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Epidemiologie psychisch komorbider Störungen bei chronisch körperlichen Erkrankungen

Comorbid psychological disorders in patients with chronic somatic diseases

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Bundesgesundheitsblatt - Gesundheitsforschung - Gesundheitsschutz Aims and scope

Zusammenfassung

Anhand einer Literaturübersicht wird ein Überblick gegeben zur Erfassung psychischer Komorbidität in epidemiologischen Studien, zu den Prävalenzraten psychischer Komorbidität und zum Einfluss psychischer Erkrankungen auf das Entstehen und den Verlauf chronischer Erkrankungen am Beispiel koronarer Herzerkrankungen. Psychische Komorbidität geht mit verminderter Lebensqualität, schlechterem Krankheitsverlauf und erhöhter Mortalität einher, wie zahlreiche Studien an Patienten mit koronaren Herzerkrankungen und anderen chronischen Erkrankungen zeigen. Trotz valider Screeningverfahren, die groß angelegte Bevölkerungsstudien ermöglichen, stellen sich diagnostische Probleme beispielsweise bei der Trennung psychischer und somatischer Symptome und der zuverlässigen Diagnostik somatischer Erkrankungen. Eine nicht erkannte psychische Komorbidität ist in der medizinischen Versorgung häufig. Sie stellt für den weiteren somatischen sowie auch psychischen Krankheitsverlauf ein hohes Risiko dar, das sowohl mit individuellem Leid, aber auch mit erheblichen gesundheitsökonomischen Konsequenzen einhergeht. Forschungsbedarf besteht zu geeigneten Interventionen bei komorbid erkrankten Patienten und zur Verbesserung der Versorgungssituation.

Abstract

Based on the literature, the assessment of psychological comorbidity in epidemiological studies is reviewed along with prevalence rates of psychological comorbidity and the effect of mental diseases on the development and course of chronic disease as exemplified by coronary heart disease. Psychological comorbidity is associated with reduced quality of life, disease progression, and increased mortality, as numerous studies in coronary heart disease and other chronic diseases have shown. In spite of available valid screening measures which enable large population surveys, diagnostic problems remain, especially with respect to separating mental and somatic symptoms and diagnosing somatic diseases reliably. Psychological comorbidity is frequently overlooked in medical care and poses a high risk for the future somatic and mental course of disease, associated with individual suffering and serious health economic consequences. There is a need for research on suitable interventions for patients with chronic disorders and psychological comorbidity in order to improve their care.

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Literatur

  1. Hodeck J, Ruhe A, Greiner W (2009) Gesundheitsbezogene Lebensqualität bei Multimorbidität im Alter. Bundesgesundheitsbl Gesundheitsforsch Gesundheitsschutz 52:1188–1201

    Article  Google Scholar 

  2. Bundesärztekammer (BÄK), Kassenärztliche Bundesvereinigung (KBV), Arbeitsgemeinschaft der Wissenschaftlichen Medizinischen Fachgesellschaften (AWMF) (2010) Nationale VersorgungsLeitlinie Chronische Herzinsuffizienz – Langfassung. Version 1.2. Retrieved from: http://www.versorgungsleitlinien.de/themen/herzinsuffizienz

  3. Scott K, Bruffaerts R, Tsang A et al (2007) Depression-anxiety relationships with chronic physical conditions: results from the World Mental Health Surveys. J Affect Disord 103:113–120

    Article  CAS  PubMed  Google Scholar 

  4. Pieper L, Schulz H, Klotsche J et al (2008) Depression als komorbide Störung in der primärärztlichen Versorgung. Bundesgesundheitsbl Gesundheitsforsch Gesundheitsschutz 51:411–421

    Article  CAS  Google Scholar 

  5. Herrmann CH, Buss U, Snaith RP (1995) HADS-D – Hosptial Anxiety and Depression Scale – Deutsche Version: Ein Fragebogen zur Erfassung von Angst und Depressivität in der somatischen Medizin. Hans Huber, Bern

  6. Löwe B, Spitzer RL, Zipfel S, Herzog W (2002) Gesundheitsfragebogen für Patienten (PHQ-D): Manual und Testunterlagen. Pfizer, Karlsruhe

  7. Hahn D, Reuter K, Härter M (2006) Screening for affective and anxiety disorders in medical patients. GMS PsychoSoc Med 3:1–9

    Google Scholar 

  8. First M, Spitzer R, Gibbon M, Williams J (2002) Structured clinical interview for DSM-IV Axis I Disorders, Research Version, Non-Patient Edition (SCID-I/NP). Biometrics Research, New York State Psychiatric Institute, New York

  9. Kessler R, Ustun T (2004) The World Mental Health (WMH) survey initiative version of the World Health Organization (WHO) Composite International Diagnostic Interview (CIDI). Int J Methods Psychiatr Res 13:93–121

    Article  PubMed  Google Scholar 

  10. Jacobi F, Wittchen HU, Holting C et al (2004) Prevalence, co-morbidity and correlates of mental disorders in the general population: results from the German Health Interview and Examination Survey (GHS). Psychol Med 34:594–611

    Article  Google Scholar 

  11. Kessler RC, Chiu WT, Demler O et al (2005) Prevalence, severity, and comorbidity of 12-month DSM-IV disorders in the National Comorbidity Survey Replication. Arch Gen Psychiatry 62:617–627

    Article  PubMed  Google Scholar 

  12. Jacobi F, Wittchen HU, Holting C et al (2002) Estimating the prevalence of mental and somatic disorders in the community: aims and methods of the German National Health Interview and Examination Survey. Int J Methods Psychiatr Res 11:1–18

    Article  PubMed  Google Scholar 

  13. Ladwig KH, Marten-Mittag B, Lowel H et al (2005) C-reactive protein, depressed mood, and the prediction of coronary heart disease in initially healthy men: results from the MONICA-KORA Augsburg Cohort Study 1984–1998. Eur Heart J 26:2537–2542

    Article  CAS  PubMed  Google Scholar 

  14. Siewert U, Fendrich K, Doblhammer-Reiter G et al (2010) Health care consequences of demographic changes in Mecklenburg-West Pomerania: projected case numbers for age-related diseases up to the year 2020, based on the Study of Health in Pomerania (SHIP). Dtsch Arztebl Int 107:328–334

    PubMed  Google Scholar 

  15. Michal M, Wiltink J, Till Y et al (2010) Type-D personality and depersonalization are associated with suicidal ideation in the German general population aged 35–74: results from the Gutenberg heart study. J Affect Disord 125:227–233

    Article  PubMed  Google Scholar 

  16. Baumeister H, Kriston L, Bengel J, Härter M (2010) High agreement of self-report and physician-diagnosed somatic conditions yields limited bias in examining mental-physical comorbidity. J Clin Epidemiol 63:558–565

    Article  PubMed  Google Scholar 

  17. Kohler M, Ziese T (2004) Telefonischer Gesundheitssurvey des Robert Koch-Instituts zu chronischen Krankheiten und ihren Bedingungen. Deskriptiver Ergebnisbericht. Robert Koch-Institut, Berlin

  18. Wittchen HU, Jacobi F (2005) Size and burden of mental disorders in Europe – a critical review and appraisal of 27 studies. Eur Neuropsychopharmacol 15:357–376

    Article  CAS  PubMed  Google Scholar 

  19. Nutt DJ, Kessler RC, Alonso J et al (2007) Consensus statement on the benefit to the community of ESEMeD (European Study of the Epidemiology of Mental Disorders) survey data on depression and anxiety. J Clin Psychiatry 68(Suppl 2):42–48

    PubMed  Google Scholar 

  20. Kovess-Masfety V, Alonso J, Brugha TS et al (2007) Differences in lifetime use of services for mental health problems in six European countries. Psychiatr Serv 58:213–220

    Article  PubMed  Google Scholar 

  21. Beekman AT, Kriegsman DM, Deeg DJ, Tilburg W van (1995) The association of physical health and depressive symptoms in the older population: age and sex differences. Soc Psychiatry Psychiatr Epidemiol 30:32–38

    Article  CAS  PubMed  Google Scholar 

  22. Kuehner C (2003) Gender differences in unipolar depression: an update of epidemiological findings and possible explanations. Acta Psychiatr Scand 108:163–174

    Article  CAS  PubMed  Google Scholar 

  23. Katon WJ, Lin E, Russo J, Unutzer J (2003) Increased medical costs of a population-based sample of depressed elderly patients. Arch Gen Psychiatry 60:897–903

    Article  PubMed  Google Scholar 

  24. DGPPN, BÄK, KBV, AWMF, AkdÄ, BPtK, BApK, DAGSHG, DEGAM, DGPM, DGPs, DGRW, für die Leitliniengruppe Unipolare Depression (Hrsg) (2009) S3-Leitlinie/Nationale VersorgungsLeitlinie Unipolare Depression. DGPPN, ÄZQ, AWMF, Berlin, Düsseldorf; retrieved from: http://www.versorgungsleitlinien.de

  25. Bijl RV, Graaf R de, Hiripi E et al (2003) The prevalence of treated and untreated mental disorders in five countries. Health Aff (Millwood) 22:122–133

    Google Scholar 

  26. Somers JM, Goldner EM, Waraich P, Hsu L (2006) Prevalence and incidence studies of anxiety disorders: a systematic review of the literature. Can J Psychiatry 51:100–113

    PubMed  Google Scholar 

  27. Magee WJ, Eaton WW, Wittchen HU et al (1996) Agoraphobia, simple phobia, and social phobia in the National Comorbidity Survey. Arch Gen Psychiatry 53:159–168

    CAS  PubMed  Google Scholar 

  28. Jacobi F, Klose M, Wittchen HU (2004) Psychische Störungen in der deutschen Allgemeinbevölkerung: Inanspruchnahme von Gesundheitsleistungen und Ausfalltage. Bundesgesundheitsbl Gesundheitsforsch Gesundheitsschutz 47:736–744

    CAS  Google Scholar 

  29. Bryant C, Jackson H, Ames D (2008) The prevalence of anxiety in older adults: methodological issues and a review of the literature. J Affect Disord 109:233–250

    Article  PubMed  Google Scholar 

  30. Katon W, Lin EH, Kroenke K (2007) The association of depression and anxiety with medical symptom burden in patients with chronic medical illness. Gen Hosp Psychiatry 29:147–155

    Article  PubMed  Google Scholar 

  31. Härter M, Baumeister H, Bengel J (Hrsg) (2007) Psychische Störungen bei körperlichen Erkrankungen. Springer, Berlin Heidelberg New York Tokyo

  32. Moussavi S, Chatterji S, Verdes E et al (2007) Depression, chronic diseases, and decrements in health: results from the World Health Surveys. Lancet 370:851–858

    Article  PubMed  Google Scholar 

  33. Singer S, Das-Munshi J, Brahler E (2010) Prevalence of mental health conditions in cancer patients in acute care – a meta-analysis. Ann Oncol 21:925–930

    Article  CAS  PubMed  Google Scholar 

  34. Beutel M (2005) Psychotherapie bei somatischen Erkrankungen aus psychodynamischer Sicht. In: Faller H (Hrsg) Psychotherapie bei somatischen Erkrankungen. Thieme, Stuttgart, S 122–140

  35. Frasure-Smith N, Lesperance F (2010) Depression and cardiac risk: present status and future directions. Heart 96:173–176

    Article  PubMed  Google Scholar 

  36. Nicholson A, Kuper H, Hemingway H (2006) Depression as an aetiologic and prognostic factor in coronary heart disease: a meta-analysis of 6362 events among 146.538 participants in 54 observational studies. Eur Heart J 27:2763–2774

    Article  PubMed  Google Scholar 

  37. Whooley MA, Jonge P de, Vittinghoff E et al (2008) Depressive symptoms, health behaviors, and risk of cardiovascular events in patients with coronary heart disease. JAMA 300:2379–2388

    Article  CAS  PubMed  Google Scholar 

  38. Melle JP van, Jonge P de, Spijkerman TA et al (2004) Prognostic association of depression following myocardial infarction with mortality and cardiovascular events: a meta-analysis. Psychosom Med 66:814–822

    Article  PubMed  Google Scholar 

  39. Rozanski A, Blumenthal JA, Davidson KW et al (2005) The epidemiology, pathophysiology, and management of psychosocial risk factors in cardiac practice: the emerging field of behavioral cardiology. J Am Coll Cardiol 45:637–651

    Article  PubMed  Google Scholar 

  40. Lichtman JH, Bigger JT Jr, Blumenthal JA et al (2008) Depression and coronary heart disease: recommendations for screening, referral, and treatment: a science advisory from the American Heart Association Prevention Committee of the Council on Cardiovascular Nursing, Council on Clinical Cardiology, Council on Epidemiology and Prevention, and Interdisciplinary Council on Quality of Care and Outcomes Research: endorsed by the American Psychiatric Association. Circulation 118:1768–1775

    Article  PubMed  Google Scholar 

  41. Ladwig KH, Lederbogen F, Völler H et al (2008) Positionspapier zur Bedeutung von psychosozialen Faktoren in der Kardiologie. Kardiologe 2:274–287

    Article  Google Scholar 

  42. Frasure-Smith N, Lespérance F, Gravel G et al (2000) Depression and health-care costs during the first year following myocardial infarction. J Psychosom Res 48:471–478

    Article  CAS  PubMed  Google Scholar 

  43. Linden W, Phillips MJ, Leclerc J (2007) Psychological treatment of cardiac patients: a meta-analysis. Eur Heart J 28:2972–2984

    Article  PubMed  Google Scholar 

  44. Roest AM, Martens EJ, Jonge P de, Denollet J (2010) Anxiety and risk of incident coronary heart disease: a meta-analysis. J Am Coll Cardiol 56:38–46

    Article  PubMed  Google Scholar 

  45. Smoller JW, Pollack MH, Wassertheil-Smoller S et al (2007) Panic attacks and risk of incident cardiovascular events among postmenopausal women in the Women’s Health Initiative Observational Study. Arch Gen Psychiatry 64:1153–1160

    Article  PubMed  Google Scholar 

  46. Ladwig KH, Baumert J, Marten-Mittag B et al (2008) Posttraumatic stress symptoms and predicted mortality in patients with implantable cardioverter-defibrillators: results from the prospective living with an implanted cardioverter-defibrillator study. Arch Gen Psychiatry 65:1324–1330

    Article  PubMed  Google Scholar 

  47. Frasure-Smith N, Lesperance F (2008) Depression and anxiety as predictors of 2-year cardiac events in patients with stable coronary artery disease. Arch Gen Psychiatry 65:62–71

    Article  CAS  PubMed  Google Scholar 

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Beutel, M., Schulz, H. Epidemiologie psychisch komorbider Störungen bei chronisch körperlichen Erkrankungen. Bundesgesundheitsbl. 54, 15–21 (2011). https://doi.org/10.1007/s00103-010-1191-z

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