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Role of Platelet-Activating Factor in Parturition

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Platelet-Activating Factor and Related Lipid Mediators 2

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 416))

Abstract

Platelet activating factor (PAF) has been implicated in a number of processes in reproductive biology including the synthesis and release of PAF by human spermatozoa,1 enhancement of sperm motility,2 ovulation4,5 and penetration into the oocyte. PAF has also been detected in the uterine tissue of a number of species6,7 and PAF receptors have been identified in endometrium,8 and myometrium.9 The relationship of PAF to implantation has received special attention. O’Neill and colleagues first reported10 that PAF was secreted by the embryo (for review see11) and that the implantation rate was increased in proportion to the PAF secreted into the media. A positive correlation was found also between the pregnancy outcome and PAF secretion by the embryo.11,12

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Author information

Author notes

  1. Hisashi Narahara

    Present address: Department of Ob/Gyn, Oita Medical University, 1-Hazama-cho, Oita-gun, Oita, 879-55, Japan

  2. Kiwamu Toyoshima

    Present address: Department of Ob-Gyn, Keio University, Tokyo, Japan

Authors and Affiliations

  1. Departments of Biochemistry and Obstetrics-Gynecology and The Cecil H. and Ida Green Center for Reproductive Biology Sciences Southwestern Medical Center at Dallas, The University of Texas, 5323 Harry Hines Boulevard, Dallas, Texas, 75235-9051, USA

    Hisashi Narahara, Kiwamu Toyoshima & John M. Johnston

Authors
  1. Hisashi Narahara
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  2. Kiwamu Toyoshima
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  3. John M. Johnston
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Editors and Affiliations

  1. Free University Berlin, Berlin, Germany

    Santosh Nigam  & Gert Kunkel  & 

  2. University of Utah, Salt Lake City, Utah, USA

    Stephen M. Prescott

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© 1996 Springer Science+Business Media New York

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Narahara, H., Toyoshima, K., Johnston, J.M. (1996). Role of Platelet-Activating Factor in Parturition. In: Nigam, S., Kunkel, G., Prescott, S.M. (eds) Platelet-Activating Factor and Related Lipid Mediators 2. Advances in Experimental Medicine and Biology, vol 416. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-0179-8_44

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  • DOI: https://doi.org/10.1007/978-1-4899-0179-8_44

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4899-0181-1

  • Online ISBN: 978-1-4899-0179-8

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