Zusammenfassung
Die akute Cholezystitis ist die häufigste Komplikation der Cholezystolithiasis und zählt mit gut 64.000 stationär behandelten Patienten pro Jahr zu den relevanten chirurgischen Krankheitsbildern. Sie kann mild verlaufen, aber auch lebensbedrohliche Formen annehmen, wovon v. a. alte und vorerkrankte Patienten betroffen sind. Eine Komplikationsform ist die Gallenblasenperforation, die überwiegend erst intraoperativ augenscheinlich wird. Als klassische Trias der akuten Cholezystitis können plötzlich einsetzender Oberbauchschmerz, Fieber und Leukozytose bezeichnet werden. Der klinische Verdacht lässt sich meist durch eine Sonographie bestätigen.
Abstract
Acute cholecystitis is the most common complication of cholecystolithiasis. With some 64,000 patients per year requiring surgical inpatient treatment it remains a prevalent surgical disease. The presentation varies between mild, severe and life-threatening forms and predominantly in old and morbid patients. Gallbladder perforation is a possible complication which is often only diagnosed during surgery. Typical clinical symptoms are pain in the upper abdomen, fever and leucocytosis. Ultrasonography may often be used to confirm the clinical diagnosis.
Literatur
Ahmed A, Cheung RC, Keeffe EB (2000) Management of gallstones and their complications. Am Fam Physician 61:1673–1680, 1687–1688
Bedirli A, Sakrak O, Sozuer EM et al (2001) Factors effecting the complications in the natural history of acute cholecystitis. Hepatogastroenterology 48:1275–1278
Berk und Monroe (1976) Gallenwegschirurgie: Indikationen und Operative Verfahren bei Gutartigen Gallenwegserkrankungen, S 1086–1091
Browning JD, Horton JD (2003) Gallstone disease and its complications. Semin Gastrointest Dis 14:165–177
BQS Bundesgeschäftsstelle Qualitätssicherung gGmbH.Qualität sichtbar machen. BQS-Qualitätsreport 2001. ISBN 3–9808704-2–1 Düsseldorf 2002
Chen YT, Ou SM, Chao PW et al (2012) Acute cholecystitis in end-stage renal disease patients: a nation-wide longitudinal study. Dig Liver Dis:1590–8658 ((12)00333–7 (Epub ahead of print))
Chen JJ, Lin HH, Chiu CT, Lin DY (1990) Gallbladder perforation with intrahepatic abscess formation. J Clin Ultrasound 18:43–45
Chiapponi C, Wirth S, Siebeck M (2010) Acute gallbladder perforation with gallstones spillage in a cirrhotic patient. World J Emerg Surg 5:11–14
Chloptsios C, Karanasiou V, Ilias G et al (2007) Cholecystitis during pregnancy. A case report and brief review of the literature. Clin Exp Obstet Gynecol 34:250–251
Date RS, Thrumurthy SG, Whiteside S et al (2012) Gallbladder perforation: case series and systematic review. Int J Surg 10:63–68
Derici H, Kamer E, Kara C et al (2010) Gallbladder perforation: clinical presentation, predisposing factors, and surgical outcomes of 46 patients. Turk J Gastroenterol 22:505–512
Derici H, Kara C, Bozdag AD et al (2006) Diagnosis and treatment of gallbladder perforation. World J Gastroenterol 12:7832–7836
Fabian TC, Hickerson WL, Mangiante EC (1986) Posttraumatic and postoperative acute cholecystitis. Am Surg 52:188–192
Eskelinen M, Ikonen J, Lipponen P (1993) Diagnostic approaches in acute cholecystitis; a prospective study of 1333 patients with acute abdominal pain. Theor Surg 8:15–20
Estevao-Costa J, Soares-Oliveira M, Lopes JM, Carvalho JL (2002) Idiopathic perforation of the gallbladder: a novel differential diagnosis of acute abdomen. J Pediatr Gastroenterol Nutr 35:88–89
Gurusamy KS, Samraj K (2006) Early versus delayed laparoscopic cholecystectomy for acute cholecystitis. Cochrane Database Syst Rev 4:CD005440
Gore RM, Ghahremani GG, Joseph AE et al (1989) Acquired malposition of the colon and gallbladder in patients with cirrhosis: CT findings and clinical implications. Radiology 171:739–742
Grande M, Torquati A, Farinon AM (1992) Wound infection after cholecystectomy. Correlation between bacteria in bile and wound infection after operation on the gallbladder for acute and chronic gallstone disease. Eur J Surg 158:109–112
Gunn A (1981) Acute cholecystitis. Practitioner 225:491–497
Hirota M, Takada T, Kawarada Y et al (2007) Diagnostic criteria and severity assessment of acute cholecystitis: Tokyo Guidelines. J Hepatobiliary Pancreat Surg 14:78–82
Hoem D, Viste A, Horn A et al (2006) Cholecystectomy improves long-term success after endoscopic treatment of CBD stones. Hepatogastroenterology 53:655–659
Hunt DR, Chu FC (2000) Gangrenous cholecystitis in the laparoscopic era. Aust NZ J Surg 70:428–430
Isayama H, Komatsu Y, Tsujino T et al (2004) A prospective randomised study of „covered“ versus „uncovered“ diamond stents for the management of distal malignant biliary obstruction. Gut 53:729–734
Judy AS, Berlin JA, Escarce JJ et al (1994) Revised estimates of diagnostic test sensitivity and specificity in suspected biliary tract disease. Arch Intern Med 154:2573–2581
Kim DU, Kang DH, Kim GH et al (2012) Bilateral biliary drainage for malignant hilar obstruction using the ‚stent-in-stent‘ method with a Y-stent: efficacy and complications. Eur J Gastroenterol Hepatol 26 (Epub ahead of print)
Kim PN, Lee KS, Kim IY et al (1994) Gallbladder perforation: comparison of US findings with CT. Abdom Imaging 19:239–242
Lammert F, Neubrand MW, Bittner R et al (2007) S3-guidelines for diagnosis and treatment of gallstones. German Society for Digestive and Metabolic Diseases and German Society for Surgery of the Alimentary Tract. Z Gastroenterol 45:971–1001
Lubasch A, Lode H (2000) Antibiotic therapy in cholecystitis, cholangitis and pancreatitis. Internist (Berl) 41:168–174
Menakuru SR, Kaman L, Behera A et al (2004) Current management of gall bladder perforations. ANZ J Surg 74:843–846
Miyayama S, Yamashiro M, Takeda T et al (2008) Acute cholecystitis caused by malignant cystic duct obstruction: treatment with metallic stent placement. Cardiovasc Intervent Radiol 31(Suppl 2):221–226
Moyson J, Thill V, Simoens Ch et al (2008) Laparoscopic cholecystectomy for acute cholecystitis in the elderly: a retrospective study of 100 patients. Hepatogastroenterology 55:1975–1980
Pedrosa CS, Casanova R, Rodriguez R (1981) CT findings in subacute perforation of the gallbladder: report on 5 cases. Eur J Radiol 1:137–142
Samie A, Dette S, Vöhringer U et al (2012) Fully covered self-expandable metal stents for treatment of malignant and benign biliary strictures. World J Gastrointest Endosc 4:405–408
Shaffer EA (2006) Gallstone disease: epidemiology of gallbladder stone disease. Best Pract Res Clin Gastroenterol 20:981–996
Sood BP, Kalra N, Gupta S et al (2002) Role of sonography in the diagnosis of gallbladder perforation. J Clin Ultrasound 30:270–274
Statistisches Bundesamt, https://www.destatis.de/SiteGlobals/Forms/Suche/Servicesuche_Formular.html?nn=177590&resourceId=47156&input_=177590&pageLocale=DE&searchUrl=http%3A%2F%2Fwww.destatis.de%2FDE%2FMeta%2FSuche%2FSuche.html&cms_search=cholezystitis&submit=senden&sort=dateOfIssue&cms_facet=&documentType=ALL&dateOfIssue=ALL&switchsource=solr+Internet&x=0&y=0
Stefanidis D, Sirinek KR, Bingener J (2006) Gallbladder perforation: risk factors and outcome. J Surg Res 131:204–208
Swanepoel CR, Floyd A, Allison H et al (1983) Acute acalculous cholecystitis complicating systemic lupus erythematosus: case report and review. Br Med J (Clin Res Ed) 286:251–252
Tanaka M, Takahashi H, Yajima Y et al (1997) Idiopathic perforation of the gallbladder: report of a case and a review of the Japanese literature. Surg Today 27:360–363
Tokunaga Y, Nakayama N, Ishikawa Y et al (1997) Surgical risks of acute cholecystitis in elderly. Hepatogastroenterology 44:671–676
Trowbridge RL, Rutkowski NK, Shojania KG (2003) Does this patient have acute cholecystitis? JAMA 289:80–86
Weiss CA, Schwartz RW (2002) Current diagnosis and treatment of cholecystitis. Curr Surg 59:51–54
Yokoe M, Takada T, Strasberg SM et al (2012) New diagnostic criteria and severity assessment of acute cholecystitis in revised Tokyo Guidelines. J Hepatobiliary Pancreat Sci 19:578–585
Ziessman HA (2003) Acute cholecystitis, biliary obstruction, and biliary leakage. Semin Nucl Med 33:279–296
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Götzky, K., Landwehr, P. & Jähne, J. Epidemiologie und Klinik der akuten Cholezystitis. Chirurg 84, 179–184 (2013). https://doi.org/10.1007/s00104-012-2355-1
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DOI: https://doi.org/10.1007/s00104-012-2355-1