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O2-Bilanz, O2-Transport, O2-Verbrauch, gemischtvenöse O2-Sättigung

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Monitoring in Anästhesie und Intensivmedizin
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Zusammenfassung

Die wesentliche Aufgabe des kardiozirkulatorischen Systems erfüllt sich in der angemessenen Versorgung der Organsysteme mit Sauerstoff und Substraten zur Sicherung des physiologischerweise statthabenden aeroben Metabolismus und in der Beseitigung von Metaboliten. Jedes hämodynamische Monitoring muß deshalb unter dem Gesichtspunkt eingeschätzt werden, in welchem Umfang es über die entscheidenden, zu optimierenden Größen beim Patienten Auskunft gibt, nämlich den konvektiven O 2 -Transport zum Gewebe (das globale O2-Angebot) und die Gewebeoxygenierung. Im Idealfall müßte bettseitig jederzeit eine Einschätzung des bioenergetischen Status der Zellen des Organismus möglich sein. In praxi sind jedoch mit dem verfügbaren hämodynamischen Monitoring (Pulmonal-arterieneinschwemmkatheter nach Swan-Ganz) unter klinischen Bedingungen selbst das O2-Angebot und der O2-Verbrauch nicht leicht zu erhalten, die stets nur eine indirekte Abschätzung der zellulären O2-Versorgung ermöglichen, da diese Größen aus Bestimmungen des Herzminutenvolumens (QT) und des arteriellen (CaO2) sowie gemischtvenösen (CvO2) O2-Gehaltes berechnet werden müssen.

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Literatur

  1. Bihari D, Smithies M, Gimson A, Tinker J (1987) The effects of vasodilatation with prostacyclin on oxygen delivery and uptake in critically ill patients. New Engl J Med 317: 397–403

    Article  CAS  PubMed  Google Scholar 

  2. Bishop JM, Donald KW, Wade OL (1954) Minute to minute changes in cardiac output by the direct Fick method in normal subjects during exercise and recovery. J Physiol 123: 233–241

    Google Scholar 

  3. Bishop JM, Wade OL, Donald KW (1958) Changes in jugular and renal arterio-venous oxygen content difference during exercise in heart disease. Clin Sci 17: 611–627

    CAS  PubMed  Google Scholar 

  4. Cain SM (1989) Supply dependency of oxygen uptake. In: Reinhart K, Eyrich K (eds) Clinical aspects of O2 transport and tissue oxygenation. Springer, Berlin Heidelberg New York Tokyo, pp 80–91

    Google Scholar 

  5. Dahn MS, Lange MP, Jacobs LA (1988) Central mixed and splanchnic venous oxygen saturation monitoring. Intensive Care Med 14: 373–376

    Article  CAS  PubMed  Google Scholar 

  6. Forsyth RP, Hoffbrand BM, Melmon KL (1970) Redistribution of cardiac output during hemorrhage in the unanesthetized monkey. Circ Res 27: 311–316

    Article  CAS  PubMed  Google Scholar 

  7. Gutierrez G, Pohil RJ (1987) Assessment of hypoxia by magnetic resonance spectroscopy and positron emission tomography. In: Bryan Brown CW, Ayre SM (eds) Oxygen transport and utilization. New Horizons, SCCM, Fullerton Calif USA, pp 171–214

    Google Scholar 

  8. Gutierrez G, Palizas F, Doglio G et al. (1992) Gastric intramucosal pH as a therapeutic index of tissue oxygenation in critically ill patients. Lancet 339: 195–199

    Article  CAS  PubMed  Google Scholar 

  9. Hannemann L, Meier-Hellmann A, Reinhart K (1992) Regional blood flow in sepsis. Clin Intensive Care 3, 1: 28–31

    Google Scholar 

  10. Jamieson WRE, Turnbull KW, Larrieu AJ, Dodds WA, Allison JC, Tyers GFO(1982) Continuous monitoring of mixed venous oxygen saturation in cardiac surgery. Can J Surg 5: 538–543

    Google Scholar 

  11. Jöbsis FF (1977) Noninvasive infrared monitoring of cerebral and myocardial oxygen sufficiency and circulatory parameters. Science 198: 1264–1267

    Article  PubMed  Google Scholar 

  12. Jösbis-Vandervliet FF, Fos E, A Sugioka (1987) Monitoring of cerebral oxygenation and cytochrome aa3 redox state. Int Anesthesiol Clin 25: 209–214

    Article  Google Scholar 

  13. Miller MJ (1982) Tissue oxygenation in clinical medicine: a historical review. Anesth Analg 61: 527–535

    CAS  PubMed  Google Scholar 

  14. Muir AL, Kirby B J, King AJ, Miller HC (1971) Mixed venous oxygen saturation in relation to cardiac-output in myocardial infarction. Br Med J 4: 276–278

    Article  Google Scholar 

  15. Pflüger E (1872) über die Diffusion des Sauerstoffs, den Ort und die Gesetze der Oxydationsprozesse im thierischen Organismus. Pflügers Arch Gesamte Physiol Menschen, Thiere 6: 43–63

    Article  Google Scholar 

  16. Reinhart K (1988) Zum Monitoring des Sauerstofftransportsystems. Anaesthesist 37: 1–9

    CAS  PubMed  Google Scholar 

  17. Reinhart K (1989) Monitoring of O2 transport and tissue oxygenation in critically ill patients. In: Reinhart K, Eyrich K (eds) Clinical aspects of 02 transport and tissue oxygenation. Springer, Berlin Heidelberg New York Tokyo, pp 195–211

    Google Scholar 

  18. Reinhart K, Kersting K, Föhring U, Schäfer M (1986) Can central-venous replace mixed-venous oxygen saturation measurements during anesthesia. Adv Exper Med Biol 200: 67–71

    Article  CAS  Google Scholar 

  19. Reinhart K, Bloos F, König F, Hannemann L, Kuss B (1989) Oxygen transport and muscle tissue oxygenation in hyperdynamic septic shock. Anesthesiology 71: A 379

    Google Scholar 

  20. Reinhart K, Föhring U, Kersting T, Schäfer M, Bredle D, Hirner A, Eyrich K (1989) Effects of thoracic epidural anesthesia on systemic hemodynamic function and systemic oxygen supply-demand relationship. Anesth Analg 69: 360–369

    Article  CAS  PubMed  Google Scholar 

  21. Reinhart K, Rudolph T, Bredle DL, Cain SM (1989) O2 uptake in bled dogs after resuscitation with hypertonic saline or hydroxyethylstarch. Am J Physiol 257: H238

    CAS  PubMed  Google Scholar 

  22. Reinhart K, Rudolph T, Bredle DL, Hannemann L, Cain SM (1989) Comparison of central venous to mixed venous oxygen saturation during changes in oxygen supply/ demand. Chest 195: 1216–1222

    Article  Google Scholar 

  23. Reinhart K, Schäfer M, Rudolph T, Specht M (1989) Mixed venous oxygen saturation. Appl Cardiopulm Pathophysiol 2: 315–325

    Google Scholar 

  24. Reinhart K, Specht M, Rudolph T (1989) Akutelle Aspekte der Oxymetrie. In: Lawin P, Peter K (Hrsg) Intensivmedizin 1989, Intensivmedizin, Notfallmedizin, Anaesthesio-logie. Thieme, Stuttgart, S 87–84

    Google Scholar 

  25. Rocha de AG, Edmonds JF, Williams WG, Parier C, Trusler GA (1978) Importance of mixed venous oxygen saturation in the care of critically ill patients. Can J Surg 21: 227–229

    PubMed  Google Scholar 

  26. Ronco JJ, Phang PT (1991) Validation of an indirect calorimeter to measure oxygen consumption in critically ill patients. J Crit Care 6: 36–41

    Article  Google Scholar 

  27. Ronco JJ, Fanwick JC, Wiggs BR (1993) Oxygen consumption is independent of increases in oxygen delivery by dobutamine in septic patients who have normal or increased plasma lactate. Am Rev Resp Dis 147: 25–31

    Article  CAS  PubMed  Google Scholar 

  28. Sibbald WJ , Bersten A, Rutledge FS (1989) The role of tissue hypoxia in multiple organ failure, In: Reinhart K, Eyrich K (eds) Clinical aspects of O2 transport and tissue oxygenation. Springer, Berlin Heidelberg New York pp 102–114

    Google Scholar 

  29. Specht M, Wichmann K, Apenburg C, Johnson RW, Reinhart K (1991) Continuous measurement of oxygen supply and oxygen consumption — first data on a new monitoring concept. Anesthesiology 753: A456

    Article  Google Scholar 

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© 1995 Springer-Verlag Berlin Heidelberg

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Reinhart, K., Hannemann, L. (1995). O2-Bilanz, O2-Transport, O2-Verbrauch, gemischtvenöse O2-Sättigung. In: List, W.F., Metzler, H., Pasch, T. (eds) Monitoring in Anästhesie und Intensivmedizin. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-08840-1_17

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  • DOI: https://doi.org/10.1007/978-3-662-08840-1_17

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-662-08841-8

  • Online ISBN: 978-3-662-08840-1

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