Skip to main content
SpringerLink
Log in

Monoaminergic Systems and Child Psychiatric Pathophysiology

  • Conference paper
Brain and Behavior in Child Psychiatry

Abstract

Since the demonstration in 1921 by Otto Loewi that a chemical substance was released after nervous stimulation, much neuroscientific research has been performed on neurotransmission and chemical synapse. Work in neuro- and psychopharmacology has permitted the comparison between notions of neurotransmission and neuropsychiatric syndromes.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 39.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  • Alpert M, Friedhoff AJ (1980) An un-dopamine hypothesis of schizophrenia. Schizophr Bull 6:387–390

    PubMed  CAS  Google Scholar 

  • Angrist B, Sathananthan G, Wilk S, Gershon S (1974) Amphetamine psychosis: behavioral and biochemical aspects. J Psychiatr Res 11:13–23

    Article  PubMed  CAS  Google Scholar 

  • Berger M, Müller W (1989) Psychologische Verlaufsuntersuchungen zur noradrenergen-cholinergen Imbalance—Hypothese affektiver Erkrankungen. Arbeits- und Ergebnisbericht des Sonderforschungsbereichs 258. University of Heidelberg, pp 1–62

    Google Scholar 

  • Besson JM and Tassin JP (1985) Les systèmes dopaminergiques et leurs récepteurs. Neuropsy 1:21–29

    Google Scholar 

  • Besson JM, Chaouch A, Chitour D (1987) Physiologie de la douleur. Encyl. Med. Chir. (Paris-France), Neurologie, 17003F10, 8P

    Google Scholar 

  • Bird ED, Spokes EG, Iversen LL (1980) Dopamine and noradrenaline in post-mortem brain in Huntington’s diesase and schizophrenic illness. Acta Psychiatr Scand Supplt 280 61:63–73

    CAS  Google Scholar 

  • Blundell JE (1984) Serotonin and appetite. Neuropharmacology 23:1537–1551

    Article  PubMed  CAS  Google Scholar 

  • Bruneau N, Garreau B, Barthélémy C, Martineau J, Muh J, Lelord G (1990) Clinical, electrophysiological, and biochemical markers and monoaminergic hypotheses in autism. This volume, pp 217–234

    Google Scholar 

  • Cohen DJ, Caparullo BK, Shaywitz BA and Bowers MB (1977) Dopamine and serotonin metabolism in neuropsychiatrically disturbed children. Arch Gen Psychiatry 34:534–537

    PubMed  CAS  Google Scholar 

  • Cohen DJ, Schaywitz BA, Caparulo B, Young JG and Bowers MB (1988) Chronic, multiple tics of Gilles dela Tourette’s disease: CSF acid monoamine metabolites after probenecid administration. Arch Gen Psychiatry 35:245–250

    Google Scholar 

  • Costall B, Naylor RJ (1979) Behavioral aspects of dopamine agonists and antagonists. In Horn AS, Korf J, Westerink BHC (eds) Neurobiology of dopamine. Academic Press Publ 31: 555–576

    Google Scholar 

  • Coyle JT (1985) Development of brain neurotransmitters and child psychiatry. In RF Hales and AJ Frances (eds) Annual review of the American Academy of Child Psychiatry, Vol. 4, Washington D.C., American Psychiatry Press

    Google Scholar 

  • Evrard Ph, Lyon G and Gadisseux JF (1984) Le développement prénatal du système nerveux et ses perturbations: les mécanismes généraux. In: Progrès en néonatologie. Karger, Basel, pp 63–69

    Google Scholar 

  • Filser JG, Spira J, Fischer M, Gattaz WF, Müller WE (1988) The evaluation of MHPG-sulfate as a possible marker of the central norepinephrine turnover. Studies in healthy volunteers and depressed patients. J Psychiatr Res 22:171–181

    Article  PubMed  CAS  Google Scholar 

  • Fuxe K (1978) Place de la dopamine dans les amines biogènes à fonction de neurotransmetteur. Triangle. J Sandoz Sci Méd 28:125–136

    Google Scholar 

  • Garfinkel PE, Warsh JJ, Stranger HC, Godse DD (1977) CNS monoamine metabolism in bipolar affective disorder. Evaluation using a peripheral decarboxylase inhibitor. Arch Gen Psychiatry 34:735–739

    PubMed  CAS  Google Scholar 

  • Gamier C, Barthélémy C, Garreau B, Jouve J, Muh JP and Lelord G (1983) Les anomalies des monoamines et de leurs enzymes dans l’autisme de l’enfant. L’encéphale, IX 3:201–261

    Google Scholar 

  • Garreau B, Barthélémy C, Bruneau N, Martineau J (1990) Sleep disturbances in children: from the physiological to the clinical. This volume, pp 317–342

    Google Scholar 

  • Gerner RH, Cohen DJ, Fairbanks L, Anderson GM, Young JG, Scheirin M, Linnoila M, Shaywitz BA, Hare TA (1984) CSF neurochemistry of women with anorexia nervosa and normal women. Am J Psychiatr 141:1441–1444

    PubMed  CAS  Google Scholar 

  • Hamon M (1981) Les systèmes sérotoninergiques corticaux. Séminaire de psychiatrie biologique, Hôpital Ste Anne 1:107–126

    Google Scholar 

  • Holmes GL (1986) Morphological and physiological maturation of the brain in the neonate and young children. J Clin Neurophysiol 3, 3:209–238

    Article  PubMed  CAS  Google Scholar 

  • Hosobuchi Y (1972) Tryptophan reversal of tolerance to analgesia induced by central gray stimulation. Lancet 2:47

    Google Scholar 

  • Hudson JI and Pope HG (1987) Newer antidepressants in the treatment of bulimia nervosa. Psych Pharmacology Bull 23:52–57

    CAS  Google Scholar 

  • Iversen SD (1984) 5-HT and anxiety. Neuropharmacology 23:1553–1560

    Article  PubMed  CAS  Google Scholar 

  • Jouvet M (1969) Biogenic amines and the states of sleep. Science 163:32–41

    Article  PubMed  CAS  Google Scholar 

  • Kaye WH, Ebert MH, Gwirtman HE, Weiss SR (1984) Differences in brain serotoninergic metabolism between nonbulimic and bulimic patients with anorexia nervosa. Am J Psychiatry 141:1598–1601

    PubMed  CAS  Google Scholar 

  • Langer SZ, Raisman R, Sechter D, Gay C, Loo H, Zarifian E (1984) 3H-Imipramine and 3H-desipramine binding sites in depression. In: Frontiers in biochemical and pharmacological research in depression. E Ushdin et al. (eds). Raven, New York, pp 113–125

    Google Scholar 

  • Launay JM, Pasques D, Dreux C (1983) Données nouvelles sur le métabolisme de la Sérotonine dans les plaquettes sanguines: modèles de neurones. Act Phar Biol Clin 2:155–159

    Google Scholar 

  • Laverty R (1978) Catecholamines: role in health and disease. Drugs 16:418–440

    Article  PubMed  CAS  Google Scholar 

  • Lichtensteiger W (1979) The neuroendocrinology of dopamine systems In: Horn AS, Korf J, Westerink BHC (eds). Neurobiology of dopamine. Academic, London New York San Francisco, pp491–521

    Google Scholar 

  • Lidberg L, Asberg M, Sunquist-Stensman UB (1984) 5-Hydroxyindolacetic acid levels in attempted suicides who have killed their children. Lancet 2:928

    Article  PubMed  CAS  Google Scholar 

  • Linnoila M, Virkkunen M, Scheinin M, Nuutila A, Rimon R, Goodwin FK (1983) Low cerebrospinal fluid 5-hydroxyindolcetic acid concentration differentiates impulsive from nonimpulsive violent behavior. Life Science 33:2609–2614

    Article  CAS  Google Scholar 

  • Lloyds KG (1978) Neurotransmitter interactions related to central dopamine neurons. Essays Neurochem Neuropharmacol 3:131–207

    Google Scholar 

  • Lyon G, Evrard Ph and Gadisseux JF (1984) Les anomalies du dévelopement du télencéphale human pendant la période cytogénèse-histogénèse. Progrès néonatalogie: 70–84

    Google Scholar 

  • Mac Kay AvP, Bird ED, Iversen LL, Spokes EC, Creese I, Snyder SH (1980) Dopaminergic abnormalities in post-mortem schizophrenic brain. Adv Biochem Psychopharmacol 24:325–333

    CAS  Google Scholar 

  • Meltzer HY (1980) Relevance of dopamine autoreceptors for psychiatry: preclinical and clinical studies. Schizophr Bull 6:456–475

    PubMed  CAS  Google Scholar 

  • Mignot E and Garcia A (1986) Sérotonine et dépression. Neuropsy 12:353–362

    Google Scholar 

  • Nieoullon A (1982) La transmission chimique de l’influx nerveux. Encycl Med Chir. Paris, Neurologie 17003, A10

    Google Scholar 

  • Oades RD (1987) Attention deficit disorder with hyperactivity: the contribution of catecholaminergic activity. Progress in Neurobiology 29:365–391

    Article  PubMed  CAS  Google Scholar 

  • Oliveras JL, Hosobuchi Y, Guilbaud G, Besson JR (1978) Analgesic electrical stimulation of the feline nucleus raphe magnus. Development of tolerance and its reversal by 5-HTP. Brain Research 146:404–409

    Article  PubMed  CAS  Google Scholar 

  • Patay M, Scharbach H and Levron M (1980) Glycine, acétylcholine et Sérotonine: neuro-transmédiateurs ou neuromodulateurs? Psycho Med 12:25–34

    Google Scholar 

  • Petitjean F, Buda C, Janin M, Sakai K, Jouvet M (1978) Patterns of sleep alteration following selective raphe nuclei lesions. Sleep Research 7:40

    Google Scholar 

  • Reynolds DV (1969) Surgery in the rat during electrical analgesia induced by focal brain stimulation. Science 104:444–445

    Article  Google Scholar 

  • Riddle MA, Leckman JF, Anderson GM, Ort SI, Hardin MT, Stevenson J, Cohen DJ (1988) Tourette’s syndrome: clinical and neurochemical correlates. J Am Acad Child Psychiatry 27:409–412

    Article  CAS  Google Scholar 

  • Riederer P, Toifl K and Kruzik P (1982) Excretion of biogenic amine metabolites in anorexia nervosa. Clin Chim Acta 123:27–32

    Article  PubMed  CAS  Google Scholar 

  • Roth RH (1979) Tyrosine hydroxylase. In: Horn AS, Korf J, Westerink BHC (eds) The neurobiology of dopamine. Academic, New York, pp 101–122

    Google Scholar 

  • Rothenberger A, Müller HU, Müller W (1990) Central versus peripheral disturbances in noradrenergic metabolism of adolescents with anorexia nervosa. In: Remschmidt H, Schmidt MH (eds). Child and Youth Psychiatry-European Perspectives, vol. 1, Huber, Houston Toronto Berlin, in press

    Google Scholar 

  • Rydin E, Schalling D, Asberg M (1982) Rorschach ratings in depressed and suicidal patients with low levels of 5-HIAA in CSF. Psychiatr Res 7:229–243

    Article  CAS  Google Scholar 

  • Sarnat HB (1987) Troubles de la migration neuronale terminale au cours de la période prénatale. Am J Dis Child 6, 59:380–390

    Google Scholar 

  • Schildkraut JJ, Keeler BA, Grab LL (1973) MHPG excretion and clinical classification in depressive disorders. Lancet 1:1251–1252

    Article  PubMed  CAS  Google Scholar 

  • Shaywitz BA, Cohen DJ and Bowers MB (1977) CSF monoamine metabolites in children with minimal brain dysfunction: evidence for alteration of brain dopamine. Pediatrics 90:67–71

    Article  CAS  Google Scholar 

  • Synder SH (1976) Catecholamines, serotonin and histamine. In: Siegel GJ, Alberts RW, Katzman R, Agranoff BW (eds) Basic neurochemistry. Little Brown, Boston, pp 203–217

    Google Scholar 

  • Soubrie P (1986) Neurones sérotoninergiques et comportement. J Pharmacol 11–2:107–112

    Google Scholar 

  • Stanley N, Vingilio J, Gershon S (1982) triated imipramine binding sites are decreased in the frontal cortox of suicide. Science 216:1337–1338

    Article  PubMed  CAS  Google Scholar 

  • Soubrie P (1986) Neurones sérotoninergiques et comportement. J Pharmacol 11–2:107–112

    Google Scholar 

  • Stoff DM, Pollock L, Bridger WH (1985) Platelet imipramine binding sites correlate with aggression in adolescents. In: Shagass C, Josiassen RC, Bridger WH, Weiss KJ, Stoff DM, Simpson G (eds) Biological psychiatry. Elsevier, New York, pp 180–183

    Google Scholar 

  • Tassin JP, Les Systèmes noradrénergiques centraux. Séminaire de psychiatrie biologique, Hôpital Ste Anne 1:81–96

    Google Scholar 

  • Willner P (1985) Antidepressants and serotoninergic neurotransmission: an integrative review. Psychopharmacology 85:307–404

    Article  Google Scholar 

  • Young JG, Cohen DJ, Anderson GM and Shaywitz BA (1984) Neurotransmitter. In: Greenhill L and Shopsin B (eds). Ontogeny and perspective for studies of child development and pathology of childhood. Spectrum, New York, pp 51–83

    Google Scholar 

  • Zemishlamy Z, Modai I, Apter A, jerushalmy Z, Samuel E and Tyano S (1987) Serotonin (5-HT) uptake by blood platelets in anorexia nervosa. Acta Psychiatr Scand 75:127–130

    Article  Google Scholar 

  • Zametkin AJ, Rapoport JL (1987) Neurobiology of attention deficit disorder with hyperactivity: where have we come in 50 years? J Amer Acad Child Adol Psychiatry 26:676–686

    Article  CAS  Google Scholar 

Download references

Authors
  1. B. Garreau
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. D. Lerminiaux
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. C. Barthélémy
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. J. P. Muh
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. G. Lelord
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. Kinder- und Jugendpsychiatrische Klinik am Zentralinstitut für Seelische Gesundheit, J5, D-6800, Mannheim 1, Germany

    Aribert Rothenberger

Rights and permissions

Reprints and permissions

Copyright information

© 1990 Springer-Verlag Berlin Heidelberg

About this paper

Cite this paper

Garreau, B., Lerminiaux, D., Barthélémy, C., Muh, J.P., Lelord, G. (1990). Monoaminergic Systems and Child Psychiatric Pathophysiology. In: Rothenberger, A. (eds) Brain and Behavior in Child Psychiatry. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-75342-8_4

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-75342-8_4

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-75344-2

  • Online ISBN: 978-3-642-75342-8

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics

Search

Navigation