Zusammenfassung
Die Ernährungsunterstützung des Brandverletzten ist ein wichtiger Teil der Behandlung. Diese Unterstützung sollte möglichst rasch und physiologisch durchgeführt werden. Das heißt, eine enterale Ernährung sollte bevorzugt durchgeführt werden. Studien zeigen eine Reduktion von Mortalität und Morbidität bei enteraler Ernährung. Die Ermittlung des Energiebedarfs kann durch eine Kalorimetrie oder daran angelehnte Formeln erfolgen. Bei Kindern sollte die Schofield-, bei Erwachsenen die Toronto-Formel herangezogen werden. Entscheidend ist nicht nur die Quantität, sondern auch die Qualität der Ernährung. So sollte die Hauptenergiequelle aus Proteinen und Kohlenhydraten bestehen. Der übermäßige Einsatz von Lipiden erhöht die Mortalität. Neben den genannten Hauptenergiequellen müssen auch Vitamine und Spurenelemente in ausreichender Menge zugeführt werden. Medikamentöse Therapeutika in Form von Wachstumsfaktoren, Hormonen und Betablockern stehen zur Reduktion des kritischen Katabolismus zur Verfügung und reduzieren zeitgleich die Mortalität und Morbidität.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Literatur
ASPEN (2009) Clinical Guidelines for the Use of Parenteral and Enteral Nutrition in Adult and Pediatric Patients. J Parenter Enter Nutr 33:255–259
Baron PW, Barrow RE, Pierre EJ, Herndon DN (1997) Prolonged use of propranolol safely decreases cardiac work in burned children. J Burn Care Rehabil 18:223–227
Barret JP, Jeschke MG, Herndon DN (2001) Fatty infiltration of the liver in severely burned pediatric patients: autopsy findings and clinical implications. J Trauma 51:736–739
Bell SJ, Molnar JA, Krasker WS, Burke JF (1986) Weight maintenance in pediatric burned patients. J Am Diet Assoc 86:207–211
Biesalski HK, McGregor GP (2007) Antioxidant therapy in critical care – is the microcirculation the primary target? Crit Care Med 35:S577–S583
Branski LK, Herndon DN, Barrow RE, Kulp GA, Klein GL et al (2009) Randomized controlled trial to determine the efficacy of long-term growth hormone treatment in severely burned children. Ann Surg 250:514–523
Demling RH, Orgill DP (2000) The anticatabolic and wound healing effects of the testosterone analog oxandrolone after severe burn injury. J Crit Care 15:12–17
Demling RH, Seigne P (2000) Metabolic management of patients with severe burns. World J Surg 24:673–680
Gamliel Z, DeBiasse MA, Demling RH (1996) Essential microminerals and their response to burn injury. J Burn Care Rehabil 17:264–272
Garrel D (2003) The effect of supplemental enteral glutamine on plasma levels, gut function, and outcome in severe burns. JPEN J Parenter Enteral Nutr 28:123; author reply 123
Garrel DR, Razi M, Larivière F, Jobin N, Naman N et al (1995) Improved clinical status and length of care with low-fat nutrition support in burn patients. 482-491
Gore DC, Chinkes D, Heggers J, Herndon DN, Wolf SE et al (2001) Association of hyperglycemia with increased mortality after severe burn injury. J Trauma 51:540–544
Gore DC, Herndon DN, Wolfe RR (2005) Comparison of peripheral metabolic effects of insulin and metformin following severe burn injury. J Trauma 59:316–322; discussion 322–323
Guerra TL de S, Mendonça SS, Marshall NG (2013) Incidence of constipation in an intensive care unit. Rev Bras Ter Intensiva 25:87–92
Hart DW, Herndon DN, Klein G, Lee SB, Celis M et al (2001) Attenuation of posttraumatic muscle catabolism and osteopenia by long-term growth hormone therapy. 827-834
Hart DW, Wolf SE, Mlcak R, Chinkes DL, Ramzy PI et al (2000) Persistence of muscle catabolism after severe burn. Surgery 128:312–319
Hart DW, Wolf SE, Ramzy PI, Chinkes DL, Beauford RB et al (2001) Anabolic effects of oxandrolone after severe burn. Ann Surg 233:556–564
Hemmila MR, Taddonio MA, Arbabi S, Maggio PM, Wahl WL (2008) Intensive insulin therapy is associated with reduced infectious complications in burn patients. Surgery 144:629–637
Herndon DN, Barrow RE, Stein M, Linares H, Rutan TC et al (1989) Increased mortality with intravenous supplemental feeding in severely burned patients. 309-313
Herndon DN, Hart DW, Wolf SE, Chinkes DL, Wolfe RR (2001) Reversal of catabolism by beta-blockade after severe burns. 1223-1229
Herndon DN, Ramzy PI, DebRoy MA, Zheng M, Ferrando AA et al (1999) Muscle protein catabolism after severe burn: effects of IGF-1/IGFBP-3 treatment. 713-720; discussion 720-722
Hunt DR, Lane HW, Beesinger D, Gallagher K, Halligan R et al (1984) Selenium depletion in burn patients. JPEN J Parenter Enteral Nutr 8:695–699
Ireton-Jones CS, Turner WW (1987) The use of respiratory quotient to determine the efficacy of nutrition support regimens. J Am Diet Assoc 87:180–183
Jeschke MG, Kulp GA, Kraft R, Finnerty CC, Mlcak R et al (2010) Intensive Insulin Therapy in Severely Burned Pediatric Patients. Am J Respir Crit Care Med 182:351–359
Klein GL, Wolf SE, Langman CB, Rosen CJ, Mohan S et al (1998) Effects of therapy with recombinant human growth hormone on insulin-like growth factor system components and serum levels of biochemical markers of bone formation in children after severe burn injury. 21–24
Kremer T, Harenberg P, Hernekamp F, Riedel K, Gebhardt MM et al (2010) High-dose vitamin C treatment reduces capillary leakage after burn plasma transfer in rats. J Burn Care Res 31:470–479
Kreymann KG, Berger MM, Deutz NEP, Hiesmayr M, Jolliet P et al (2006) ESPEN Guidelines on Enteral Nutrition: Intensive care. Clin Nutr 25:210–223
Kudsk KA, Stone JM, Sheldon GF (1982) Nutrition in trauma and burns. Surg Clin North Am 62:183–192
Long C (1979) Energy expenditure of major burns. J Trauma 19:904–906
Matsuda T, Kagan RJ, Hanumadass M, Jonasson O (1983) The importance of burn wound size in determining the optimal calorie:nitrogen ratio. Surgery 94:562–568
Mayes T, Gottschlich MM, Warden GD (1997) Clinical nutrition protocols for continuous quality improvements in the outcomes of patients with burns. J Burn Care Rehabil 18:365–368; discussion 364
Mochizuki H, Trocki O, Dominioni L, Alexander JW (1985) Reduction of postburn hypermetabolism by early enteral feeding. Curr Surg 42:121–125
Møller S, Jensen M, Svensson P, Skakkebaek NE (1991) Insulin-like growth factor 1 (IGF-1) in burn patients. Burns 17:279–281
Murphy KD, Thomas S, Mlcak RP, Chinkes DL, Klein GL et al (2004) Effects of long-term oxandrolone administration in severely burned children. Surgery 136:219–224
Pereira CT, Jeschke MG, Herndon DN (2007) Beta-blockade in burns. Novartis Found Symp 280:238–248; discussion 248–251
Pham TN, Cancio LC, Gibran NS (2008) American Burn Association practice guidelines burn shock resuscitation. J Burn Care Res 29:257–266
Pham TN, Warren AJ, Phan HH, Molitor F, Greenhalgh DG et al (2005) Impact of tight glycemic control in severely burned children. J Trauma 59:1148–1154
Rodriguez NA, Jeschke MG, Williams FN, Kamolz L-P, Herndon DN (2011) Nutrition in burns: Galveston contributions. JPEN J Parenter Enteral Nutr 35:704–714
Rousseau A-F, Losser M-R, Ichai C, Berger MM (2013) ESPEN endorsed recommendations: Nutritional therapy in major burns. Clin Nutr 32:497–502
Rutan RL, Herndon DN (1990) Growth delay in postburn pediatric patients. Arch Surg 125:392–395
Saffle JR, Medina E, Raymond J, Westenskow D, Kravitz M et al (1985) Use of indirect calorimetry in the nutritional management of burned patients. J Trauma 25:32–39
Schutz Y (1995) The basis of direct and indirect calorimetry and their potentials. Diabetes / Metab Rev 11:383–408
Selmanpakoglu AN, Cetin C, Sayal A, Isimer A (1994) Trace element (Al, Se, Zn, Cu) levels in serum, urine and tissues of burn patients. Burns 20:99–103
Spodaryk M, Kobylarz K (2005) The usability of harris-benedict and curreri equations in nutritional management of thermal injuries. Ann Burns Fire Disasters 18:117–121
Suman OE, Mlcak RP, Chinkes DL, Herndon DN (2006) Resting energy expenditure in severely burned children: analysis of agreement between indirect calorimetry and prediction equations using the Bland-Altman method. Burns 32:335–342
Takala J, Ruokonen E, Webster NR, Nielsen MS, Zandstra DF et al (1999) Increased mortality associated with growth hormone treatment in critically ill adults. 785-792
Waymack JP, Herndon DN (1992) Nutritional support of the burned patient. World J Surg 16:80–86
Williams FN, Jeschke MG, Chinkes DL, Suman OE, Branski LK et al (2009) Modulation of the Hypermetabolic Response to Trauma: Temperature, Nutrition, and Drugs. J Am Coll Surg 208:489–502
Williams FN, Branski LK, Jeschke MG, Herndon DN (2011) What, how, and how much should patients with burns be fed? Surg Clin North Am 91:609–629
Williams FN, Herndon DN, Kulp GA, Jeschke MG (2011) Propranolol decreases cardiac work in a dose-dependent manner in severely burned children. Surgery 149:231–239
Wilmore DW, Mason AD, Pruitt BA (1976) Insulin response to glucose in hypermetabolic burn patients. Ann Surg 183:314–320
Wischmeyer PE, Lynch J, Liedel J, Wolfson R, Riehm J et al (2001) Glutamine administration reduces Gram-negative bacteremia in severely burned patients: a prospective, randomized, double-blind trial versus isonitrogenous control. Crit Care Med 29:2075–2080
Wolf SE, Rose JK, Desai MH, Mileski JP, Barrow RE et al (1997) Mortality determinants in massive pediatric burns. An analysis of 103 children with > or = 80% TBSA burns (> or = 70% full-thickness). Ann Surg 225:554–565; discussion 565–569
Wolfe RR, Goodenough RD, Burke JF, Wolfe MH (1983) Response of protein and urea kinetics in burn patients to different levels of protein intake. Ann Surg 197:163–171
Zhou Y-P, Jiang Z-M, Sun Y-H, Wang X-R, Ma E-L et al (2003) The effect of supplemental enteral glutamine on plasma levels, gut function, and outcome in severe burns: a randomized, double-blind, controlled clinical trial. JPEN J Parenter Enteral Nutr 27:241–245
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2016 Springer-Verlag Berlin Heidelberg
About this chapter
Cite this chapter
Wallner, C., Behr, B., Lehnhardt, M. (2016). Ernährung. In: Lehnhardt, M., Hartmann, B., Reichert, B. (eds) Verbrennungschirurgie. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-54444-6_15
Download citation
DOI: https://doi.org/10.1007/978-3-642-54444-6_15
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-642-54443-9
Online ISBN: 978-3-642-54444-6
eBook Packages: Medicine (German Language)