Zusammenfassung
Kopfschmerzen sind die häufigsten chronischen oder rezidivierenden Schmerzen im Kindes- und Jugendalter. Grundlage der Therapie ist eine Einteilung der Kopfschmerzen orientiert an internationalen Standards und einer nachvollziehbaren Phänomenologie. Die wichtigsten primären Kopfschmerzformen sind Spannungskopfschmerzen und Migräne, die im Kindesalter oft gemeinsam auftreten. Kinder und Jugendliche müssen diese beiden Kopfschmerzformen unterscheiden lernen, um bei Spannungskopfschmerzen Ablenkungsstrategien sowie bei Migräneattacken Analgetika einzusetzen. Psychologische und andere nichtmedikamentöse Verfahren helfen, die Häufigkeit von Kopfschmerzattacken zu reduzieren. Eine tägliche Einnahme von Prophylaktika ist in der Regel nicht indiziert. Analgetikainduzierte Kopfschmerzen kommen auch in der Pädiatrie vor, trigeminoautonome Kopfschmerzen sind sehr selten.
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Literatur
Abu-Arafeh I, Russel G (1994) Prevalence of headache and migraine in schoolchildren. BMJ 309: 765–769
Almeida DB, Cunali PA, Santos HL, Brioschi M, Prandini M (2004) Chronic paroxysmal hemicrania in early childhood: case report. Cephalalgia 24: 608–609
Ambrosetto P, Nicolini F, Zoli M, Cirillo L, Feraco P, Bacci A (2014) Ophthalmoplegic migraine: From questions to answers. Cephalalgia 34: 914–919
Ambrosiani PJ (2000) A review of pharmacotherapy of major depression in children and adolescents. Psychiatr Serv 51: 627–633
Amin FM, Asghar MS, Hougaard A, Hansen AE, Larsen VA, de Koning PJ, Larsson HB, Olesen J, Ashina M (2013) Magnetic resonance angiography of intracranial and extracranial arteries in patients with spontaneous migraine without aura: a cross-sectional study. Lancet Neurol 12: 454–461
Amin FM, Hougaard A, Schytz HW, Asghar MS, Lundholm E, Parvaiz AI, de Koning PJ, Andersen MR, Larsson HB, Fahrenkrug J, Olesen J, Ashina M (2014) Investigation of the pathophysiological mechanisms of migraine attacks induced by pituitary adenylate cyclase-activating polypeptide-38. Brain 137: 779–794
Antonaci F, Pareja JA, Caminero AB, Sjaastad O (1998) Chronic paroxysmal hemicrania and hemicrania continua. Parenteral indomethacin: the ’indotest’. Headache 38: 122–128
Antonaci F, Sjaastad O (1989) Chronic paroxysmal hemicrania (CPH): a review of the clinical manifestations. Headache 29: 648–656
Anttila P, Metsähonkala L, Sillanpää M (2006) Long-term trends in the incidence of headache in Finnish schoolchildren. Pediatrics 117: e1197–e1201
Anxionnat R, de Melo Neto JF, Bracard S, Lacour JC, Pinelli C, Civit T, Picard L (2003) Treatment of hemorrhagic intracranial dissections. Neurosurgery 53: 289–300
Arruda MA, Bigal ME (2012) Migraine and migraine subtypes in preadolescent children: Association with school performance. Neurology 79: 1881–1888
Avery RA (2014) Reference range of cerebrospinal fluid opening pressure in children: historical overview and current data. Neuropediatrics 45: 206–211
Bahra A, Gawel MJ, Hardebo JE, Millson D, Breen SA, Goadsby PJ (2000) Oral zolmitriptan is effective in the acute treatment of cluster headache. Neurology 54: 1832–1839
Bahra A, May A, Goadsby PJ (2002) Cluster headache. Neurology 58: 354–361
Bandell Hoekstra ENG Abu-Saad HH Passchier J Frederiks CM Feron FJ Knipschild P (2001) Prevalence and characteristics of headache in Dutch schoolchildren. Eur J Pain 5: 145–153
Bender MT, Pradilla G, James C, Raza S, Lim M, Carson BS (2011) Surgical treatment of pediatric trigeminal neuralgia: case series and review of the literature. Child’s Nervous System 27: 2123–2129
Bigal ME, Liberman JN, Lipton RB (2006) Age-dependent prevalence and clinical features of migraine. Neurology 67: 246
Blankenburg M, Dubbel G, Hechler T, Wamsler C, Zernikow B (2009) Paroxysmal hemicrania in children – symptoms, diagnostic criteria, therapy and outcome. Cephalalgia 29: 873–882
Boes CJ, Dodick DW (2002) Refining the clinical spectrum of chronic paroxysmal hemicrania: a review of 74 patients. Headache 42: 699–708
Boles RG (2011) High degree of efficacy in the treatment of cyclic vomiting syndrome with combined co-enzyme Q10, L-carnitine and amitriptyline, a case series. BMC Neurol 11: 102
Bonfert M, Straube A, Schroeder AS, Reilich P, Ebinger F, Heinen F (2013) Primary headache in children and adolescents: update on pharmacotherapy of migraine and tension-type headache. Neuropediatrics 44: 3–19
Bourgeois M, Aicardi J, Goutieres F (1993) Alternating hemiplegia of childhood. J Pediatr 122: 673–679
Breslau N, Davis GC (1992) Migraine, major depression and panic disorder: a prospective epidemiologic study of young adults. Cephalalgia 12: 85–90
Breslau N, Lipton R, Stewart W, Schultz LR, Welch KM (2003) Comorbidity of migraine and depression: Investigating potential etiology and prognosis. Neurology 60: 1308–1312
Brna P, Dooley J, Gordon K, Dewan T (2005) The prognosis of childhood headache: A 20-year follow-up. Arch Pediatr Adolesc Med 159: 1157–1160
Brna P, Gordon K, Dooley J (2008) Canadian adolescents with migraine: impaired health-related quality of life. J Child Neurol 23: 39–43
Broeske D, Lenn NJ, Cantos E (1993) Chronic paroxysmal hemicrania in a young child: Possible relation to ipsilateral occipital infarction. J Child Neurol 8: 235–236
Cady R, O‘Carroll P, Dexter K, Freitag F, Shade CL (2014) SumaRT/Nap vs naproxen sodium in treatment and disease modification of migraine: a pilot study. Headache 54: 67–79
Carson L, Lewis D, Tsou M, McGuire E, Surran B, Miller C, Vu TA (2011) Abdominal migraine: an under-diagnosed cause of recurrent abdominal pain in children. Headache 51: 707–712
Chiappedi M, Balottin U (2014) Medication overuse headache in children and adolescents. Curr Pain Headache Rep 18: 1–6
Cittadini E, Goadsby PJ (2006) Revisiting the International Headache Society criteria for paroxysmal hemicrania: A series of 21 patients. Cephalalgia 26: 1401–1402
Cohen AS, Goadsby PJ (2007) Paroxysmal hemicrania responding to topramate. J Neurol Neurosurg Psychiatry 78: 96–97
D‘Andrea G, Granella F (2001) SUNCT syndrome: the first case in childhood. Cephalalgia 21: 701–702
Derosier FJ, Lewis D, Hershey AD, Winner PK, Pearlman E, Rothner AD, Linder SL, Goodman DK, Jimenez TB, Granberry WK, Runken MC (2012) Randomized trial of sumatriptan and naproxen sodium combination in adolescent migraine. Pediatrics 129: e1411–e1420
El-Chammas K, Keyes J, Thompson N, Vijayakumar J, Becher D, Jackson JL (2013) Pharmacologic treatment of pediatric headaches: a meta-analysis. JAMA pediatrics 167: 250–258
Evans RW, Whyte C (2013) Cyclic vomiting syndrome and abdominal migraine in adults and children. Headache 53: 984–993
Evers S (2013) The Efficacy of Triptans in Childhood and Adolescence Migraine. Current Pain Headache Rep 17: 1–6
Evers S, Husstedt IW (1996) Alternatives in drug treatment of chronic paroxysmal hemicrania. Headache 36: 429–432
Evers S, Marziniak M (2010) Clinical features, pathophysiology, and treatment of medication-overuse headache. Lancet Neurol 9: 391–401
Evers S, Kropp P, Pothmann R, Heinen F, Ebinger F (2008) Therapie idiopathischer Kopfschmerzen im Kindes- und Jugendalter. Revidierte Empfehlungen der Deutschen Migräne- und Kopfschmerzgesellschaft (DMKG) und der Gesellschaft für Neuropädiatrie (GNP). Nervenheilkunde 27: 1127–1137
Evers S, Paulus W, Richter HP (2003) Trigeminusneuralgie. Leitlinien für Diagnostik und Therapie in der Neurologie. Thieme, Stuttgart, S 341–346
Evers S, Pothmann R, Überall MA, Naumann E, Gerber W-D (2002) Therapie idiopathischer Kopfschmerzen im Kindesalter. Empfehlungen der Deutschen Migräne- und Kopfschmerzgesellschaft (DMKG). Schmerz 16: 48–56
Förderreuther S, Evers S, Paulus W, Richter HP (2003) Trigeminusneuralgie. Leitlinien für Diagnostik und Therapie in der Neurologie. Thieme, Stuttgart, S 341–346
Gatzonis S, Mitsikostas DD, Ilias A, Zournas CH, Papageorgiou C (1996) Two more secondary headaches mimicking chronic paroxysmal hemicrania. Is this the exception or the rule? Headache 36: 511–513
Gelfand AA, Goadsby PJ (2012) Primary sex headache in adolescents. Pediatrics 130: e439–e441
Gherpelli JLD, Nagae Poetscher LMN, Souza AMMH, Bosse EMB, Rabello GD, Diament A, Scaff M (1998) Migraine in childhood and adolescence. A critical study of the diagnostic criteria and of the influence of age on clinical findings. Cephalalgia 18: 333–341
Giffin NJ, Ruggiero L, Lipton RB, Silberstein SD, Tvedskov JF, Olesen J, Altman J, Goadsby PJ, Macrae A (2003) Premonitory symptoms in migraine: An electronic diary study. Neurology 60: 935–940
Gladstein J, Holden EW, Peralta L (1994) Chronic paroxysmal hemicrania in a child. Headache 34: 519–520
Goadsby PJ (1999) Chronic tension-type headache: where are we? Brain 122: 1611–1612
Goadsby PJ (2005) Trigeminal autonomic cephalalgias: Fancy term or constructive change to the IHS classification? J Neurol Neurosurg Psychiatry 76: 301–305
Goadsby PJ, Edvinsson L (1994) Human in vivo evidence for trigeminovascular activation in cluster headache. Neuropeptide changes and effects of acute attacks therapies. Brain 117: 427–434
Goadsby PJ, Lipton RB (1997) A review of paroxysmal hemicranias, SUNCT syndrome and other short-lasting headaches with autonomic feature, including new cases. Brain 120: 193–209
Göbel H (2012) Die Kopfschmerzen. Ursachen, Mechanismen, Diagnostik und Therapie in der Praxis. Springer, Heidelberg
International Headache Society (IHS); Headache Classification Committee (2013) The International Classification of Headache Disorder, 3rd Edition (beta version). Cephalgia 33: 629–808
Hershey AD, Powers SW, Bentti AL, de Grauw TJ (2000) Effectiveness of amitriptyline in the prophylactic management of childhood headaches. Headache 40: 539–549
Hershey AD, Winner P, Kabbouche MA, Gladstein J, Yonker M, Lewis D, Pearlman E, Linder SL, Rothner AD, Powers SW (2005) Use of the ICHD-II criteria in the diagnosis of pediatric migraine. Headache 45: 1288–1297
Ilik F, Ilik K (2014) Alice in Wonderland syndrome as aura of migraine. Neurocase 20: 474–475
Jensen TS, Rasmussen P, Reske-Nielsen E (1982) Association of trigeminal neuralgia with multiple sclerosis: clinical and pathological features. Acta Neurol Scand 65: 182–189
Jonsson P, Jakobsson A, Hensing G, Linde M, Moore CD, Hedenrud T (2013) Holding on to the indispensable medication - a grounded theory on medication use from the perspective of persons with medication overuse headache. J Headache Pain 14: 1–11
Katusic S, Beard CM, Bergstralh E, Kurland LT (1990) Incidence and clinical features of trigeminal neuralgia, Rochester, Minnesota, 1945-1984. Ann Neurol 27: 89–95
Khan OA (1998) Gabapentin relieves trigeminal neuralgia in multiple sclerosis patients. Neurology 51: 611–614
King S, Chambers CT, Huguet A, MacNevin RC, McGrath PJ, Parker L, MacDonald AJ (2011) The epidemiology of chronic pain in children and adolescents revisited: a systematic review. Pain 152: 2729–2738
Kirk S (2008) Transitions in the lives of young people with complex healthcare needs. Child: Care Health Dev 34: 567–575
Kors EE, Vanmolkot KRJ, Haan J, Frants RR, van den Maagdenberg AMJM, Ferrari MD (2004) Recent findings in headache genetics. Curr Opin Neurol 17: 283–288
Kröner-Herwig B, Heinrich M, Morris L (2007) Headache in German children and adolescents: A population-based epidemiological study. Cephalalgia 27: 519–527
Kudrow DB, Kudrow L (1989) Successful aspirin prophylaxis in a child with chronic paroxysmal hemicrania. Headache 29: 280–281
Larsson B (1999) Recurrent headaches in children and adolescents. In: McGrath PJ, Finley GA (eds) Chronic and recurrent pain in children and adolescents, 13th ed. IASP Press, Seattle, pp 115–139
Laurell K, Larsson B, Eeg-Olofsson O (2004) Prevalence of headache in Swedish schoolchildren, with a focus on tension-type headache. Cephalalgia 24: 380–388
Lee LY, Abbott L, Mahlangu B, Moodie SJ, Anderson S (2012) The management of cyclic vomiting syndrome: a systematic review. Eur J Gastroenterol Heptal 24: 1001–1006
Lendvai D, Verdecchia P, Crenca R, Redondi A, Braccili T, Turri E, Lucarelli S (1999) Fever: a novelty among the symptoms accompanying migraine attacks in children. Eur Rev Med Pharmacol Sci 3: 229–232
Leniger T, Diener HC, Hufnagel A (2003) Erhöhte zerebrale Erregbarkeit und "spreading depression" Ursachen für eine Komorbidität von Epilepsie und Migräne? Nervenarzt 74: 869–874
Lewis DW, Ashwal S, Dahl G, Dorbad D, Hirtz D, Prensky A, Jarjour I; Quality Standards Subcommittee of the American Academy of Neurology; Practice Committee of the Child Neurology Society (2002) Practice parameter: evaluation of children and adolescents with recurrent headaches: report of the Quality Standards Subcommittee of the American Academy of Neurology and the Practice Committee of the Child Neurology Society. Neurology 59: 490–498
Lewis DW, Gozzo YF, Avner MT (2005) The "other" primary headaches in children and adolescents. Pediatr Neurol 33: 303–313
Lin KY, Hsu YS, Young YH (2010) Brainstem lesion in benign paroxysmal vertigo children: evaluated by a combined ocular and cervical vestibular-evoked myogenic potential test. Int J Pediatr Otorhinolaryngol 74: 523–527
Lipton RB, Manack A, Ricci JA, Chee E, Turkel CC, Winner P (2011) Prevalence and Burden of Chronic Migraine in Adolescents: Results of the Chronic Daily Headache in Adolescents Study (C-dAS). Headache 51: 693–706
Love S, Coakham HB (2001) Trigeminal neuralgia: Pathology and pathogenesis. Brain 124: 2347–2360
Ludvigsson J (1974) Propranolol used in prophylaxis of migraine in children. Acta Neurol Scand 50: 109–115
Luntamo T, Sourander A, Santalahti P, Aromaa M, Helenius H (2012) Prevalence changes of pain, sleep problems and fatigue among 8-year-old children: Years 1989, 1999, and 2005. J Pediatr Psychol 37: 307–318
Mar S, Kelly JE, Isbell S, Aung WY, Lenox J, Prensky A (2013) Prevalence of white matter lesions and stroke in children with migraine. Neurology 81: 1387–1391
Mariani R, Capuano A, Torriero R, Tarantino S, Properzi E, Vigevano F, Valeriani M (2014) Cluster headache in childhood: case series from a pediatric headache center. J Child Neurol 29: 62–65
Matharu MS, Cohen AS, Frackowiak RS, Goadsby PJ (2006) Posterior hypothalamic activation in paroxysmal hemicrania. Ann Neurol 59: 535–545
May A (2012) Clusterkopfschmerz und trigeminoautonome Kopfschmerzen. In: Diener HC, Weimar C (Hrsg) Leitlinien für Diagnostik und Therapie in der Neurologie. Herausgegeben von der Kommission „Leitlinien“ der Deutschen Gesellschaft für Neurologie. Thieme, Stuttgart
May A, Pageler L (2003) Trigeminoautonomer Kopfschmerz. In: Diener H-C (Hrsg) Kopfschmerzen. Thieme, Stuttgart, New York, S 74–81
May A, Evers S, Straube A, Pfaffenrath V, Diener HC (2005) Therapie und Prophylaxe von Cluster-Kopfschmerzen und anderen trigemino-autonomen Kopfschmerzen. Schmerz 19: 225–241
May A, Leone M, Afra J, Linde M, Sandor PS, Evers S, Goadsby PJ; EFNS Task Force (2006) EFNS guideline on the treatment of cluster headache and other trigeminal-autonomic cephalalgias. Eur J Neurol 13: 1066–1077
McGrath PA (2001) Chronic daily headache in children and adolescents. Current Pain and Headache Reports 5: 557–566
Metsahonkala L, Sillanpaa M, Tuominen J (1998) Social environment and headache in 8- to 9-year-old children: A follow-up study. Headache 38: 222–228
Mohamed BP, Goadsby PJ, Prabhakar P (2012) Safety and efficacy of flunarizine in childhood migraine: 11 years‘ experience, with emphasis on its effect in hemiplegic migraine. Dev Med Child Neurol 54: 274–277
Moorjani BI, Rothner AD (2001) Indomethacin-responsive headaches in children and adolescents. Semin Pediatr Neurol 8: 40–45
Mortimer MJ, Kay J, Jaron A (1992) Epidemiology of headache and childhood migraine in an urban general practice using Ad Hoc, Vahlquist and IHS criteria. Dev Med Child Neurol 34: 1095–1101
Olesen J, Steiner TJ (2004) The international classification of headache disorders, 2nd edn (ICDH-II). J Neurol Neurosurg Psychiatry 75: 808–811
Paulus W, Evers S, May A, Steude U, Wolowski A, Pfaffenrath V (2003) Therapie und Prophylaxe von Gesichtsneuralgien und anderen Formen der Gesichtsschmerzen. Schmerz 17: 74–91
Peiris JB, Perera GL, Devendra SV, Lionel ND (1980) Sodium valproate in trigeminal neuralgia. Med J Aust 2: 278
Pfefferbaum B, Hagberg CA (1993) Pharmacological management of pain in children. J Am Acad Child Adolesc Psychiatry 32: 235–242
Piazza F, Chiappedi M, Maffioletti E, Galli F, Balottin U (2012) Medication Overuse Headache in School-Aged Children: More Common Than Expected? Headache 52: 1506–1510
Powers SW, Patton SR, Hommel KA, Hershey AD (2003) Quality of life in childhood migraine: Clinical impact and comparison to other chronic illnesses. Pediatrics 112: e0–e6
Raieli V, Eliseo M, Pandolfi E, La Vecchia M, La Franca G, Puma D, Ragusa D (2005) Recurrent and chronic headaches in children below 6 years of age. J Headache Pain 6: 135–142
Ralli G, Atturo F, de Filippis C (2009) Idiopathic benign paroxysmal vertigo in children, a migraine precursor. Int J Pediatr Otorhinolaryngol 73: S16–S18
Raskin NH (1988) The indomethacin-responsive syndromes. In: Raskin NH (ed) Headache. 2 ed. Churchill Livingstone, New York, pp 255–268
Reale L, Guarnera M, Grillo C, Maiolino L, Ruta L, Mazzone L (2011) Psychological assessment in children and adolescents with Benign Paroxysmal Vertigo. Brain Dev 33: 125–130
Romanello S, Spiri D, Marcuzzi E, Zanin A, Boizeau P, Riviere S, Vizeneux A, Moretti R, Carbajal R, Mercier JC, Wood C, Zuccotti GV, Crichiutti G, Alberti C, Titomanlio L (2013) Association between childhood migraine and history of infantile colic. JAMA 309: 1607–1612
Russell MB, Ducros A (2011) Sporadic and familial hemiplegic migraine: pathophysiological mechanisms, clinical characteristics, diagnosis, and management. Lancet Neurol 10: 457–470
Russell MB, Ostergaard S, Bendtsen L, Olesen J (1999) Familial occurrence of chronic tension-type headache. Cephalalgia 19: 207–210
Sanchezdelrio M, Reuter U (2004) Migraine aura: new information on underlying mechanisms. Curr Opin Neurol 17: 289–293
Schürmann S (2005) Erste interdisziplinäre, klinikgestützte Kinderschmerzambulanz in Deutschland. Symposium Medical 9: 20–24
Sekhara T, Pelc K, Mewasingh LD, Boucquey D, Dan B (2005) Pediatric SUNCT Syndrome. Pediatr Neurol 33: 206–207
Shabbir N, McAbee G (1994) Adolescent chronic paroxysmal hemicrania responsive to verapamil monotherapy. Headache 34: 209–210
Sillanpää M, Anttila P (1996) Increasing prevalence of headache in 7-year-old schoolchildren. Headache 36: 466–470
Sist T, Filadora V, Miner M, Lema M (1997) Gabapentin for idiopathic trigeminal neuralgia: Report of two cases. Neurology 48: 1467
Sjaastad O, Antonaci F (1995) A piroxicam derivative partly effective in chronic paroxysmal hemicrania and hemicrania continua. Headache 35: 549–550
Soee AB, Skov L, Skovgaard LT, Thomsen LL (2013) Headache in children: Effectiveness of multidisciplinary treatment in a tertiary paediatric headache clinic. Cephalalgia 33: 1218–1228
Solaro C, Messmer Uccelli M, Uccelli A, Leandri M, Mancardi GL (2000) Low-dose gabapentin combined with either lamotrigine or carbamazepine can be useful therapies for trigeminal neuralgia in multiple sclerosis. Eur Neurol 44: 45–48
Solomon S, Newman LC (1995) Chronic paroxysmal hemicrania in a child? Headache 35: 234
Sprenger T, Valet M, Hammes M, Erhard P, Berthele A, Conrad B, Tolle TR (2004) Hypothalamic activation in trigeminal autonomic cephalgia: Functional imaging of an atypical case. Cephalalgia 24: 753–757
Stang PE (1992) Incidence of migraine headache: a population-based study in Olmsted County, Minnesota. Neurology 42: 1657–1662
Taha JM, Tew Jr JM (1996) Comparison of Surgical Treatments for Trigeminal Neuralgia: Reevaluation of Radiofrequency Rhizotomy. Neurosurgery 38: 865
Talvik I, Koch K, Kolk A, Talvik T (2006) Chronic paroxysmal hemicrania in a 3-year, 10-month-old female. Pediatr Neurol 34: 225–227
Trucco M, Mainardi F, Maggioni F, Badino R, Zanchin G (2004) Chronic paroxysmal hemicrania, hemicrania continua and SUNCT syndrome in association with other pathologies: A review. Cephalalgia 24: 173–184
Überall MA (1999) Zeitgemäße Migränetherapie bei Kindern. Schmerz 13: 97–98
Überall M, Wenzel D (1999) Intranasal sumatriptan for the acute treatment of migraine in children. Neurology 52: 1507–1510
Victorio MC, Rothner AD (2013) Diagnosis and treatment of idiopathic intracranial hypertension (IIH) in children and adolescents. Curr Neurol Neurosci Rep 13: 1–7
Viera JP, Salfuiero AB, Alfaro M (2006) Short lasting headache in children. Cephalalgia 26: 1220–1224
Vijayan N (1992) Symptomatic chronic paroxysmal hemicrania. Cephalalgia 12: 111–113
Wager J, Hirschfeld G, Zernikow B (2013) Tension-type headache or migraine? Adolescents’ pain descriptions are of little help. Headache 53: 322–332
Wang QP, Bai M (2011) Topiramate versus carbamazepine for the treatment of classical trigeminal neuralgia: a meta-analysis. CNS Drugs 25: 847–857
Wiffen P, Collins S, McQuay H, Carroll D, Jadad A, Moore A (2005) Anticonvulsant drugs for acute and chronic pain. Cochrane database of systematic reviews (Online): CD001133
Winner P (1999) Pediatric headaches: What`s new? Curr Opin Neurol 12: 269–272
Winner P, Lewis DW (eds) (2005) Young adult and pediatric headache management. BC Decker Inc, Hamilton
Winner P, Powers SW, Kabbouche MA, Hershey AD (2007) Diagnosing and managing headache in children. Curr Treat Options Neurol 9: 3–13
Zakrzewska JM, Chaudry Z, Nurmikko TJ, Patton DW, Mullens EL (1997) Lamotrigine (Lamictal) in refractory trigeminal neuralgia: results from a double-blind placebo controlled crossover trial. Pain 73: 223–230
Zernikow B, Wager J, Hechler T, Hasan C, Rohr U, Dobe M, Meyer A, Hübner-Möhler B, Wamsler C, Blankenburg M (2012) Characteristics of highly impaired children with severe chronic pain: a 5-year retrospective study on 2249 pediatric pain patients. BMC Pediatrics 12: 54
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Zernikow, B., Blankenburg, M., Überall, M. (2015). Kopfschmerztherapie. In: Zernikow, B. (eds) Schmerztherapie bei Kindern, Jugendlichen und jungen Erwachsenen. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-45057-4_14
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