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Analgetika, nicht-steroidale Antirheumatika, Glucocorticoide

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Morbus Bechterew

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Literatur

  • Abramson S, Edelson H, Kaplan H, Ludewig R, Weissmann G (1984) Inhibition of neutrophil activation by nonsteroidal anti-inflammatory drugs. Am J Med 77: 3–6.

    Google Scholar 

  • Adams SS, Cobb R (1958) A possible basis for the anti-inflammatory activity of salizylates and other nonhormonal anti-rheumatic drugs. Nature 181: 773

    Google Scholar 

  • Amin AR, Vyas P, Attur M, Leszczynska-Piziak J, Patel IR, Weissmann G, Abramson SB (1995) The mode of action of aspirin-like drugs: effect on inducible nitric oxide synthase. Proc Natl Acad Sci U S A 92: 7926–7930.

    PubMed  Google Scholar 

  • Baele G, Rasquin K, Barbier F (1983) Effects of oxametacin on coumarin anticoagulation and on platelet function in humans. Arzneimittel-forschung 33: 149–152

    PubMed  Google Scholar 

  • Balfour JA, Fitton A, Barradell LB (1996) Lornoxicam. A review of its pharmacology and therapeutic potential in the management of painful and inflammatory conditions. Drugs 51: 639–657.

    PubMed  Google Scholar 

  • Bianchi M, Rossoni G, Sacerdote P, Panerai AE (1999) Effects of tramadol on experimental inflammation. Fundam Clin Pharmacol 13: 220–225

    PubMed  Google Scholar 

  • Bianchi Porro G, Caruso I, Petrillo M, Montrone F, Ardizzone S (1991) A double-blind gastroscopic evaluation of the effects of etodolac and naproxen on the gastrointestinal mucosa of rheumatic patients. J Intern Med 229: 5–8.

    PubMed  Google Scholar 

  • Botting R (2000) Paracetamol-inhibitable COX-2. J Physiol Pharmacol 51: 609–618

    PubMed  Google Scholar 

  • Braun J, Bollow M, Seyrekbasan F, Haberle HJ, Eggens U, Mertz A (1996) Computed tomography guided corticosteroid injection of the sacroiliac joint in patients with spondylarthropathy with sacroiliitis: clinical outcome and follow-up by dynamic magnetic resonance imaging. J Rheumatol 23: 659–664

    PubMed  Google Scholar 

  • Braun J, Sieper J (2002) New and old therapeutic options in ankylosing spondylitis-is there an indication for sulfasalazine? Z Rheumatol 61: 151–158

    PubMed  Google Scholar 

  • Brooks P (1998) Use and benefits of nonsteroidal anti-inflammatory drugs. Am J Med 104: 9S–13S; discussion 21S–22S.

    Article  Google Scholar 

  • Brune K (1985) Pharmacokinetic factors as causes of variability in response to nonsteroidal anti-inflammatory drugs. Agents Actions Suppl 17: 59–63

    PubMed  Google Scholar 

  • Brune K, Neubert A (2001) Pharmacokinetic and pharmacodynamic aspects of the ideal COX-2 inhibitor: a pharmacologist’s perspective. Clin Exp Rheumatol 19: S51–57.

    Google Scholar 

  • Buttgereit F (2000) Mechanisms and clinical relevance of nongenomic glucocorticoid actions. Z Rheumatol 59: II/119–123.

    Article  Google Scholar 

  • Buttgereit F (2001) [Wirkungsmechanismen und Wirkungen der Glucocorticoide]. Z Rheumatol 60: 117–119.

    PubMed  Google Scholar 

  • Buttgereit F, da Silva JAP, Boers M, Burmester GR, Cutolo M, Jacobs J, Kirwan J, Köhler L, van Riel P, Vischer T, Bijlsma JWJ (2002a) Standardised nomenclature for glucocorticoid dosages and glucocorticoid treatment regimens: current questions and tentative answers in rheumatology. Ann Rheum Dis 61: 718–722

    Article  PubMed  Google Scholar 

  • Buttgereit F, Scheffold A (2002b) Rapid glucocorticoid effects on immune cells. Steroids 67: 529–534.

    Article  PubMed  Google Scholar 

  • Calin A, Elswood J (1990) A prospective nationwide cross-sectional study of NSAID usage in 1331 patients with ankylosing spondylitis. J Rheumatol 17: 801–803.

    PubMed  Google Scholar 

  • Carneiro W, de Moraes JP (1968) [Treatment of spinal arthritis with a paracetamol-phenylbutazone combination. Work presented in the VIIth Brazilian Congress of Rheumatology. Guanabara 1968]. Rev Bras Med 25: 481–482.

    PubMed  Google Scholar 

  • Caruso I, Bianchi Porro G (1980) Gastroscopic evaluation of anti-inflammatory agents. Br Med J 280: 75–78.

    PubMed  Google Scholar 

  • Conn HO, Poynard T (1994) Corticosteroids and peptic ulcer: meta-analysis of adverse events during steroid therapy. J Intern Med 236: 619–632

    PubMed  Google Scholar 

  • Danion JM, Schmidt M, Welsch M, Imbs JL, Singer L (1987) [Interaction between non-steroidal anti-inflammatory agents and lithium salts]. Encephale 13: 255–260.

    PubMed  Google Scholar 

  • Davies NM, Anderson KE (1997) Clinical pharmacokinetics of diclofenac. Therapeutic insights and pitfalls. Clin Pharmacokinet 33: 184–213.

    PubMed  Google Scholar 

  • Dougados B, Dijkmans B, Khan M, Maksymowych W, van der Linden S, Brandt J (2002) Conventional treatments for ankylosing spondylitis. Ann Rheum Dis 61Suppl III: iii40–iii50

    PubMed  Google Scholar 

  • Dougados M, Behier JM, Jolchine I, Calin A, van der Heijde D, Olivieri I, Zeidler H, Herman H (2001) Efficacy of celecoxib, a cyclooxygenase 2-specific inhibitor, in the treatment of ankylosing spondylitis: a six-week controlled study with comparison against placebo and against a conventional nonsteroidal antiinflammatory drug. Arthritis Rheum 44: 180–185.

    Article  PubMed  Google Scholar 

  • Dubois RN, Abramson SB, Crofford Lea (1998) Cyclooxygenase in biology and disease. FA-SEB J 12: 1063

    Google Scholar 

  • Emery P, Zeidler H, Kvien TK, Guslandi M, Naudin R, Stead H, Verburg KM, Isakson PC, Hubbard RC, Geis GS (1999) Celecoxib versus diclofenac in long-term management of rheumatoid arthritis: randomised double-blind comparison. Lancet 354: 2106–2111.

    PubMed  Google Scholar 

  • Erkut ZA, Pool C, Swaab DF (1998) Glucocorticoids suppress corticotropin-releasing hormone and vasopressin expression in human hypothalamic neurons. J Clin Endocrinol Metab 83: 2066–2073.

    Article  PubMed  Google Scholar 

  • Fries JF, Miller SR, Spitz PW, Williams CA, Hubert HB, Bloch DA (1990) Identification of patients at risk for gastropathy associated with NSAID use. J Rheumatol Suppl 20: 12–19.

    PubMed  Google Scholar 

  • Furst DE, Hillson JL (1998) What is the role of selective COX-2 inhibitors in the spectrum of NSAID therapy? Rheumatology Grand Rounds 1: 1

    Google Scholar 

  • Gaffney K, Ledingham J, Perry JD (1995) Intra-articular triamcinolone hexacetonide in knee osteoarthritis: factors influencing the clinical response. Ann Rheum Dis 54: 379–381

    PubMed  Google Scholar 

  • Gartner JS, Blough D, Drinkard CR (2000) Tramadol and seizures: a surveilance study in managed care population. Pharmacotherapy 20: 1423–1431

    Article  PubMed  Google Scholar 

  • Gevers G, Dequeker J, van Holsbeeck M, van Vliet-Daskalopoulou E (1994) A high dose (up to 200 mg) tolerance and efficacy study of intra-articular rimexolone (Org 6216) in rheumatoid synovitis of the knee. Clin Rheumatol 13: 103–109

    PubMed  Google Scholar 

  • Gibson TP (1996) Pharmacokinetics, efficacy, and safety of analgesia with a focus on tramadol HCl. Am J Med 101: 47S–53S.

    Google Scholar 

  • Gunaydin I, Pereira PL, Daikeler T, Mohren M, Trubenbach J, Schick Fea (2000) Magnetic resonance imaging guided corticosteroid injection of the sacroiliac joints in patients with therapy resistant spondyloarthropathy: a pilot study. J Rheumatol 27: 424–428

    PubMed  Google Scholar 

  • Hawkey CJ (1999) COX-2 inhibitors. Lancet 353: 307–314.

    Article  PubMed  Google Scholar 

  • Hill HF, Hill AG (1975) Ankylosing spondylitis: open long-term and double-blind crossover studies with naproxen. J Clin Pharmacol 15: 355–362.

    PubMed  Google Scholar 

  • Jones DW, Mansell MA, Samuell CT, Isenberg DA (1987) Renal abnormalities in ankylosing spondylitis. Br J Rheumatol 26: 341–345.

    PubMed  Google Scholar 

  • Joyce DA, Kloda A, Steer JH (1997) Dexamethasone suppresses release of soluble TNF receptors by human monocytes concurrently with TNF-alpha suppression. Immunol Cell Biol 75: 345–350.

    PubMed  Google Scholar 

  • Kaiser H (1998) [Use of glucocorticoids in therapy of rheumatic disease. 1: Value-precautions-choice of drug preparation]. Fortschr Med 116: 44–45.

    Google Scholar 

  • Kaiser H, K. KH (2002). Cortisontherapie. Stuttgart New York, Georg Thieme Verlag.

    Google Scholar 

  • Khan MA (1987) A double blind comparison of diclofenac and indomethacin in the treatment of ankylosing spondylitis. J Rheumatol 14: 118–123.

    PubMed  Google Scholar 

  • Kimberly RP (1991) Mechanisms of action, dosage schedules, and side effects of steroid therapy. Curr Opin Rheumatol 3: 373–379.

    PubMed  Google Scholar 

  • Krzywanek HJ, Breddin K (1977) [Does Diclofenac modify oral anticoagulant therapy and platelet aggregation?]. Med Welt 28: 1843–1845.

    PubMed  Google Scholar 

  • Lehtinen R (1979) Clinical and radiological features of ankylosing spondylitis in the 1950s and 1976 in the same hospital. Scand J Rheumatol 8: 57–61

    PubMed  Google Scholar 

  • Ljunggren B, Lundberg K (1985) In vivo phototoxicity of non-steroidal anti-inflammatory drugs evaluated by the mouse tail technique. Photodermatol 2: 377–382.

    PubMed  Google Scholar 

  • Lourie SH, Denman SJ, Schroeder ET (1977) Association of renal papillary necrosis and ankylosing spondylitis. Arthritis Rheum 20: 917–921.

    PubMed  Google Scholar 

  • Masferrer JL, Reddy ST, Zweifel BS, Seibert K, Needleman P, Gilbert RS, Herschman HR (1994) In vivo glucocorticoids regulate cyclooxygenase-2 but not cyclooxygenase-1 in peritoneal macrophages. J Pharmacol Exp Ther 270: 1340–1344.

    PubMed  Google Scholar 

  • Maugars Y, Mathis C, Berthelot JM, Charlier C, Prost A (1996) Assessment of the efficacy of sacroiliac corticosteroid injections in spondylarthropathies: a double-blind study. Br J Rheumatol 35: 767–770

    PubMed  Google Scholar 

  • McGonagle D, Emery P (2000) Enthesitis, osteitis, microbes, biomechanics, and immune reactivity in ankylosing spondylitis. J Rheumatol 27: 2302–2304

    PubMed  Google Scholar 

  • Nuotto E, Saarialho-Kere U (1988) Actions and interactions of indomethacin and diazepam on performance in healthy volunteers. Pharmacol Toxicol 62: 293–297.

    PubMed  Google Scholar 

  • Ofman JJ, MacLean CH, Straus WL, Morton SC, Berger ML, Roth EA, Shekelle P (2002) A metaanalysis of severe upper gastrointestinal complications of nonsteroidal antiinflammatory drugs. J Rheumatol 29: 804–812.

    PubMed  Google Scholar 

  • Pal B (1987) Use of simple analgesics in the treatment of ankylosing spondylitis. Br J Rheumatol 26: 207–209.

    PubMed  Google Scholar 

  • Peters ND, Ejstrup L (1992) Intravenous methyl-prednisolone pulse therapy in ankylosing spondylitis. Scand J Rheumatol 21: 134–138

    PubMed  Google Scholar 

  • Petrone D, Kamin M, Olson W (1999) Slowing the titration rate of tramadol HCl reduces the incidence of discontinuation due to nausea and/or vomiting: a double-blind randomized trial. J clin Pharm Therapeut 24: 115–123

    Article  Google Scholar 

  • Price R, Sinclair H, Heinrich I, Gibson T (1991) Local injection treatment of tennis elbow-hydrocortisone, triamcinolone and lignocaine compared. Br J Rheumatol 30: 39–44

    PubMed  Google Scholar 

  • Purcell P, Henry D, Melville G (1991) Diclofenac hepatitis. Gut 32: 1381–1385.

    PubMed  Google Scholar 

  • Radschuweit A, Ruttinger HH, Nuhn P, Wohlrab W, Huschka C (2001) UV-induces formation of hydrogen peroxide based on the photochemistry of ketoprofen. Photochem Photobiol 73: 119–127.

    Article  PubMed  Google Scholar 

  • Raffa RB, Friderichs E, Reimann W, Shank RP, Codd EE, Vaught JL (1992) Opioid and nonopioid components independently contribute to the mechanism of action of tramadol, an ‘atypical’ opioid analgesic. J Pharmacol Exp Ther 260: 275–285.

    PubMed  Google Scholar 

  • Rainer F, Pongratz R (2001). Interaktionen nichtsteroidaler Antirheumatika mit anderen Pharmaka. Praktische Rheumatologie. N Thumb, H Bröll, R Czurda, W Siegmeth, JS Smolen. Wien, New York, Springer Verlag. 1: 502–505.

    Google Scholar 

  • Ralston SH, Urquhart J, Brzeski Mea (1990) Prevalence of vertebral compression fractures due to osteoporosis in ankylosing spondylitis. Br Med J 300: 563–565

    Google Scholar 

  • Reig E (2002) Tramadol in Musculoskeletal Pain — A Survey. Clin Rheumatol: S9–S12

    Google Scholar 

  • Richter MB, Woo P, Panayi GS, Trull A, Unger A, Shepherd P (1983) The effects of intravenous pulse methylprednisolone on immunological and inflammatory processes in ankylosing spondylitis. Clin Exp Immunol 53: 51–59.

    PubMed  Google Scholar 

  • Ring J, Przybilla B, Ruzicka T (1987) Nonsteroidal antiinflammatory drugs induce UV-dependent histamine and leukotriene release from peripheral human leukocytes. Int Arch Allergy Appl Immunol 82: 344–346

    PubMed  Google Scholar 

  • Robert L, Wortmann MD (2002) Lipid-lowering agents and myopathy. Curr Opin Rheumatol 14: 643–647

    Article  PubMed  Google Scholar 

  • Rostom A, Wells G, Tugwell P, Welch V, Dube C, McGowan J (2000) The prevention of chronic NSAID induced upper gastrointestinal toxicity: a Cochrane collaboration metaanalysis of randomized controlled trials. J Rheumatol 27: 2203–2214.

    PubMed  Google Scholar 

  • Ruof J, Sangha O, Stucki G (1999) Comparative responsiveness of 3 functional indices in ankylosing spondylitis. J Rheumatol 26: 1959–1963

    PubMed  Google Scholar 

  • Schnitzer TJ, Kamin M, Olson WH (1999) Tramadol allows reduction of naproxen dose among patients with naproxen-responsive osteoarthritis pain: a randomized, double-blind, placebo-controlled study. Arthritis Rheum 42: 1370–1377

    Article  PubMed  Google Scholar 

  • Siegle I, Klein T, Backman JT, Saal JG, Nusing RM, Fritz P (1998) Expression of cyclooxygenase 1 and cyclooxygenase 2 in human synovial tissue: differential elevation of cyclooxygenase 2 in inflammatory joint diseases. Arthritis Rheum 41: 122–129.

    Article  PubMed  Google Scholar 

  • Sieper J, Braun J (2001) New treatment options in ankylosing spondylitis: a role for anti-TNF-alpha therapy. Ann Rheum Dis 60Suppl 3: iii58–61.

    PubMed  Google Scholar 

  • Sieper J, Braun J, Rudwaleit M, Boonen A, Zink A (2002) Ankylosing spondylitis: an overview. Ann Rheum Dis 61Suppl 3: III8–III18.

    PubMed  Google Scholar 

  • Silvola J, Kangasaho M, Tokola O, Vapaatalo H (1982) Effects of nonsteroidal anti-inflammatory drugs on rat gastric mucosal phosphodiesterase activity. Agents Actions 12: 516–520.

    PubMed  Google Scholar 

  • Simon LS, Weaver AL, Graham DY, Kivitz AJ, Lipsky PE, Hubbard RC, Isakson PC, Verburg KM, Yu SS, Zhao WW, Geis GS (1999) Anti-inflammatory and upper gastrointestinal effects of celecoxib in rheumatoid arthritis: a randomized controlled trial. JAMA 282: 1921–1928.

    Article  PubMed  Google Scholar 

  • Singh G, Ramey DR, Morfeld D, Shi H, Hatoum HT, Fries JF (1996) Gastrointestinal tract complications of nonsteroidal anti-inflammatory drug treatment in rheumatoid arthritis. A prospective observational cohort study. Arch Intern Med 156: 1530–1536.

    Article  PubMed  Google Scholar 

  • Stein J (1999) NSAR-Enteropathie. In: Caspary W, Stein J (Hrsg) Darmkrankheiten. Springer, Berlin, pp 519–524

    Google Scholar 

  • Stuck AE, Minder CE, Frey FJ (1989) Risk of infectious complications in patients taking glucocorticosteroids. Rev Infect Dis 11: 954–963.

    PubMed  Google Scholar 

  • Todd PA, Clissold SP (1990) Naproxen. A reappraisal of its pharmacology, and therapeutic use in rheumatic diseases and pain states. Drugs 40:91–137.

    PubMed  Google Scholar 

  • Toussirot E, Wendling D (1998) Current guidelines for the drug treatment of ankylosing spondylitis. Drugs 56: 225–240.

    PubMed  Google Scholar 

  • van Staa TP, Leufkens HG, Abenhaim L, Zhang B, Cooper C (2000) Oral corticosteroids and fracture risk: relationship to daily and cumulative doses. Rheumatology (Oxford) 39: 1383–1389.

    Article  PubMed  Google Scholar 

  • Vane JR (1971) Inhibition of prostaglandin synthesis as a mechanism of action for aspirin-like drugs. Nature 231: 232

    Google Scholar 

  • Vane JR (1998) Differential inhibition of cyclooxygenase isoforms: An explanation of the action of NSAIDs. J Clin Rheumatol 4: S3

    Article  Google Scholar 

  • Vilar MJ, Cury SE, Ferraz MB, Sesso R, Atra E (1997) Renal abnormalities in ankylosing spondylitis. Scand J Rheumatol 26: 19–23

    PubMed  Google Scholar 

  • Ward MM (1999) Health-related quality of life in ankylosing spondylitis: a survey of 175 patients. Arthritis Care Res 12: 247–255

    Article  PubMed  Google Scholar 

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Hermann, J. (2005). Analgetika, nicht-steroidale Antirheumatika, Glucocorticoide. In: Felkenbach, A. (eds) Morbus Bechterew. Springer, Vienna. https://doi.org/10.1007/3-211-26646-1_24

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