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Kreislaufphysiologische Grundlagen

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Transfusionsmedizin und Immunhämatologie

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Zusammenfassung

Das Blutvolumen bezeichnet die Gesamtmenge des zirkulierenden Blutes und unterliegt normalerweise nur geringen Schwankungen. Es wird durch verschiedenste Regulationsmechanismen beeinflusst. Als Grundlage dient hier die optimale Anpassung des Volumens und der Zusammensetzung des Blutes an die speziellen Erfordernisse des Kreislaufes. Die Hauptaufgaben des Blutes sind die Versorgung des Gewebes mit Sauerstoff und Nährstoffen, der Abtransport von Stoffwechselprodukten und Giftstoffen, die Abwehr von Infektionserregern, die Reparatur von Läsionen sowie die Aufrechterhaltung eines konstanten inneren Milieus (Homöostase). Die dafür notwendigen Anpassungsvorgänge zielen besonders auf das Verhalten des Blutes in der Endstrombahn (Mikrozirkulation) ab, da hier die »Kommunikation « der freien Zellen des Blutes mit den residenten Zellen des Gewebes stattfindet. Ist dieses Zusammenwirken gestört, kommt es zur Organdysfunktion.

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Author information

Authors and Affiliations

  1. Abteilung Anästhesiologie, Universitätsmedizinisches Zentrum Groningen Universität Groningen, Hanzeplein 1, NL-9700 RB, Groningen

    Prof. Dr. T. Scheeren

  2. Klinik u. Poliklinik f. Anästhesiologie u. Intensivtherapie, Univ.-Klinikum Rostock AäR, Schillingallee 35, 18057, Rostock

    Dr. S. M. Hergert

  3. Klinik u. Poliklinik f. Anästhesiologie u. Intensivtherapie, Univ.-Klinikum Rostock AäR, Schillingallee 35, 18057, Rostock

    Prof. Dr. G. Nöldge-Schomburg

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  1. Prof. Dr. T. Scheeren
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  2. Dr. S. M. Hergert
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  3. Prof. Dr. G. Nöldge-Schomburg
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  1. Abteilung für Transfusionsmedizin, Universitätsklinikum Rostock AöR, Ernst-Heydemann-Str. 6, 18057, Rostock

    Volker Kiefel

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Scheeren, T., Hergert, S.M., Nöldge-Schomburg, G. (2010). Kreislaufphysiologische Grundlagen. In: Kiefel, V., Mueller-Eckhardt, C. (eds) Transfusionsmedizin und Immunhämatologie. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-12765-6_3

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  • DOI: https://doi.org/10.1007/978-3-642-12765-6_3

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-12764-9

  • Online ISBN: 978-3-642-12765-6

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