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Schilddrüse

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Klinische Endokrinologie und Stoffwechsel

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Zusammenfassung

Die Schilddrüse entwickelt sich aus einer Ausstülpung des Entoderms in der Mitte der Mundbucht in der 3. Woche nach der Konzeption. Nach einer zweilappigen Auf teilung wandert die Schilddrüse vom Ausgangspunkt, dem Foramen coecum, kaudalwärts. Der Ductus thyreoglossus, die Verbindung zwischen Foramen coecum und endgültiger Lage der Schilddrüse etwa in Höhe des 2.-4. Trachealringes, obliteriert postpartal. Nicht selten bildet der kaudale Anteil des Ductus thyreoglossus den Lobus pyramidalis. Beide Schilddrüsenlappen bleiben durch den prä tracheal gelegenen Isthmus verbunden. Die Schilddrüse setzt sich aus zahllosen Follikeln zusammen, die aus einzelnen, aneinander gereihten Zellen bestehen, die einen mit Kolloid gefüllten Hohlraum umgeben. Im Kolloid werden Schilddrüsenhormone im Thyreoglobulinmolekül gespeichert und synthetisiert.

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  1. J. Feldkamp
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  2. W. A. Scherbaum
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  1. Medizinische Klinik IV, Universitätsklinikum Tübingen, Otfried-Müller-Straße 10, 72076, Tübingen, Deutschland

    Peter P. Nawroth

  2. Abteilung Innere Medizin I, Medizinische Universitätsklinik und Poliklinik Heidelberg, Bergheimer Straße 58, 69115, Heidelberg, Deutschland

    Reinhard Ziegler

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Feldkamp, J., Scherbaum, W.A. (2001). Schilddrüse. In: Nawroth, P.P., Ziegler, R. (eds) Klinische Endokrinologie und Stoffwechsel. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-56784-1_4

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