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Synkope und epileptischer Anfall

  • Schwerpunkt: Internistische Notfallmedizin
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Zusammenfassung

Die Synkope ist eines der häufigsten Symptome, welche zur stationären Einweisung führen. Dabei können verschiedenste Grunderkrankungen Ursache der Synkope sein. Entscheidend ist das Erkennen von zugrundliegenden strukturellen Herzerkrankungen und Rhythmusstörungen, da diese mit einer deutlich erhöhten Letalität einhergehen. Entscheidende Hinweise auf die Genese der Synkope gibt die sorgfältige Anamnese; ergänzende Untersuchungen sollten nur gezielt eingesetzt werden. Bei Nachweis einer strukturellen Herzerkrankung ist die Therapie der Grunderkrankung einzuleiten, bei Nachweis einer rhythmogen Synkopen kann die Therapie mit Schrittmacher, implantierbarem Kardioverter-Defibrillator oder Antiarrhythmika indiziert sein. Bei den häufigen neurogenen und orthostatischen Synkopen führt in erster Linie der Einsatz tonisierender körperlicher Übungen zum Erfolg. Neben Synkopen ist bei temporärer Bewusstseinsstörung auch an einen epileptischen Anfall zu denken. Bei der Differenzierung ist dabei vor allem die Fremdanamnese zum Verlauf der Synkope von Bedeutung.

Abstract

Syncope is one of the most common symptoms leading to hospital admission. Thereby syncope can be induced by several diseases. It is crucial to detect underlying structural heart disease or high grade arrhythmias, as these are associated with an increased mortality. The careful history and physical examination can often give sufficient evidence to evaluate the origin of syncope. Additional examinations should only be applied selectively. In patients with structural heart disease the specific treatment should be initiated, in patients with cardiac arrhythmias the implantation of a pacemaker or ICD might be indicated. The most common neurally-mediated and orthostatic syncopes can often be treated successfully by physical training. Beside syncope epilepsy might be responsible for a transient loss of consciousness. Again careful history taking helps to differentiate between these two entities.

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Literatur

  1. Alboni P, Brignole M, Menozzi C et al. (2001) The diagnostic value of history in patients with syncope with or without heart disease. J Am Coll Cardiol 37: 1921–1928

    Article  PubMed  Google Scholar 

  2. Bartoletti A, Gaggioli G, Bottoni N et al. (1999) Head-up tilt testing potentiated with oral nitroglycerin. A randomized trial of the contribution of a drug-free phase and a nitroglycerin phase in the diagnosis of neurally mediated syncope. Europace 1: 183–186

    Article  PubMed  Google Scholar 

  3. Brignole M, Alboni P, Benditt D et al. Task Force on Syncope (2001) Guidelines on management (diagnosis and treatment) of syncope. Eur Heart J 22: 1256–1306

    Article  PubMed  Google Scholar 

  4. Brignole M, Menozzi C, Gianfranchi L et al. (1992) A controlled trial of acute and long-term medical therapy in tilt-induced neurally mediated syncope. Am J Cardiol 70: 339–342

    Article  PubMed  Google Scholar 

  5. Brignole M, Sartore B, Prato R (1983) Role of body position during carotid sinus stimulation test in the diagnosis of cardioinhibitory carotid sinus syndrome. G Ital Cardiol 14: 69–72

    Google Scholar 

  6. Connolly SJ, Sheldon R, Roberts RS et al. (1999) Vasovagal pacemaker study investigators. The North American vasovagal pacemaker study (VPS): A randomized trial of permanent cardiac pacing for the prevention of vasovagal syncope. J Am Coll Cardiol 33: 16–20

    Article  PubMed  Google Scholar 

  7. Del Rosso A, Bartoli P, Bartoletti A et al. (1998) Shortened head-up tilt testing potentiated with sublingual nitroglycerin in patients with unexplained syncope. Am Heart J 135: 564–570

    PubMed  Google Scholar 

  8. Dhingra RC, Wyndham C, Bauernfeind R et al. (1979) Significance of block distal to the His bundle induced by atrial pacing in patients with chronic bifascicular block. Circulation 60: 1455–1464

    PubMed  Google Scholar 

  9. Franke H (1963) Ueber das Karotissinus-Syndrom und den sogenannten hyperactiven Karotissinus-Reflex. Fridrich-Kave Schattauer, Stuttgart

  10. Gibson TC, Heitzmann MR (1984) Diagnostic efficacy of 24-hour electrocardiographic monitoring for syncope. Am J Cardiol 53: 1013–1017

    Article  PubMed  Google Scholar 

  11. Gregoratos G, Abrams J, Epstein AE et al. (2002) ACC/AHA/NASPE 2002 guideline update for implantation of cardiac pacemakers and antiarrhythmia devices: summary article. A report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (ACC/AHA/NASPE Committee to Update the 1998 Pacemaker Guidelines). J Cardiovasc Electrophysiol 13: 1183–1199

    Google Scholar 

  12. Hainsworth R (1999) Syncope and fainting: classification and pathophysiological basis. In: Mathias CJ, Bannister R (eds) Autonomic failure. A textbook of clinical disorders of the autonomic nervous system, 4th edn. Oxford University Press, pp 428–36

  13. Hoefnagels WAJ, Padberg GW, Overweg J et al. (1991) Transient loss of consciousness: the value of the history for distinguishing seizure from syncope. J Neurol 238: 39–43

    Article  PubMed  Google Scholar 

  14. Krahn A, Klein GJ, Yee R et al. (1998) Final results from a pilot study with an implantable loop recorder to determine the etiology of syncope in patients with negative noninvasive and invasive testing. Am J Cardiol 82: 117–119

    Article  PubMed  Google Scholar 

  15. Lempert T, Bauer M, Schmidt D (1994) Syncope: a videometric analysis of 56 episodes of transient cerebral hypoxia. Ann Neurol 36: 233–237

    Article  PubMed  Google Scholar 

  16. Lenk M, Alehan, Ozme S et al. (1997) The role of serotonin re-uptake inhibitors in preventing recurrent unexplained childhood syncope – a preliminary report. Eur J Pediat 156: 747–750

    Article  Google Scholar 

  17. Linzer M, Pritchett ELC, Pontinen M et al. (1990) Incremental diagnostic yield of loop electrocardiographic recorders in unexplained syncope. Am J Cardiol 66: 214–219

    Article  PubMed  Google Scholar 

  18. Madigan NP, Flaker GC, Curtis JJ et al. (1984) Carotid sinus hypersensitivity: Beneficial effects of dual-chamber pacing. Am J Cardiol 53: 1034–1040

    Article  PubMed  Google Scholar 

  19. Martin GJ, Adams SL, Martin HG et al. (1984) Prospective evaluation of syncope. Ann Emerg Med 13: 499–504

    PubMed  Google Scholar 

  20. Menozzi C, Brignole M, Alboni P et al. (1998) The natural course of untreated sick sinus syndrome and identification of the variables predictive of unfavourable outcome. Am J Cardiol 82: 1205–1209

    Article  PubMed  Google Scholar 

  21. Middlekauff H, Stevenson W, Stevenson L et al. (1993) Syncope in advanced heart failure: high risk of sudden death regardless of origin of syncope. J Am Coll Cardiol 21: 110–116

    PubMed  Google Scholar 

  22. Mittal S, Iwai S, Stein K et al. (1999) Long-term outcome of patients with unexplained syncope treated with an electrophysiologic-guided approach in the implantable cardioverter-defibirillator era. J Am Coll Cardiol 34: 1082–1089

    Article  PubMed  Google Scholar 

  23. Mtinangi B, Hainsworth R (1998) Increased orthostatic tolerance following moderate exercise training in patients with unexplained syncope. Heart 80: 596–600

    PubMed  Google Scholar 

  24. Panther R, Mahmood S, Gal R.(1998) Echocardiography in the diagnostic evaluation of syncope. J Am Soc Echocardiogr 11: 294–298

    PubMed  Google Scholar 

  25. Recchia D, Barzilai B (1995) Echocardiography in the evaluation of patients with syncope. J Gen Intern Med 10: 649–655

    PubMed  Google Scholar 

  26. Raviele SA, Menozzi C, Brignole M et al. (1995) Value of head-up tilt testing potentiated with sublingual nitroglycerin to assess the origin of unexplained syncope. Am J Cardiol 76: 267–272

    Article  PubMed  Google Scholar 

  27. Rossen R, Kabat H, Anderson JP (1943) Acute arrest of cerebral circulation in man. Arch Neurol Psychiatr 50: 510–528

    Google Scholar 

  28. Sheldon R, Rose S, Flanagan P et al. (1996) Effects of beta blockers on the time to first syncope recurrence in patients after a positive isoproterenol tilt table test. Am J Cardiol 78: 536–539

    Article  PubMed  Google Scholar 

  29. Smit AAJ, Halliwill JR, Low PA, Wieling W (1999) Topical review. Pathophysiological basis of orthostatic hypotension in autonomic failure. J Physiol 519: 1–10

    Article  PubMed  Google Scholar 

  30. Ward CR, Gray JC, Gilroy JJ et al. (1998) Midodrine: a role in the management of neurocardiogenic syncope. Heart 79: 45–49

    PubMed  Google Scholar 

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Becker, A., Noachtar, S., Reithmann, C. et al. Synkope und epileptischer Anfall. Internist 46, 994–1005 (2005). https://doi.org/10.1007/s00108-005-1475-9

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  • DOI: https://doi.org/10.1007/s00108-005-1475-9

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