Zusammenfassung
Viele der derzeit gültigen Therapiestandards empfehlen in der Behandlung psychischer Erkrankungen nachdrücklich eine Monotherapie. In der klinischen Praxis werden jedoch in der Depressionsbehandlung mehr oder weniger häufig Kombinations- oder Augmentationsbehandlungen durchgeführt. Eine internationale, konsentierte Definition existiert bislang nicht, sodass nachfolgend eine Kombination als die gleichzeitige Verordnung von zwei oder mehreren Antidepressiva von einer Augmentation als der simultanen Verordnung eines Antidepressivums mit einem oder mehreren (Psycho-)Pharmaka einer anderen Kategorie unterschieden wird. In diesem Beitrag sollen die wesentlichen Kombinations- und Augmentationsstrategien bei depressiven Erkrankungen dargestellt werden.
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Schmauß, M., Messer, T. (2016). Behandlung depressiver Störungen. In: Messer, T., Schmauß, M. (eds) Polypharmazie in der Behandlung psychischer Erkrankungen. Springer, Vienna. https://doi.org/10.1007/978-3-7091-1849-8_1
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