L, Adams R (1998) Clinical tests for ankle syndesmosis injury: reliability and prediction of return to function. J Orthop Sports Phys Ther 27(4):276–284

    Article  CAS  PubMed  Google Scholar 

  3. Amendola A (1992) Controversies in diagnosis and management of syndesmosis injuries of the ankle. Foot Ankle 13(1):44–50

    Article  CAS  PubMed  Google Scholar 

  4. Amendola A, Williams G, Foster D (2006) Evidence-based approach to treatment of acute traumatic syndesmosis (high ankle) sprains. Sports Med Arthrosc 14(4):232–236

    Article  PubMed  Google Scholar 

  5. Beumer A (2007) Chronic instability of the anterior syndesmosis of the ankle. Acta Orthop Suppl 78(327):4–36

    PubMed  Google Scholar 

  6. Beumer A, Swierstra BA, Mulder PG (2002) Clinical diagnosis of syndesmotic ankle instability: evaluation of stress tests behind the curtains. Acta Orthop Scand 73(6):667–669

    PubMed  Google Scholar 

  7. Beumer A, Valstar ER, Garling EH, Niesing R, Ginai AZ, Ranstam J, Swierstra BA (2006) Effects of ligament sectioning on the kinematics of the distal tibiofibular syndesmosis: a radiostereometric study of 10 cadaveric specimens based on presumed trauma mechanisms with suggestions for treatment. Acta Orthop 77(3):531–540

    Article  PubMed  Google Scholar 

  8. Beumer A, Valstar ER, Garling EH, Niesing R, Heijboer RP, Ranstam J, Swierstra BA (2005) Kinematics before and after reconstruction of the anterior syndesmosis of the ankle: a prospective radiostereometric and clinical study in 5 patients. Acta Orthop 76(5):713–720

    Article  PubMed  Google Scholar 

  9. Bonnin JG (1965) Injury to the ligaments of the ankle. J Bone Joint Surg Br 47(4):609–611

    CAS  PubMed  Google Scholar 

  10. Boytim MJ, Fischer DA, Neumann L (1991) Syndesmotic ankle sprains. Am J Sports Med 19(3):294–298

    Article  CAS  PubMed  Google Scholar 

  11. Bozic KJ, Jaramillo D, DiCanzio J, Zurakowski D, Kasser JR (1999) Radiographic appearance of the normal distal tibiofibular syndesmosis in children. J Pediatr Orthop 19(1):14–21

    CAS  PubMed  Google Scholar 

  12. Brown KW, Morrison WB, Schweitzer ME, Parellada JA, Nothnagel H (2004) MRI findings associated with distal tibiofibular syndesmosis injury. Am J Roentgenol 182(1):131–136

    Article  Google Scholar 

  13. Close JR (1956) Some applications of the functional anatomy of the ankle joint. J Bone Joint Surg Am 38(4):761–781

    PubMed  Google Scholar 

  14. de Cesar PC, Avila EM, de Abreu MR (2011) Comparison of magnetic resonance imaging to physical examination for syndesmotic injury after lateral ankle sprain. Foot Ankle Int 32(12):1110–1114

    Article  PubMed  Google Scholar 

  15. Del Buono A, Florio A, Boccanera MS, Maffulli N (2013) Syndesmosis injuries of the ankle. Curr Rev Musculoskelet Med 6(4):313–319

    Article  PubMed  PubMed Central  Google Scholar 

  16. Ebraheim NA, Taser F, Shafiq Q, Yeasting RA (2006) Anatomical evaluation and clinical importance of the tibiofibular syndesmosis ligaments. Surg Radiol Anat 28(2):142–149

    Article  PubMed  Google Scholar 

  17. Edwards GS Jr, DeLee JC (1984) Ankle diastasis without fracture. Foot Ankle 4(6):305–312

    Article  PubMed  Google Scholar 

  18. Endean T, King W, Martin HR (2003) Syndesmotic rupture without ankle fracture. A report of two cases in professional football players. J Am Podiatr Med Assoc 93(4):336–339

    Article  PubMed  Google Scholar 

  19. Espinosa N, Smerek JP, Myerson MS (2006) Acute and chronic syndesmosis injuries: pathomechanisms, diagnosis and management. Foot Ankle Clin 11(3):639–657

    Article  PubMed  Google Scholar 

  20. Gerber JP, Williams GN, Scoville CR, Arciero RA, Taylor DC (1998) Persistent disability associated with ankle sprains: a prospective examination of an athletic population. Foot Ankle Int 19(10):653–660

    Article  CAS  PubMed  Google Scholar 

  21. Han SH, Lee JW, Kim S, Suh JS, Choi YR (2007) Chronic tibiofibular syndesmosis injury: the diagnostic efficiency of magnetic resonance imaging and comparative analysis of operative treatment. Foot Ankle Int 28(3):336–342

    Article  PubMed  Google Scholar 

  22. Harper MC (1993) An anatomic and radiographic investigation of the tibiofibular clear space. Foot Ankle 14(8):455–458

    Article  CAS  PubMed  Google Scholar 

  23. Hopkinson WJ, St Pierre P, Ryan JB, Wheeler JH (1990) Syndesmosis sprains of the ankle. Foot Ankle 10(6):325–330

    Article  CAS  PubMed  Google Scholar 

  24. Kim S, Huh YM, Song HT, Lee SA, Lee JW, Lee JE, Chung IH, Suh JS (2007) Chronic tibiofibular syndesmosis injury of ankle: evaluation with contrast-enhanced fat-suppressed 3D fast spoiled gradient-recalled acquisition in the steady state MR imaging. Radiology 242(1):225–235

    Article  PubMed  Google Scholar 

  25. Liberati A, Altman DG, Tetzlaff J, Mulrow C, Gotzsche PC, Ioannidis JP, Clarke M, Devereaux PJ, Kleijnen J, Moher D (2009) The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate healthcare interventions: explanation and elaboration. BMJ 339:b2700

    Article  PubMed  PubMed Central  Google Scholar 

  26. Lin C-F (2006) Ankle syndesmosis injuries: anatomy, biomechanics, mechanism of injury, and clinical guidelines for diagnosis and intervention. J Orthop Sports Phys Ther 36(6):372–384

    Article  PubMed  Google Scholar 

  27. Lindenfeld T, Parikh S (2005) Clinical tip: heel-thump test for syndesmotic ankle sprain. Foot Ankle Int 26(5):406–408

    PubMed  Google Scholar 

  28. Longo UG, Loppini M, Berton A, Marinozzi A, Maffulli N, Denaro V (2012) The FIFA 11 + program is effective in preventing injuries in elite male basketball players: a cluster randomized controlled trial. Am J Sports Med 40(5):996–1005

    Article  PubMed  Google Scholar 

  29. Maffulli N, Longo UG, Gougoulias N, Caine D, Denaro V (2011) Sport injuries: a review of outcomes. Br Med Bull 97:47–80

    Article  PubMed  Google Scholar 

  30. Maffulli N, Longo UG, Gougoulias N, Loppini M, Denaro V (2010) Long-term health outcomes of youth sports injuries. Br J Sports Med 44(1):21–25

    Article  CAS  PubMed  Google Scholar 

  31. Maffulli N, Longo UG, Spiezia F, Denaro V (2011) Aetiology and prevention of injuries in elite young athletes. Med Sport Sci 56:187–200

    Article  PubMed  Google Scholar 

  32. Magan A, Golano P, Maffulli N, Khanduja V (2014) Evaluation and management of injuries of the tibiofibular syndesmosis. Br Med Bull 111(1):101–115

    Article  PubMed  Google Scholar 

  33. Marymont JV, Lynch MA, Henning CE (1986) Acute ligamentous diastasis of the ankle without fracture. Evaluation by radionuclide imaging. Am J Sports Med 14(5):407–409

    Article  CAS  PubMed  Google Scholar 

  34. Massobrio M, Antonietti G, Albanese P, Necci F (2011) Operative treatment of tibiofibular diastasis: a comparative study between transfixation screw and reabsorbable cerclage. Preliminary result. Clin Ter 162(6):e161–e167

    CAS  PubMed  Google Scholar 

  35. McCollum GA, van den Bekerom MP, Kerkhoffs GM, Calder JD, van Dijk CN (2013) Syndesmosis and deltoid ligament injuries in the athlete. Knee Surg Sports Traumatol Arthrosc 21(6):1328–1337

    Article  PubMed  Google Scholar 

  36. Mei-Dan O, Kots E, Barchilon V, Massarwe S, Nyska M, Mann G (2009) A dynamic ultrasound examination for the diagnosis of ankle syndesmotic injury in professional athletes: a preliminary study. Am J Sports Med 37(5):1009–1016

    Article  PubMed  Google Scholar 

  37. Miller CD, Shelton WR, Barrett GR, Savoie FH, Dukes AD (1995) Deltoid and syndesmosis ligament injury of the ankle without fracture. Am J Sports Med 23(6):746–750

    Article  CAS  PubMed  Google Scholar 

  38. Miller TL, Skalak T (2014) Evaluation and treatment recommendations for acute injuries to the ankle syndesmosis without associated fracture. Sports Med 44(2):179–188

    Article  PubMed  Google Scholar 

  39. Milz P, Milz S, Steinborn M, Mittlmeier T, Putz R, Reiser M (1998) Lateral ankle ligaments and tibiofibular syndesmosis. 13-MHz high-frequency sonography and MRI compared in 20 patients. Acta Orthop Scand 69(1):51–55

    Article  CAS  PubMed  Google Scholar 

  40. Morris MW, Rice P, Schneider TE (2009) Distal tibiofibular syndesmosis reconstruction using a free hamstring autograft. Foot Ankle Int 30(6):506–511

    Article  PubMed  Google Scholar 

  41. Mulligan EP (2011) Evaluation and management of ankle syndesmosis injuries. Phys Ther Sports 12(2):57–69

    Article  Google Scholar 

  42. Nussbaum ED, Hosea TM, Sieler SD, Incremona BR, Kessler DE (2001) Prospective evaluation of syndesmotic ankle sprains without diastasis. Am J Sports Med 29(1):31–35

    CAS  PubMed  Google Scholar 

  43. Oae K, Takao M, Naito K, Uchio Y, Kono T, Ishida J, Ochi M (2003) Injury of the tibiofibular syndesmosis: value of MR imaging for diagnosis. Radiology 227(1):155–161

    Article  PubMed  Google Scholar 

  44. Ogilvie-Harris DJ, Reed SC (1994) Disruption of the ankle syndesmosis: diagnosis and treatment by arthroscopic surgery. Arthroscopy 10(5):561–568

    Article  CAS  PubMed  Google Scholar 

  45. Ogilvie-Harris DJ, Reed SC, Hedman TP (1994) Disruption of the ankle syndesmosis: biomechanical study of the ligamentous restraints. Arthroscopy 10(5):558–560

    Article  CAS  PubMed  Google Scholar 

  46. Porter DA (2009) Evaluation and treatment of ankle syndesmosis injuries. Instr Course Lect 58:575–581

    PubMed  Google Scholar 

  47. Porter DA, May BD, Berney T (2008) Functional outcome after operative treatment for ankle fractures in young athletes: a retrospective case series. Foot Ankle Int 29(9):887–894

    Article  PubMed  Google Scholar 

  48. Porter DA, Jaggers RR, Barnes AF, Rund AM (2014) Optimal management of ankle syndesmosis injuries. Open Access J Sports Med 5:173–182

    Article  PubMed  PubMed Central  Google Scholar 

  49. Press CM, Gupta A, Hutchinson MR (2009) Management of ankle syndesmosis injuries in the athlete. Curr Sports Med Rep 8(5):228–233

    Article  PubMed  Google Scholar 

  50. Rammelt S, Zwipp H, Grass R (2008) Injuries to the distal tibiofibular syndesmosis: an evidence-based approach to acute and chronic lesions. Foot Ankle Clin 13(4):611–633

    Article  PubMed  Google Scholar 

  51. Scranton PE, McDermott JE, Rogers JV (2000) The relationship between chronic ankle instability and variations in mortise anatomy and impingement spurs. Foot Ankle Int 21(8):657–664

    PubMed  Google Scholar 

  52. Sikka RS, Fetzer GB, Sugarman E, Wright RW, Fritts H, Boyd JL, Fischer DA (2012) Correlating MRI findings with disability in syndesmotic sprains of NFL players. Foot Ankle Int 33(5):371–378

    Article  PubMed  Google Scholar 

  53. Smith KM, Kovacich-Smith KJ, Witt M (2001) Evaluation and management of high ankle sprains. Clin Podiatr Med Surg 18(3):443–456

    CAS  PubMed  Google Scholar 

  54. Takao M, Ochi M, Oae K, Naito K, Uchio Y (2003) Diagnosis of a tear of the tibiofibular syndesmosis. The role of arthroscopy of the ankle. J Bone Joint Surg Br 85(3):324–329

    Article  CAS  PubMed  Google Scholar 

  55. Taylor DC, Tenuta JJ, Uhorchak JM, Arciero RA (2007) Aggressive surgical treatment and early return to sports in athletes with grade III syndesmosis sprains. Am J Sports Med 35(11):1833–1838

    Article  PubMed  Google Scholar 

  56. Valkering KP, Vergroesen DA, Nolte PA (2012) Isolated syndesmosis ankle injury. Orthopedics 35(12):e1705–e1710

    Article  PubMed  Google Scholar 

  57. van den Bekerom MP, Raven EE (2009) Arthrex tightrope distal tibiofibular syndesmotic stabilization. Foot Ankle Int 30(6):577–578

    Article  PubMed  Google Scholar 

  58. Ward DW (1994) Syndesmotic ankle sprain in a recreational hockey player. J Manipulative Physiol Ther 17(6):385–394

    CAS  PubMed  Google Scholar 

  59. Xenos JS, Hopkinson WJ, Mulligan ME, Olson EJ, Popovic NA (1995) The tibiofibular syndesmosis. Evaluation of the ligamentous structures, methods of fixation, and radiographic assessment. J Bone Joint Surg Am 77(6):847–856

    CAS  PubMed  Google Scholar 

  60. Zalavras C, Thordarson D (2007) Ankle syndesmotic injury. J Am Acad Orthop Surg 15(6):330–339

    Article  PubMed  Google Scholar 

  61. Zamzami MM, Zamzam MM (2009) Chronic isolated distal tibiofibular syndesmotic disruption: diagnosis and management. Foot Ankle Surg 15(1):14–19

    Article  PubMed  Google Scholar 

  62. Zwipp H, Rammelt S, Grass R (2002) Ligamentous injuries about the ankle and subtalar joints. Clin Podiatr Med Surg 19(2):195–229

    Article  PubMed  Google Scholar 

Download references

Acknowledgments

We would like to thank the following members of the ESSKA-AFAS consensus committee for their contribution: Gino Kerkhoffs, James Calder, John Kennedy, Akos Kynsburg, Tahir Ogut, Beat Hintermann, Milan Handl, Pietro Spennacchio.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Umile Giuseppe Longo.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

van Dijk, C.N., Longo, U.G., Loppini, M. et al. Classification and diagnosis of acute isolated syndesmotic injuries: ESSKA-AFAS consensus and guidelines. Knee Surg Sports Traumatol Arthrosc 24, 1200–1216 (2016). https://doi.org/10.1007/s00167-015-3942-8

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00167-015-3942-8

Keywords

Navigation