Skip to main content

Kutanes Melanom

  • Chapter
Plastische Chirurgie
  • 226 Accesses

Zusammenfassung

Als Melanom wird ein maligner Tumor bezeichnet, der von der malignen Entartung der Melanozyten ausgeht. Diese dendritenähnlichen Pigmentzellen befinden sich hauptsächlich in der Basalzellreihe der Epidermis oder sind in allen histologischen Typen der Pigmentnävi angehäuft. Zwei Drittel der Melanome gehen direkt aus der Epidermis und ein Drittel aus bereits existierenden Pigmentnävi hervor. Darüber hinaus befinden sich Melanozyten auch an Schleimhäuten, Retina und weniger an den Leptomeningen, im inneren Ohr und in der Uvea des Auges. Folglich entwickeln sich 90 % der Melanome primär an der Haut (kutanes Melanom) und 10 % vorwiegend an den Schleimhäuten und im Auge [22].

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 179.00
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 229.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 229.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

Literatur

  1. Ames FC, Balch CM, Reintgen D (1992) Local recurrences and there management. In: Balch CM et al. (eds) Cutaneous melanoma, 2nd edn. Lippincott, Philadelphia

    Google Scholar 

  2. Anderson C, Buzaid A, Legha S (1995) Systemic treatment for advanced cutaneous melanoma. Oncology 9:1149

    PubMed  CAS  Google Scholar 

  3. Argenziano G, Soyer HP, De Giorgi V, Piccolo D et al. (2000) Dermatoscopy. A Tutorial. EDRA Medical Publishing and New Media, Mailand

    Google Scholar 

  4. Ariyan S (1996) General principles of reconstruction following cancer surgery. Surg Oncol Clin North Am 5: 741

    CAS  Google Scholar 

  5. Autier P (1994) Epidemiology of melanoma. In: Lejeuine FJ, Chaudhuri PK, DasGupta TK (eds) Malignant melanoma: medical and surgical management. McGraw-Hill, New York, ch.1

    Google Scholar 

  6. Balch C, Buzaid A (1996) Finally an effective adjuvant therapy for melanoma (editorial) J Clin Oncol 14:1

    PubMed  CAS  Google Scholar 

  7. Balch CM, Soong S, Murad TM et al. (1981) A multifactorial analysis of melanoma. III. Prognostic factors in melanoma patients with lymph node métastases (stage II). AnnSurg 193: 377

    CAS  Google Scholar 

  8. Balch CM, Urist MM, Karakousis CP et al. (1993) Efficacy of 2-cm surgical margins for intermediate thickness melanomas (1 to 4 mm). Ann Surg 218: 262

    Article  PubMed  CAS  Google Scholar 

  9. Balch CM, Soong SJ, Bartolucci A et al. (1996) Efficacy of an elective node dissection of 1 to 4 mm thick melanomas for patients 60 years of age and younger. Ann Surg 224: 255

    Article  PubMed  CAS  Google Scholar 

  10. Balch CM, Ross M, Soong SJ, Harison M (2000) Long-term results of a prospective, randomized trial involving elective regional lymph node dissection in patients with intermediate thickness melanoma. Ann Surg 7: 87

    Article  CAS  Google Scholar 

  11. Balch CM et al. (2000) A new American Joint Committee on Cancer Staging System for cutaneous melanoma. Cancer 88:1485

    Article  Google Scholar 

  12. Bedrosian I, Faries MB et al. (2000) Incidence of sentinel node metastasis in patients with thin primary melanoma with vertical growth phase. Ann Surg Oncol 7/4: 262

    Article  Google Scholar 

  13. Binder M, Schwarz M, Winkler A, Steiner A, Kaider A, Wolff K, Pehamberger H (1995) Epiluminescence microscopy. A useful tool for the diagnosis of pigmented skin lesions for formallz trained dermatologists. Arch Dermatol 131: 286–291

    Article  PubMed  CAS  Google Scholar 

  14. Blaheta HJ, Schittek B, Sotlar K,Ellwanger U, Garbe C (1998) Molekularbiologischer Nachweis einer Mikrometasta-sierung an Lymphknotengewebe von Melanompatienten mittels Tyrosinase RT-PCR. In: Garbe C, Rassner G (eds) Dermatologie — Leitlinien und Qualitätssicherung für Diagnostik und Therapie. Springer, Berlin Heidelberg New York Tokyo

    Google Scholar 

  15. Breslow A (1970) Thickness, cross-sectional areas and depth of invasion in the prognosis of cutaneous melanoma. Ann Surg 172: 902–908

    Article  PubMed  CAS  Google Scholar 

  16. Buzaid AC, Ross MI, Balch CM, Soong S, McCarthy CH, Tinoco I (1997) Critical analysis of the current American Committee on Cancer staging system for cutaneous melanoma and proposal of a new staging system. J Clin Oncol 15:1039

    PubMed  CAS  Google Scholar 

  17. Buzzel RA, Zitelli JA (1996) Favorable prognostic factors in recurrent and metastatic melanoma. J Am Acad Dermatol 34: 798

    Article  Google Scholar 

  18. Cascinelli N, van der Esch EP, Breslow A, Morabito A, Bufalino R (1980) Stage I melanoma of the skin. The problem with resection margins. Eur J Cancer 16:1079

    Article  Google Scholar 

  19. Cascinelli N, Santinami M, Urist MM, Holmstrom H (1987) Indications for management. In: Veronesi U et al. (eds) Cutaneous melanoma. Academic Press, London, pp 545–553

    Google Scholar 

  20. Cascinelli N, Bufalino R et al. (1994) Results of adjuvant interferon study in WHO programme. Lancet 343: 913

    Article  PubMed  CAS  Google Scholar 

  21. Cascinelli N, Morabito A, Sentinami M, MacKie RM, Belli F (1998) Immediate or delayed dissection of regional nodes in Patients with melanoma of the trunck: a randomized trial WHO Melanoma Programme. Lancet 351: 793

    Article  PubMed  CAS  Google Scholar 

  22. Chang AE, Karnell LH, Menck HR (1998) The National Cancer Data Report on Cutaneous and Non-Cutaneous Melanoma. Cancer 83:1664–1678

    Article  PubMed  CAS  Google Scholar 

  23. Clark WH (1967) A classification of malignant melanoma in man correlated with histogenesis and biologic behavior. In: Montagna W, Hu F (eds) Advances in biology of the skin. The pigmentary System. Vol 8. Pergamon, London, pp 621–645

    Google Scholar 

  24. Cochran AJ (1971) Studies of the melanocytes of the epidermis adjacent to tumors. J Invest Dermatol 57:38

    Article  PubMed  CAS  Google Scholar 

  25. Cochran AJ (2001) Value of molecular diagnostic techniques in assessment of sentinel nodes. 5th World Congress on Melanoma, Venedig. Melanoma Res 11(Suppl 1): 11

    Google Scholar 

  26. Coit DG (1993) Role of surgery for metastatic malignant melanoma: A review. Semin Surg Oncol 9: 239

    PubMed  CAS  Google Scholar 

  27. Creech O Krementz ET, Ryan RF et al. (1958) Chemotherapy of cancer: Regional perfusion utilizing an extracorporeal circuit. Ann Surg 148: 616

    Article  PubMed  Google Scholar 

  28. Diffey BL (1995) Ultraviolet irradiation and the skin. Proceedings of the Melanoma’ 95 Meeting in Brighton. Melanoma Res 5(Suppl 1): 13

    Article  Google Scholar 

  29. Elder DE et al. (1981) Acquired melanocytic nevi and melanoma: the dysplastic nevus syndrome. In: Ackerman AB (ed) Pathology of malignant melanoma. Masson, New York

    Google Scholar 

  30. Elder DE, Guerry DIV, Heiberger RM, La Rossa D, Van Horn M (1983) Optimal resection margin for cutaneous malignant melanoma. Plast Reconstr Surg 71: 66

    PubMed  CAS  Google Scholar 

  31. Elwood JM, Gallagher RP, Davison J, Hill GB (1985) Cutaneous melanoma in relation to intermittent and constant sun exposure. Cancer 35: 427–433

    CAS  Google Scholar 

  32. Flotte TJ, Tannous ZS, Mihm Me (2001) Lentigo maligna and tumor progression. Proceedings of the 5th World Conference on Melanoma. Melanoma Res 11(Suppl 1): 36

    Google Scholar 

  33. Fraker DL (1998) Hyperthermic regional perfusion for melanoma of the limbs. In: Balch CM et al. (eds) Cutaneous melanoma, 2nd edn. Lippincott, Philadelphia

    Google Scholar 

  34. French Cooperative Group (1998) In: Balch et al. (eds) Cutaneous melanoma, 3rd edn. QM, Missouri, pp 142–144

    Google Scholar 

  35. Friedman GJ, Rigel DS (1985) The clinical features of malignant melanoma. Dermatol Clin 3: 271–283

    PubMed  CAS  Google Scholar 

  36. Garbe C (1992) Sonne und malignes Melanom. Hautarzt 43: 251–257

    PubMed  CAS  Google Scholar 

  37. Garbe C, Orfanos CE (1989) Epidemiologie des malignen Melanoms in der Bundesrepublik Deutschland im internationalen Vergleich. Onkologie 12: 253–262

    Article  PubMed  CAS  Google Scholar 

  38. Garbe C, Schaumburg-Lever G (1997) Klinik und Histologie des malignen Melanoms. In: Garbe C et al. (eds) Dermatologische Onkologie. Springer, Berlin Heidelberg New York Tokyo

    Chapter  Google Scholar 

  39. Garbe C, Büttner P, Weiss J et al. (1994) Associated factors in the prevalence of more than 50 common melanocytic nevi, atypical melanocytic nevi and actinic lentigines. Multicenter case-control study of the Central Malignant Melanoma Registry of the German Dermatological Society. J Invest Dermatol 102: 700–705

    Article  PubMed  CAS  Google Scholar 

  40. Garbe C, Büttner P, Weiss J et al. (1994) Risk factors for developing cutaneous melanoma and criteria for identifying persons at risk: Multicenter case-control study of the Central Malignant Melanoma Registry of the German Dermatological Society. J Invest Dermatol 102: 695–699

    Article  PubMed  CAS  Google Scholar 

  41. Garbe C, Büttner P et al. (1995) Malignes Melanom der Deutschen Dermatologischen Gesellschaft in den Jahren 1983–1993. Epidemiologische Entwicklungen und aktuelle therapeutische Versorgung des malignen Melanoms der Haut. Hautarzt 46: 683–692

    Article  PubMed  CAS  Google Scholar 

  42. Gershenwald JE, Mansfield PF, Lee JE, Ross MI (2000) Role for lymphatic mapping and sentinel lymph node biopsy in patients with thick primary melanoma. Ann Surg Oncol 7/4:160

    Article  Google Scholar 

  43. Grob JJ, Dreno B et al. (1998) Randomised trial of interferon a-2a as adjuvant therapz in resected primary melanoma thicker than 1,5 mm without clinically detectable métastase. Lancet 351:1905

    Article  PubMed  CAS  Google Scholar 

  44. Hill S, Meirion Thomas J (1996) Using CO2to manage cutaneous metastases from malignant melanoma. Br J Surg 83: 509

    Article  PubMed  CAS  Google Scholar 

  45. Hoffmann K, Jung J, Gammal S, Altmayer P (1992) Malignant melanoma in 20-MHz scan sonography. Dermatology 185: 49–55

    Article  PubMed  CAS  Google Scholar 

  46. Jonk A, Kroon BBR et al. (1988) Results of radical dissection of the groin in patients with stage II melanoma and histo-logically proved metastasses of the iliac or obturator lymph nodes or both. Surg Gyn Obstet 167: 28

    CAS  Google Scholar 

  47. Karakousis CP, Balch CM, Urist M et al. (1996) Local recurrence in malignant melanoma: Long term results of the multi-institutional randomized surgical trial. Ann Surg Oncol 3: 446

    Article  PubMed  CAS  Google Scholar 

  48. Kelly JW, Sagebiel RW, Calderon W et al. (1984) The frequency of local recurrence and microsatellites as a guide to reexcision margins for cutaneous malignant melanoma. Ann Surg 20: 759

    Google Scholar 

  49. Kenady DE, Brown BW, McBride CM (1982) Excision of underlying fascia with a primary malignant melanoma: Effect on recurrence and survival rates. Surgery 92: 615

    PubMed  CAS  Google Scholar 

  50. Kirkwood JM, Strawderman MH, Ernstoff MS et al. (1996) Interferon alfaß2b adjuvant therapy of high risk resected cutaneous melanoma. The Eastern Cooperative Oncology Group Trial EST 1684. J Clin Oncol 14: 7

    PubMed  CAS  Google Scholar 

  51. Kirkwood JM, Ibrahim JG, Sasman JA et al. (2001) Highdose Interferon alfa-2b significantly prolongs relaps-free and overall survival compared with the GM2-KLH/QS-21 Vaccine in Patients with resected stage IIB-III melanoma: Results of intergroup trial E 1694/S9512/C509801. J Clin Oncol 19: 2370

    PubMed  CAS  Google Scholar 

  52. Klein-Szanto AJP, Silvers WK, Mintz B (1994) Ultraviolet radiation-induced malignant skin melanoma in melanoma-susceptible transgenic mice. Pigment Cell Res 54: 4569

    CAS  Google Scholar 

  53. Koopal SA, Tieboesch ATM, Piers DA et al. (2000) Frozen section analysis of sentinel lymph nodes in melanoma patients. Cancer 89:1720

    Article  PubMed  CAS  Google Scholar 

  54. Lejeune FJ (2001) The future of isolated limb perfusion in melanoma. 5th World Congress on Melanoma, Venedig. Melanoma Res 11(Suppl 1): 46

    Google Scholar 

  55. Lienard D, Eggermont AM et al. (1994) Isolated perfusion of the limb with high dose TNF-α, IFN-α and melphalan for melanoma stage III. Results of a multicenter pilot study. Med Res 4(Suppl 1): 21

    Google Scholar 

  56. Matey P, Marsden JR, Sanders DSA (1997) Lentigo maligna: results of biopsy and 2 mm margin excision. Abstr 39, 4th World Congress on Melanoma, Sydney

    Google Scholar 

  57. McHenry PM (1995) Treatment of lentigo maligna. Proceedings of the Melanoma’ 95 Meeting in Brighton. Melanoma Res 5(Suppl 1): 19

    Article  Google Scholar 

  58. Meyers ML, Balch CM (1998) Diagnosis and treatment of metastatic melanoma. In: Balch CM et al. (eds) Cutaneous melanoma, 2nd edn. Lippincott, Philadelphia

    Google Scholar 

  59. Middleton MR et al. (1999) A randomised phase III study of temozolamide (TMZ) versus decarbasine (DTIC) in the treatment of patients with advanced metastatic melanoma. Proc ASCO, Abstr 2069

    Google Scholar 

  60. Morton DL, Wen DR, Wong JH et al. (1992) Technical details of intraoperative lymphatic mapping for early stage melanoma. Arch Surg 127:392

    Article  PubMed  CAS  Google Scholar 

  61. Nakashira I, Kato M, Takeda Y, Kawamoto A, Akhand A, Suzuki T, Dragani A (2001) Melanoma development in RET-transgenic mice. Proceedings of the 5th World Conference on Melanoma. Melanoma Res 11(Suppl 1): 17

    Google Scholar 

  62. Orfanos CE, Jung EG, Rassner G et al. (1994) Stellungsnahme und Empfehlung der Kommission malignes Melanom der Deutschen Dermatologischen Gesellschaft zur Diagnostik, Behandlung und Nachsorge des malignen Melanoms der Haut. Stand 1993/1994. Hautarzt 45: 285

    Article  PubMed  CAS  Google Scholar 

  63. Orton JP (1994) Biology and photobiology of the melanin pigmentary system. In: Lejeune FJ et al. (eds) Malignant melanoma: medical and surgical management. McGraw-Hill, New York, ch. 7

    Google Scholar 

  64. Pehamberger H, Steiner A, Wolff K (1987) In vivo epilu-minescence microscopy of pigmented skin lesions. I. Pattern analysis of pigmented skin lesions. J Am Acad Der-matol 17: 571–583

    Article  CAS  Google Scholar 

  65. Pehamberger H, Soyer P et al. (1998) Adjuvant interferon alfa-2a treatment in resected primary Stage II cutaneous melanoma. J Clin Oncol 16:1425

    PubMed  CAS  Google Scholar 

  66. Porter GA, Ross MI, Berman RS et al. (2000) Significance of multiple nodal basin drainage in truncal melanoma patients undergoing sentinel lymph node biopsy. Ann Surg Oncol 7/4: 256

    Article  Google Scholar 

  67. Provost N, Kopf AW, Rabinovitz HS, Stolz W, De David M, Wasti Q, Bart RS (1998) Comparison of conventional photographs and telephonically transmitted digitized images of melanomas and dysplastic nevi. Dermatology 196: 299–304

    Article  PubMed  CAS  Google Scholar 

  68. Rapaport DP, Stadelmann WK, Reintgen DS (1998) Inguinal lymphadenectomy. In: Balch CM et al. (eds) Cutaneous melanoma, 3rd edn. QM, Missouri

    Google Scholar 

  69. Reintgen D, Cruse CW, Wells K, Berman C et al. (1994) The ordery progression of melanoma nodal metastases. Ann Surg 220: 759

    Article  PubMed  CAS  Google Scholar 

  70. Retsas S, Quigley M, Pectasidis D et al. (1994) Clinical and histologic involvement of regional lymph nodes in malignant melanoma. Adjuvant Vindesin improves survival. Cancer 73: 2119

    Article  PubMed  CAS  Google Scholar 

  71. Rhodes AR (1994) Potential precursors of cutaneous melanoma. In: Lejeune FJ et al. (eds) Malignant melanoma: medical and surgical management. McGraw-Hill, New York, pp 98 ff

    Google Scholar 

  72. Rhodes AR, Harrist TJ, Day CL, Mihm MC, Fitzpatrick TB, Sober AJ (1983) Dysplastic melanocytic nevi in histological association with 234 primary cutaneous melanoma. J Am Acad Dermatol 9: 563–574

    Article  PubMed  CAS  Google Scholar 

  73. Rigel DS (1997) Precursor lesions and melanoma. Proceedings of the 4th World Conference on Melanoma. Melanoma Res 7(Suppl 1): S2

    Article  Google Scholar 

  74. Rigel DS (1997) Malignant melanoma: Incidence issues and their effect on diagnosis and treatment in the 1990s. Mayo Clin Proc 72/4:367–371

    Article  Google Scholar 

  75. Robinson JK (1994) Margin control for Lentigo maligna. J Am Acad Dermatol 31: 79

    Article  PubMed  CAS  Google Scholar 

  76. Robinson ES, Vande Berg JL, Hubbard GB, Dooley TP (1994) Malignant melanoma in ultraviolet irradiated laboratory opossums. Initiation in suckling young, metastasis in adult and xenograph behavior in nude mice. Cancer Res 54:5986

    PubMed  CAS  Google Scholar 

  77. Runger TM, Epe B, Moller K (1995) Processing of directly and indirectly ultraviolet-induced DNA damage in human cells. Recent Results Cancer Res 139: 31

    Article  PubMed  CAS  Google Scholar 

  78. Sack H (1996) Strahlentherapie des Melanoms. Onkologe 2: 473

    Article  Google Scholar 

  79. Sancho-Garnier H, Harrison S, Daures JP (1997) Melanocytic naevi in children aged 3 to 6 years in France and Australia. Proceedings of the 4th World Conference on Melanoma. Melanoma Res 7(Suppl 1): S5

    Article  Google Scholar 

  80. Saxman SB et al. (1999) A phase III multicenter randomized trial of DTIC alone in Patients with metastatic melanoma. Proc ASCO, Abstr 2068

    Google Scholar 

  81. Schulte KW, Rief P, Franke W, Ruzicka T (2001) Malignant Melanoma: epidemiological data from Düsseldorf area. Schweiz Rundsch Med Prax: 90: 293–296

    CAS  Google Scholar 

  82. Seegenschmiedt MH, Keilholz L, Altendorf-Hopfmann A et al. (1999) Langzeitergebnisse nach Strahlentherapie beim lokal rezidivierten und metastasierten malignen Melanom. Hautarzt 50: 572

    Article  PubMed  CAS  Google Scholar 

  83. Setlow RB, Woodhead AD, Grist E (1989) Animal model for ultraviolet radiation-induced melanoma. Platy fish-sward tail hybrid. Proc Natl Acad Sci USA 86: 8922

    Article  PubMed  CAS  Google Scholar 

  84. Setlow RB, Grist E, Thompson K, Woodhead AD (1992) Wavelengths effective in induction of malignant melanoma. Proc Natl Acad Sci 86: 8922

    Article  Google Scholar 

  85. Shen P, Guenther JM, Wanek LA, Morton DL (2000) Can elective lymph node dissection decrease the frequency and mortality rate of late melanoma recurrence? Ann Surg Oncol 2:114

    Article  Google Scholar 

  86. Shivers SC, Wang X et al. (1996) Molecular staging of malignant melanoma. JAMA 280:1410

    Article  Google Scholar 

  87. Stadler R, Garbe C (1991) Nävus-assoziierte maligne Mela-nome-diagnostische Sicherung und Prognose. Hautarzt 42: 424–429

    PubMed  CAS  Google Scholar 

  88. Tilgen W, Uhl K (1998) Palliative Therapie des malignen Melanoms. In: Garbe C, Rassner G (eds) Dermatologie — Leitlinien und Qualitätssicherung für Diagnostik und Therapie. Springer, Berlin Heidelberg New York Tokyo, pp288

    Google Scholar 

  89. Urist MM, Balch C, Milton GW (1985) Surgical management of the primary melanoma. In: Balch CM, Milton GW (eds) Cutaneous melanoma. Lippincott, Philadelphia, pp 71–90

    Google Scholar 

  90. Veronesi U, Cascinelli N (1991) Narrow excision margin; a safe procedure for thin cutaneous melanoma. Arch Surg 126: 438

    Article  PubMed  CAS  Google Scholar 

  91. Waldmann V, Bock M, Jäckel A, Deichmann M, Docken-dorff K: Pathogenese des malignen Melanoms. Hautarzt 50: 398–405

    Google Scholar 

  92. Weinstock MA, Sober AJ (1987) The risk of progression of Lentigo maligna to Lentigo maligna melanoma. Br J Der-matol 116: 303

    CAS  Google Scholar 

  93. Weiss J, Herbst RA, Kapp A (2000) Malignant melanoma of the skin. Pathogenesis, clinical aspects and prognosis. Versicherungsmedizin 52/1: 7–12

    Google Scholar 

  94. Weiss M, Konz B, Schmied-Wendtner MH et al. (2000) Métastases in malignant melanoma despite histologically negative sentinel lymph node: should the concept be changed? Nuklearmedizin 39: 214

    PubMed  CAS  Google Scholar 

  95. Wolf P, Donawho C, Fidler IJ, Kripke ML (1994) Effects of sunscreens on UV radiation induced enhancement of melanoma growth in mice. Proc Natl Acad Sci 86: 99

    CAS  Google Scholar 

  96. Wolff IH, Smolle J, Soyer HP, Kerl H (1998) Sensitivity in the clinical diagnosis of malignant melanoma. Melanoma Res 8: 425–429

    Article  Google Scholar 

  97. Wong CK (1970) A study of melanocytes in the normal skin surrounding malignant melanomas. Dermatologica 141: 215

    Article  PubMed  CAS  Google Scholar 

  98. Wong JH, Cagle LA, Morton DL (1987) Surgical treatment of lymph nodes with metastatic melanoma from unknown primary site. Arch Surg 122:1380

    Article  PubMed  CAS  Google Scholar 

  99. Wong JH, Cagle LA, Morton D (1991) Lymphatic drainage of skin to a sentinel lymph node in a feline model. Ann Surg 214: 637

    Article  PubMed  CAS  Google Scholar 

  100. Yamamoto A (1997) The epidemiology of melanoma in the East. Proceedings of the 4th World Conference on Melanoma. Melanoma Res 7(Suppl 1): S2

    Google Scholar 

Download references

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2003 Springer-Verlag Berlin Heidelberg

About this chapter

Cite this chapter

Ioannovich, I.D. (2003). Kutanes Melanom. In: Berger, A., Hierner, R. (eds) Plastische Chirurgie. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-55886-3_16

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-55886-3_16

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-62713-2

  • Online ISBN: 978-3-642-55886-3

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics