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Antiepileptika

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Arzneiverordnungs-Report 2020

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Literatur

  • Baftiu A, Johannessen Landmark C, Rusten IR, Feet SA, Johannessen SI, Larsson PG (2016) Changes in utilisation of antiepileptic drugs in epilepsy and non-epilepsy disorders – a pharmacoepidemiological study and clinical implications. Eur J Clin Pharmacol 72:1245–1254

    Article  CAS  PubMed  Google Scholar 

  • Ben-Menachem E, Biton V, Jatuzis D, Abou-Khalil B, Doty P, Rudd GD (2007) Efficacy and safety of oral lacosamide as adjunctive therapy in adults with partial-onset seizures. Epilepsia 48:1308–1317

    Article  CAS  PubMed  Google Scholar 

  • Beydoun A (1999) Monotherapy trials with gabapentin for partial epilepsy. Epilepsia 40(Suppl 6):S13–S16

    Article  CAS  PubMed  Google Scholar 

  • Bresnahan R, Panebianco M, Marson AG (2019) Brivaracetam add-on therapy for drug-resistant epilepsy. Cochrane Database Syst Rev 3:CD11501. https://doi.org/10.1002/14651858.CD011501.pub2

    Article  PubMed  Google Scholar 

  • Brodie MJ (2004) Pregabalin as adjunctive therapy for partial seizures. Epilepsia 45(Suppl 6):19–27

    Article  CAS  PubMed  Google Scholar 

  • Brodie MJ, Perucca E, Ryvlin P, Ben-Menachem E, Meencke HJ (2007) Comparison of levetiracetam and controlled-release carbamazepine in newly diagnosed epilepsy. Baillieres Clin Neurol 68:402–408

    CAS  Google Scholar 

  • Costa J, Fareleira F, Ascenção R, Borges M, Sampaio C, Vaz-Carneiro A (2011) Clinical comparability of the new antiepileptic drugs in refractory partial epilepsy: a systematic review and meta-analysis. Epilepsia 52:1280–1291

    Article  PubMed  Google Scholar 

  • Deutsche Gesellschaft für Neurologie (2017) Leitlinien für Diagnostik und Therapie in der Neurologie. Erster epileptischer Anfall und Epilepsien im Erwachsenenalter. www.dgn.org/leitlinien

  • Dooley M, Plosker GL (2000) Levetiracetam. A review of its adjunctive use in the management of partial onset seizures. Drugs 60:871–893

    Article  CAS  PubMed  Google Scholar 

  • Finnerup NB, Attal N, Haroutounian S, McNicol E, Baron R, Dworkin RH, Gilron I, Haanpää M, Hansson P, Jensen TS, Kamerman PR, Lund K, Moore A, Raja SN, Rice AS, Rowbotham M, Sena E, Siddall P, Smith BH, Wallace M (2015) Pharmacotherapy for neuropathic pain in adults: a systematic review and meta-analysis. Lancet Neurol 14:162–173

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Gabapentin Diabetic Neuropathy Study Group, Backonja M, Beydoun A, Edwards KR, Schwartz SL, Fonseca V, Hes M, et al for the Gabapentin Diabetic Neuropathy Study Group (1998) Gabapentin for the symptomatic treatment of painful neuropathy in patients with diabetes mellitus. JAMA 280:1831–1836

    Article  Google Scholar 

  • Goa KL, Ross SR, Chrisp P (1993) Lamotrigine. A review of its pharmacological properties and clinical efficacy in epilepsy. Drugs 46:152–176

    Article  CAS  PubMed  Google Scholar 

  • Hitiris N, Brodie MJ (2006) Modern antiepileptic drugs: guidelines and beyond. Curr Opin Neurol 19:175–180

    PubMed  Google Scholar 

  • Kanner AM, Ashman E, Gloss D, Harden C, Bourgeois B, Bautista JF, Abou-Khalil B, Burakgazi-Dalkilic E, Llanas Park E, Stern J, Hirtz D, Nespeca M, Gidal B, Faught E, French J (2018) Practice guideline update summary: efficacy and tolerability of the new antiepileptic drugs I: treatment of new-onset epilepsy: report of the guideline development, dissemination, and implementation subcommittee of the American academy of neurology and the American epilepsy society. Neurology 91:74–81

    Article  CAS  PubMed  Google Scholar 

  • Koch MW, Polman SK (2009) Oxcarbazepine versus carbamazepine monotherapy for partial onset seizures. Cochrane Database Syst Rev 2009(4):CD6453

    Google Scholar 

  • LaRoche SM, Helmers SL (2004) The new antiepileptic drugs: scientific review. JAMA 291:605–614

    Article  CAS  PubMed  Google Scholar 

  • Lynch BA, Lambeng N, Nocka K, Kensel-Hammes P, Bajjalieh SM, Matagne A, Fuks B (2004) The synaptic vesicle protein SV2A is the binding site for the antiepileptic drug levetiracetam. PNAS 101:9861–9866

    Article  CAS  PubMed  Google Scholar 

  • Marson AG, Al-Kharusi AM, Alwaidh M, Appleton R, Baker GA, Chadwick DW, Cramp C, Cockerell OC, Cooper PN, Doughty J, Eaton B, Gamble C, Goulding PJ, Howell SJL, Hughes A, Jackson M, Jacoby A, Kellett M, Lawson GR, Leach JP, Nicolaides P, Roberts R, Shackley P, Shen J, Smith DS, Smith PEM, Tudor Smith C, Vanoli A, Williamson PR, SANAD Study group (2007a) The SANAD study of effectiveness of carbamazepine, gabapentin, lamotrigine, oxcarbazepine, or topiramate for treatment of partial epilepsy: an unblinded randomised controlled trial. Lancet 369:1000–1015

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Marson AG, Al-Kharusi AM, Alwaidh M, Appleton R, Baker GA, Chadwick DW, Cramp C, Cockerell OC, Cooper PN, Doughty J, Eaton B, Gamble C, Goulding PJ, Howell SJL, Hughes A, Jackson M, Jacoby A, Kellett M, Lawson GR, Leach JP, Nicolaides P, Roberts R, Shackley P, Shen J, Smith DS, Smith PEM, Tudor Smith C, Vanoli A, Williamson PR, SANAD Study group (2007b) The SANAD study of effectiveness of valproate, lamotrigine, or topiramate for generalized and unclassifiable epilepsy: an unblinded randomized controlled trial. Lancet 369:1016–1026

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Mbizvo GK, Dixon P, Hutton JL, Marson AG (2012) Levetiracetam add-on for drug-resistant focal epilepsy: an updated Cochrane Review. Cochrane Database Syst Rev 9:CD1901

    Google Scholar 

  • Moore RA, Straube S, Wiffen PJ, Derry S, McQuay HJ (2009) Pregabalin for acute and chronic pain in adults. Cochrane Database Syst Rev 2009(3):CD7076

    Google Scholar 

  • Morello CM, Leckband SG, Stoner CP, Moorhouse DF, Sahagian GA (1999) Randomized double-blind study comparing the efficacy of gabapentin with amitriptyline on diabetic peripheral neuropathy pain. Arch Intern Med 159:1931–1937

    Article  CAS  PubMed  Google Scholar 

  • National Institute for Health and Care Excellence (NICE) (2018) Epilepsies: the diagnosis and management. Clinical guideline CG137. https://www.nice.org.uk/guidance/cg137 (Erstellt: April 2018)

  • Nevitt SJ, Tudur Smith C, Weston J, Marson AG (2018) Lamotrigine versus carbamazepine monotherapy for epilepsy: an individual participant data review. Cochrane Database Syst Rev 6:CD1031

    PubMed  Google Scholar 

  • Nunes VD, Sawyer L, Neilson J, Sarri G, Cross JH (2013) Profile of lacosamide and its role in the long-term treatment of epilepsy: a perspective from the updated NICE guideline. Neuropsychiatr Dis Treat 9:467–476

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Perucca E, Yasothan U, Clincke G, Kirkpatrick P (2008) Lacosamide. Nat Rev Drug Discov 7:973–974

    Article  CAS  PubMed  Google Scholar 

  • Pulman J, Jette N, Dykeman J, Hemming K, Hutton JL, Marson AG (2014) Topiramate add-on for drug-resistant partial epilepsy. Cochrane Database Syst Rev 2:CD1417

    Google Scholar 

  • Stephen LJ, Brodie MJ (2017) Brivaracetam: a novel antiepileptic drug for focal-onset seizures. Ther Adv Neurol Disord 11:1756285617742081

    PubMed  PubMed Central  Google Scholar 

  • Thijs RD, Surges R, O’Brien TJ, Sander JW (2019) Epilepsy in adults. Lancet 393:689–701

    Article  PubMed  Google Scholar 

  • Tomson T, Battino D, Perucca E (2016) Valproic acid after five decades of use in epilepsy: time to reconsider the indications of a time-honoured drug. Lancet Neurol 15:210–218

    Article  CAS  PubMed  Google Scholar 

  • Veroniki AA, Cogo E, Rios P, Straus SE, Finkelstein Y, Kealey R, Reynen E, Soobiah C, Thavorn K, Hutton B, Hemmelgarn BR, Yazdi F, D’Souza J, MacDonald H, Tricco AC (2017) Comparative safety of anti-epileptic drugs during pregnancy: a systematic review and network meta-analysis of congenital malformations and prenatal outcomes. BMC Med 15(1):95

    Article  PubMed  PubMed Central  Google Scholar 

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Authors and Affiliations

  1. Pharmakologisches Institut der Universität Heidelberg, Im Neuenheimer Feld 366, 69120, Heidelberg, Deutschland

    Prof. em. Dr. med. Ulrich Schwabe

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  1. Prof. em. Dr. med. Ulrich Schwabe
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Correspondence to Ulrich Schwabe .

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Editors and Affiliations

  1. Pharmakologisches Institut, Universität Heidelberg, Heidelberg, Baden-Württemberg, Germany

    Ulrich Schwabe

  2. Arzneimittelkommission der deutschen Ärzteschaft, Berlin, Berlin, Germany

    Wolf-Dieter Ludwig

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Schwabe, U. (2020). Antiepileptika. In: Schwabe, U., Ludwig, WD. (eds) Arzneiverordnungs-Report 2020. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-62168-4_14

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  • DOI: https://doi.org/10.1007/978-3-662-62168-4_14

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