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Response to humor in depression: A predictor and evaluator of patient change?

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Summary

Response to humor in the form of riddles and jokes was studied in 18 women patients with severe neurotic and psychotic depressions. The patients were observed during and following a four-day series of intravenous drip infusions of 5 per cent glucose in saline; some patients received 500 mg. of nialamide in this infusion in random double-blind distribution. Patients were tested for humor response on each of the four treatment days and at the end of a two-week follow-up period. A psychologist independently administered the MMPI and the Reck Depression Inventory before, immediately following, and two weeks after the termination of, the intravenous phase; her evaluations were used as criteria for validating the humor response. Results offered tentative support for the significance of the humor response as a predictor and evaluator of change in depressed patients. Clinical implications and suggestions for refinement of this new method were discussed.

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From the department of medical research, Spring Grove State Hospital, Baltimore 28, Md.

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Nussbaum, K., Michaux, W.W. Response to humor in depression: A predictor and evaluator of patient change?. Psych Quar 37, 527–539 (1963). https://doi.org/10.1007/BF01617751

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