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Normal bone

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Biopsy of Bone in Internal Medicine: An Atlas and Sourcebook

Part of the book series: Current Histopathology ((CUHI,volume 21))

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Abstract

Bone, as other connective tissues, consists of cells, fibres and ground substance. But unlike the others, the major part of its extracellular compartment is calcified thus converting it into an extremely hard, rigid structure, ideally suited for its supportive, locomotive and protective functions. The skeleton maintains the shape of the body while protecting soft vital organs in the cranial and thoracic cavities. The skeleton also protects and constitutes the framework and part of the microenvironment for the haematopoietic tissue – the blood-forming elements of the bone marrow. It provides facilities for the attachment of the tendons and muscles required for locomotion. In addition to these mechanical functions, the skeleton is the body’s major depot for minerals and the regulator of their homeostasis: over 99% of the total body calcium is stored in the skeleton 1.4.12,17,54,134.137,150.

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Authors and Affiliations

  1. Department of Internal Medicine III, Unit for Bone and Bone Marrow Diagnosis, Germany

    R. Bartl

  2. Klinikum Großhadern, University of Munich, Germany

    R. Bartl

  3. Department of Hematology, Chaim Sheba Medical Center, Tel-Hashomer, Israel

    B. Frisch

  4. Sackler School of Medicine, Tel-Aviv University, Israel

    B. Frisch

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  1. R. Bartl
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© 1993 R. Bartl and B. Frisch

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Bartl, R., Frisch, B. (1993). Normal bone. In: Biopsy of Bone in Internal Medicine: An Atlas and Sourcebook. Current Histopathology, vol 21. Springer, Dordrecht. https://doi.org/10.1007/978-94-011-2222-1_2

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  • DOI: https://doi.org/10.1007/978-94-011-2222-1_2

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-010-4985-6

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