Zusammenfassung
Eine Dekade nach Beginn der Diskussion, ob die Beatmung durch Laienreanimation in den ersten Minuten verzichtbar sei, wird der Informationsstand zum Thema aktualisiert und kommentiert. Tierexperimente und eine prospektive randomisierte Patientenstudie hatten zunächst nahe gelegt, dass eine Beatmung unter diesen Umständen ohne Folgen für das individuelle Outcome unterbleiben könne. Die Analyse der neueren Literatur jedoch zeigt, dass Thoraxkompressionen ohne Beatmung der standardmäßigen kardiopulmonalen Reanimation („cardiopulmonary resuscitation“, CPR) in keinem Fall überlegen sind, und nur in sehr speziellen Szenarien gleichwertig sein könnten. Anstatt bewährte Bausteine der „Basic-life-support-“ (BLS-) Ausbildung und -Praxis in Frage zu stellen, sollte eine weitere Verbesserung der Ausbildung von Laien und professionellen Rettern angestrebt werden, sowie die durch Leitstellenpersonal geführte Telefon-CPR evaluiert und, bei Nachweis einer Verbesserung des Outcomes, diese auch forciert eingesetzt werden. Zukünftige Studien sollten sich weniger auf die Abschaffung als auf die Optimierung der Beatmung unter den spezifischen Bedingungen der CPR konzentrieren.
Abstract
A decade after the onset of a discussion whether ventilation could be omitted from bystander basic life support (BLS) algorithms, the state of the evidence is reevaluated. Initial animal studies and a prospective randomized patient trial had suggested that omission of ventilation during the first minutes of lay cardiopulmonary resuscitation (CPR) did not impair patient outcomes. More recent studies demonstrate, however, that this may hold true only in very specific scenarios, and that the chest compression-only technique was never superior to standard BLS. Instead of calling basics of BLS training and practice into question, more and better training of lay persons and professionals appears mandatory, and targeted use of dispatcher-guided telephone CPR should be evaluated and, if it improves outcome, it should be encouraged. Future studies should focus much less on the omission but on the optimization of ventilation under the specific conditions of CPR.
Literatur
American Heart Association in collaboration with the International Liaison Committee on Resuscitation (2000) Guidelines 2000 for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care. Circulation 102 [Suppl 8]:I1–384
Acute Respiratory Distress Syndrome Network (2000) Ventilation with lower tidal volumes as compared with traditional tidal volumes for acute lung injury and the acute respiratory distress syndrome. N Engl J Med 342:1301–1308
Assar D, Chamberlain D, Colquhoun M et al. (1998) A rationale for staged teaching of basic life support. Resuscitation 39:137–143
Assar D, Chamberlain D, Colquhoun M, Donnelly P, Handley AJ, Leaves S, Kern KB (2000) Randomised controlled trials of staged teaching for basic life support. 1. Skill acquisition at bronze stage. Resuscitation 45:7–15
Aufderheide TP, Sigurdsson G, Pirrallo RG et al. (2004) Hyperventilation-induced hypotension during cardiopulmonary resuscitation. Circulation 109:1960–1965
Ayoub IM, Brown DJ, Gazmuri RJ (2001) Transtracheal oxygenation: an alternative to endotracheal intubation during cardiac arrest. Chest 120:1663–1670
Babbs CF, Kern KB (2002) Optimum compression to ventilation ratios in CPR under realistic, practical conditions: a physiological and mathematical analysis. Resuscitation 54:147–157
Berg RA (2000) Role of mouth-to-mouth rescue breathing in bystander cardiopulmonary resuscitation for asphyxial cardiac arrest. Crit Care Med 28 [Suppl 11]:N193–195
Berg RA, Kern KB, Sanders AB, Otto CW, Hilwig RW, Ewy GA (1993) Bystander cardiopulmonary resuscitation. Is ventilation necessary? Circulation 88:1907–1915
Berg RA, Kern KB, Hilwig RW, Ewy GA (1997) Assisted ventilation during „bystander“ CPR in a swine acute myocardial infarction model does not improve outcome. Circulation 96:4364–4371
Berg RA, Kern KB, Hilwig RW, Berg MD, Sanders AB, Otto CW, Ewy GA (1997) Assisted ventilation does not improve outcome in a porcine model of single-rescuer bystander cardiopulmonary resuscitation. Circulation 95:1635–1641
Berg RA, Hilwig RW, Kern KB, Babar I, Ewy GA (1999) Simulated mouth-to-mouth ventilation and chest compressions (bystander cardiopulmonary resuscitation) improves outcome in a swine model of prehospital pediatric asphyxial cardiac arrest. Crit Care Med 27:1893–1899
Berg RA, Hilwig RW, Kern KB, Ewy GA (2000) „Bystander“ chest compressions and assisted ventilation independently improve outcome from piglet asphyxial pulseless „cardiac arrest“. Circulation 101:1743–1748
Berg RA, Sanders AB, Kern KB, Hilwig RW, Heidenreich JW, Porter ME, Ewy GA (2001) Adverse hemodynamic effects of interrupting chest compressions for rescue breathing during cardiopulmonary resuscitation for ventricular fibrillation cardiac arrest. Circulation 104:2465–2470
Bossaert L, Hoeyweghen R van (1989) Evaluation of cardiopulmonary resuscitation (CPR) techniques. The Cerebral Resuscitation Study Group. Resuscitation 17 Suppl:S99–109; discussion S199–206
Brenner BE, Van DC, Lazar EJ, Camargo C (2000) Determinants of physician reluctance to perform mouth-to-mouth resuscitation. J Clin Epidemiol 53:1054–1061
Casper K, Murphy G, Weinstein C, Brinsfield K (2003) A comparison of cardiopulmonary resuscitation rates of strangers versus known bystanders. Prehosp Emerg Care 7:299–302
Chandra NC, Gruben KG, Tsitlik JE et al. (1994) Observations of ventilation during resuscitation in a canine model. Circulation 90:3070–3075
Criley JM, Niemann JT, Rosborough JP, Hausknecht M (1986) Modifications of cardiopulmonary resuscitation based on the cough. Circulation 74:IV42–50
Dick WF, Brambrink AM, Kern T (1999) Kardiopulmonale Reanimation „oben ohne“? Soll die Herz-Lungen-Wiederbelebung künftig ohne Beatmung erfolgen? Anaesthesist 48:290–300
Dorph E, Wik L, Steen PA (2002) Effectiveness of ventilation-compression ratios 1:5 and 2:15 in simulated single rescuer paediatric resuscitation. Resuscitation 54:259–264
Dorph E, Wik L, Stromme TA, Eriksen M, Steen PA (2003) Quality of CPR with three different ventilation: compression ratios. Resuscitation 58:193–201
Dorph E, Wik L, Stromme TA, Eriksen M, Steen PA (2004) Oxygen delivery and return of spontaneous circulation with ventilation: compression ratio 2:30 versus chest compressions only CPR in pigs. Resuscitation 60:309–318
Greingor JL (2002) Quality of cardiac massage with ratio compression-ventilation 5/1 and 15/2. Resuscitation 55:263–267
Hallstrom A, Cobb L, Johnson E, Copass M (2000) Cardiopulmonary resuscitation by chest compression alone or with mouth-to-mouth ventilation. N Engl J Med 342:1546–1553
Harada Y, Fuseno H, Ohtomo T, Yamahara Y, Nakamura M (1991) Self-administered hyperventilation cardiopulmonary resuscitation for 100 s of cardiac arrest during Holter monitoring. Chest 99:1310–1312
Hevesi ZG, Thrush DN, Downs JB, Smith RA (1999) Cardiopulmonary resuscitation: effect of CPAP on gas exchange during chest compressions. Anesthesiology 90:1078–1083
Hoeyweghen RJ van, Bossaert LL, Mullie A, Calle P, Martens P, Buylaert WA, Delooz H (1993) Quality and efficiency of bystander CPR. Belgian Cerebral Resuscitation Study Group. Resuscitation 26:47–52
Jawan B, Cheung HK, Chong ZK et al. (2000) Aspiration in transtracheal oxygen insufflation with different insufflation flow rates during cardiopulmonary resuscitation in dogs. Anesth Analg 91:1431–1435
Kawamae K, Murakawa M, Otsuki M, Matsumoto Y, Tase C (2001) Precordial compression without airway management induces lung injury in the rodent cardiac arrest model with central apnea. Resuscitation 51:165–171
Kern KB (2000) Cardiopulmonary resuscitation without ventilation. Crit Care Med 28 [Suppl 11]:N186–189
Kern KB, Hilwig RW, Berg RA, Ewy GA (1998) Efficacy of chest compression-only BLS CPR in the presence of an occluded airway. Resuscitation 39:179–188
Kinney SB, Tibballs J (2000) An analysis of the efficacy of bag-valve-mask ventilation and chest compression during different compression-ventilation ratios in manikin-simulated paediatric resuscitation. Resuscitation 43:115–120
Kleinsasser A, Lindner KH, Schaefer A, Loeckinger A (2002) Decompression-triggered positive-pressure ventilation during cardiopulmonary resuscitation improves pulmonary gas exchange and oxygen uptake. Circulation 106:373–378
Langhelle A, Sunde K, Wik L, Steen PA (2000) Arterial blood-gases with 500- versus 1000-ml tidal volumes during out-of-hospital CPR. Resuscitation 45:27–33
Liberman M, Lavoie A, Mulder D, Sampalis J (1999) Cardiopulmonary resuscitation: errors made by pre-hospital emergency medical personnel. Resuscitation 42:47–55
Markstaller K, Karmrodt J, Doebrich M et al. (2002) Dynamic computed tomography: a novel technique to study lung aeration and atelectasis formation during experimental CPR. Resuscitation 53:307–313
Markstaller K, Herweling A, Karmrodt J et al. (2003) Vergleich unterschiedlicher Beatmungsstrategien während experimenteller kardiopulmonaler Reanimation mittels ultraschneller paO2 Messung und dynamischer Computertomographie. Anaesthesiol Intensivmed 44:764
Markstaller K, Kauczor HU, Weiler N et al. (2003) Lung density distribution in dynamic CT correlates with oxygenation in ventilated pigs with lavage ARDS. Br J Anaesth 91:1–10
Noc M, Weil MH, Tang W, Turner T, Fukui M (1995) Mechanical ventilation may not be essential for initial cardiopulmonary resuscitation. Chest 108:821–827
Safar P, Bircher N, Pretto E Jr et al. (1998) Reappraisal of mouth-to-mouth ventilation during bystander-initiated CPR. Circulation 98:608–610
Sanders AB, Kern KB, Berg RA, Hilwig RW, Heidenrich J, Ewy GA (2002) Survival and neurologic outcome after cardiopulmonary resuscitation with four different chest compression-ventilation ratios. Ann Emerg Med 40:553–562
Shaw DP, Rutherford JS, Williams MJ (1997) The mechanism of blood flow in cardiopulmonary resuscitation—introducing the lung pump. Resuscitation 35:255–258
Stallinger A, Wenzel V, Oroszy S, Mayr VD, Idris AH, Lindner KH, Hormann C (2001) The effects of different mouth-to-mouth ventilation tidal volumes on gas exchange during simulated rescue breathing. Anesth Analg 93:1265–1269
Turner I, Turner S, Armstrong V (2002) Does the compression to ventilation ratio affect the quality of CPR: a simulation study. Resuscitation 52:55–62
Wenzel V, Keller C, Idris AH, Dorges V, Lindner KH, Brimacombe JR (1999) Effects of smaller tidal volumes during basic life support ventilation in patients with respiratory arrest: good ventilation, less risk? Resuscitation 43:25–29
Wenzel V, Voelckel WG, Krismer AC et al. (2001) Die neuen internationalen Richtlinien zur kardiopulmonalen Reanimation. Eine Analyse und Kommentierung der wichtigsten Änderungen. Anaesthesist 50:342–357
Winkler M, Mauritz W, Hackl W, Gilly H, Weindlmayr-Goettel M, Steinbereithner K, Schindler I (1998) Effects of half the tidal volume during cardiopulmonary resuscitation on acid-base balance and haemodynamics in pigs. Eur J Emerg Med 5:201–206
Interessenkonflikt:
Der korrespondierende Autor versichert, dass keine Verbindungen mit einer Firma, deren Produkt in dem Artikel genannt ist, oder einer Firma, die ein Konkurrenzprodukt vertreibt, bestehen.
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Markstaller, K., Eberle, B. & Dick, W.F. Kardiopulmonale Reanimation „oben ohne“. Anaesthesist 53, 927–936 (2004). https://doi.org/10.1007/s00101-004-0749-2
Issue Date:
DOI: https://doi.org/10.1007/s00101-004-0749-2