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Hämatologische Probleme

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Neugeborenenintensivmedizin

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Zusammenfassung

Diese variieren in Abhängigkeit vom Gestations- und stärker vom postnatalen Alter (Ø Tab. 12.1, Ø Tab. 12.2, Ø Tab. 12.3) und können bei kapillärer Blutentnahme erheblich höher sein als bei venöser oder arterieller [85].

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Literatur

  1. Aher S, Ohlsson A (2006) Late erythropoietin for preventing red blood cell transfusion in preterm and/or low birth weight infants. Cochrane Database Syst Rev 3:CD004868

    PubMed  CAS  Google Scholar 

  2. Aher SM, Ohlsson A (2006) Early versus late erythropoietin for preventing red blood cell transfusion in preterm and/or low birth weight infants. Cochrane Database Syst Rev (3):CD004865

    PubMed  CAS  Google Scholar 

  3. Aladangady N, McHugh S, Aitchison TC, Wardrop CA, Holland BM (2006) Infants’ blood volume in a controlled trial of placental transfusion at preterm delivery. Pediatrics 117;93–8

    Article  PubMed  Google Scholar 

  4. Amir J, Metzker A, Krikler R, Reisner SH (1986) Strawberry hemangioma in preterm infants. Pediatr Dermatol 3:331–2

    Article  PubMed  CAS  Google Scholar 

  5. Andrew M, Paes B, Milner R, Johnston M, Mitchell L, Tollefsen DM, Castle V, Powers P (1988) Development of the human coagulation system in the healthy premature infant. Blood 72:1651–7

    PubMed  CAS  Google Scholar 

  6. Awonusonu FO, Pauly TH, Hutchison AA (2002) Maternal smoking and partial exchange transfusion for neonatal polycythemia. Am J Perinatol 19:349–54

    Article  PubMed  Google Scholar 

  7. Bader D, Kugelman A, Maor-Rogin N, Weinger-Abend M, Hershkowitz S, Tamir A, Lanir A, Attias D, Barak M (2001) The role of high-dose oral iron supplementation during erythropoietin therapy for anemia of prematurity. J Perinatol 21:215–20

    Article  PubMed  CAS  Google Scholar 

  8. Balk R, Emerson T, Fourrier F, Kruse JA, Mammen EF, Schuster HP, Vinazzer H (1998) Therapeutic use of antithrombin concentrate in sepsis. Semin Thromb Hemost 24:183–94

    Article  PubMed  CAS  Google Scholar 

  9. Bednarek FJ, Weisberger S, Richardson DK, Frantz ID 3rd, Shah B, Rubin LP (1998) Variations in blood transfusions among newborn intensive care units. SNAP II Study Group. J Pediatr 133:601–7

    Article  PubMed  CAS  Google Scholar 

  10. Bell EF, Strauss RG, Widness JA, Mahoney LT , Mock DM, Seward VJ, Cress GA, Johnson KJ, Kromer IJ, Zimmerman MB (2005) Randomized trial of liberal versus restrictive guidelines for red blood cell transfusion in preterm infants. Pediatrics 115:1685–91

    Article  PubMed  Google Scholar 

  11. Blanchette V, Andrew M, Perlman M, Ling E, Ballin A (1989) Neonatal autoimmune thrombocytopenia: role of high-dose intravenous immunoglobulin G therapy. Blut 59:139–44

    Article  PubMed  CAS  Google Scholar 

  12. Blanchette VS, Johnson J, Rand M (2000) The management of alloimmune neonatal thrombocytopenia. Baillieres Best Pract Res Clin Haematol 13:365–90

    Article  PubMed  CAS  Google Scholar 

  13. Blanchette VS, Kuhne T, Hume H, Hellmann J (1995) Platelet transfusion therapy in newborn infants. Transfus Med Rev 9:215–30

    Article  PubMed  CAS  Google Scholar 

  14. Brown MS, Jones MA, Ohls RK, Christensen RD (1993) Single-dose pharmacokinetics of recombinant human erythropoietin in preterm infants after intravenous and subcutaneous administration. J Pediatr 122:655–7

    Article  PubMed  CAS  Google Scholar 

  15. Bundesministerium der Justiz (2007) Gesetz zur Regelung des Transfusionswesens BGBI. I ( Bundesanzeiger 209a:2169

    Google Scholar 

  16. Bundesministerium der Justiz (2010) Bekanntmachung der Richtlinien zur Gewinnung von Blut und Blutbestandteilen und zur Anwendung von Blutprodukten (Hämotherapie) gemäß §§ 12 und 18 des Transfusionsgesetzes (TFG) Bundesanzeiger Nummer 209a

    Google Scholar 

  17. Bussel JB (2001) Alloimmune thrombocytopenia in the fetus and newborn. Semin Thromb Hemost 27:245–52

    Article  PubMed  CAS  Google Scholar 

  18. Crowley M, Kirpalani H (2010) A rational approach to red blood cell transfusion in the neonatal ICU. Curr Opin Pediatr 22:151–7

    Article  PubMed  Google Scholar 

  19. Crowther CA, Henderson-Smart DJ (2000) Vitamin K prior to preterm birth for preventing neonatal periventricular haemorrhage. Cochrane Database Syst Rev:CD000229

    Google Scholar 

  20. Dani C, Reali MF, Bertini G, Martelli E, Pezzati M, Rubaltelli FF (2001) The role of blood transfusions and iron intake on retinopathy of prematurity. Early Hum Dev 62:57–63

    Article  PubMed  CAS  Google Scholar 

  21. Dempsey EM, Barrington K (2005) Crystalloid or colloid for partial exchange transfusion in neonatal polycythemia: a systematic review and meta-analysis. Acta Paediatr 94:1650–5

    Article  PubMed  Google Scholar 

  22. De Waal KA, Baerts W, Offringa M (2006) Systematic review of the optimal fluid for dilutional exchange transfusion in neonatal polycythaemia. Arch Dis Child Fetal Neonatal Ed 91:F7–10

    Article  PubMed  Google Scholar 

  23. Forestier F, Daffos F, Catherine N, Renard M, Andreux JP (1991) Developmental hematopoiesis in normal human fetal blood. Blood 77:2360–3

    PubMed  CAS  Google Scholar 

  24. Franz AR, Pohlandt F (2001) Red blood cell transfusions in very and extremely low birthweight infants under restrictive transfusion guidelines: is exogenous erythropoietin necessary? Arch Dis Child Fetal Neonatal Ed 84:F96-F100

    Article  PubMed  CAS  Google Scholar 

  25. Franz AR, Mihatsch WA, Sander S, Kron M, Pohlandt F (2000) Prospective randomized trial of early versus late enteral iron supplementation in infants with a birth weight of less than 1301 grams. Pediatrics 106:700–6

    Article  PubMed  CAS  Google Scholar 

  26. Garcia MG, Hutson AD, Christensen RD (2002) Effect of recombinant erythropoietin on »late« transfusions in the neonatal intensive care unit: a metaanalysis. J Perinatol 22:108–11

    Article  PubMed  Google Scholar 

  27. Hosono S, Mugishima H, Fujita H, Hosono A, Minato M, Okada T, Takahashi S, Harada K (2008) Umbilical cord milking reduces the need for red cell transfusions and improves neonatal adaptation in infants born at less than 29 weeks’ gestation: a randomised controlled trial. Arch Dis Child Fetal Neonatal Ed 93:F14–9

    Article  PubMed  CAS  Google Scholar 

  28. Hosono S, Mugishima H, Fujita H, Hosono A, Okada T, Takahashi S, Masaoka N, Yamamoto T (2009) Blood pressure and urine output during the first 120 h of life in infants born at less than 29 weeks’ gestation related to umbilical cord milking. Arch Dis Child Fetal Neonatal Ed 94:F328–31

    Article  PubMed  CAS  Google Scholar 

  29. Hume H (1997) Red blood cell transfusions for preterm infants: the role of evidence-based medicine. Semin Perinatol 21:8–19

    Article  PubMed  CAS  Google Scholar 

  30. John CM, Harkensee C (2005) Thrombolytic agents for arterial and venous thromboses in neonates. Cochrane Database Syst Rev:CD004342

    Google Scholar 

  31. Kaplan C (2002) Alloimmune thrombocytopenia of the fetus and the newborn. Blood Rev 16:69–72

    Article  PubMed  CAS  Google Scholar 

  32. Keyes WG, Donohue PK, Spivak JL, Jones MD, Jr., Oski FA (1989) Assessing the need for transfusion of premature infants and role of hematocrit, clinical signs, and erythropoietin level. Pediatrics 84:412–7

    PubMed  CAS  Google Scholar 

  33. Kirpalani H, Whyte RK, Andersen C, Asztalos EV, Heddle N, Blajchman MA, Peliowski A, Rios A, LaCorte M, Connelly R, Barrington K, Roberts RS (2006) The Premature Infants in Need of Transfusion (PINT) study: a randomized, controlled trial of a restrictive (low) versus liberal (high) transfusion threshold for extremely low birth weight infants. J Pediatr 149:301–307

    Article  PubMed  Google Scholar 

  34. Kleihauer E, Hildegard B, Betke K (1957) Demonstration von fetalem Hämoglobin in den Erythrozyten eines Blutausstrichs. Klinische Wochenschrift 35:637–638

    Article  PubMed  CAS  Google Scholar 

  35. Kotto-Kome AC, Garcia MG, Calhoun DA, Christensen RD (2004) Effect of beginning recombinant erythropoietin treatment within the first week of life, among very-low-birth-weight neonates, on »early« and »late« erythrocyte transfusions: a meta-analysis. J Perinatol 24:24–9

    Article  PubMed  CAS  Google Scholar 

  36. Kreuz W, Veldmann A, Fischer D, Schlosser R, Volk WR, Ettingshausen CE (1999) Neonatal sepsis: a challenge in hemostaseology. Semin Thromb Hemost 25:531–5

    Article  PubMed  CAS  Google Scholar 

  37. Kroll H, Bein G (1999) Neonatale Autoimmunthrombrozytopenie. Dtsch Med Wochenschr 124;1435–1436

    PubMed  CAS  Google Scholar 

  38. Leung SP (2000) Multiple strawberry haemangiomas-side effect of rhuEpo? Acta Paediatr 89:890

    Article  PubMed  CAS  Google Scholar 

  39. Liu EA, Mannino FL, Lane TA (1994) Prospective, randomized trial of the safety and efficacy of a limited donor exposure transfusion program for premature neonates. J Pediatr 125:92–6

    Article  PubMed  CAS  Google Scholar 

  40. Maier RF, Metze B, Obladen M (1998) Low degree of regionalization and high transfusion rates in very low birthweight infants: a survey in Germany. J Perinat Med 26:43–8

    Article  PubMed  CAS  Google Scholar 

  41. Maier RF, Obladen M, Kattner E, Natzschka J, Messer J, Regazzoni BM, Speer CP, Fellman V, Grauel EL, Groneck P, Wagner M, Moriette G, Salle BL, Verellen G, Scigalla P (1998) High-versus low-dose erythropoietin in extremely low birth weight infants. The European Multicenter rhEPO Study Group. J Pediatr 132:866–70

    Article  PubMed  CAS  Google Scholar 

  42. Maier RF, Obladen M, Muller-Hansen I, Kattner E, Merz U, Arlettaz R, Groneck P, Hammer H, Kossel H, Verellen G, Stock GJ, Lacaze-Masmonteil T, Claris O, Wagner M, Matis J, Gilberg F (2002) Early treatment with erythropoietin beta ameliorates anemia and reduces transfusion requirements in infants with birth weights below 1000 g. J Pediatr 141:8–15

    Article  PubMed  CAS  Google Scholar 

  43. Maier RF, Obladen M, Scigalla P, Linderkamp O, Duc G, Hieronimi G, Halliday HL, Versmold HT, Moriette G, Jorch G et al. (1994) The effect of epoetin beta (recombinant human erythropoietin) on the need for transfusion in very-lowbirth-weight infants. European Multicentre Erythropoietin Study Group. N Engl J Med 330:1173–8

    Article  PubMed  CAS  Google Scholar 

  44. Maier RF, Sonntag J, Walka MM, Liu G, Metze BC, Obladen M (2000) Changing practices of red blood cell transfusions in infants with birth weights less than 1000 g. J Pediatr 136:220–4

    Article  PubMed  CAS  Google Scholar 

  45. Mercer JS, Vohr BR, Erickson-Owens DA, Padbury JF, Oh W (2010) Sevenmonth developmental outcomes of very low birth weight infants enrolled in a randomized controlled trial of delayed versus immediate cord clamping. J Perinatol 30:11–6

    Article  PubMed  CAS  Google Scholar 

  46. Mercer JS, Vohr BR, McGrath MM, Padbury JF, Wallach M, Oh W (2006) Delayed cord clamping in very preterm infants reduces the incidence of intraventricular hemorrhage and late-onset sepsis: a randomized, controlled trial. Pediatrics 117:1235–42

    Article  PubMed  Google Scholar 

  47. Mouzinho A, Rosenfeld CR, Sanchez PJ, Risser R (1994) Revised reference ranges for circulating neutrophils in very-low-birth-weight neonates. Pediatrics 94:76–82

    PubMed  CAS  Google Scholar 

  48. Mueller-Eckhardt C, Kiefel V, Grubert A (1989) High-dose IgG treatment for neonatal alloimmune thrombocytopenia. Blut 59:145–6

    Article  PubMed  CAS  Google Scholar 

  49. Neubauer AP, Voss W, Wachtendorf M, Jungmann T (2010) Erythropoietin improves neurodevelopmental outcome of extremely preterm infants. Ann Neurol 67:657–66

    PubMed  CAS  Google Scholar 

  50. Obladen M, Diepold K, Maier RF (2000) Venous and arterial hematologic profiles of very low birth weight infants. European Multicenter rhEPO Study Group. Pediatrics 106:707–11

    Article  PubMed  CAS  Google Scholar 

  51. Obladen M, Sachsenweger M, Stahnke M (1988) Blood sampling in very low birth weight infants receiving different levels of intensive care. Eur J Pediatr 147:399–404

    Article  PubMed  CAS  Google Scholar 

  52. Ohls RK, Ehrenkranz RA, Das A, Dusick AM, Yolton K, Romano E, Delaney-Black V, Papile LA, Simon NP, Steichen JJ, Lee KG (2004) Neurodevelopmental outcome and growth at 18 to 22 months’ corrected age in extremely low birth weight infants treated with early erythropoietin and iron. Pediatrics 114:1287–91

    Article  PubMed  Google Scholar 

  53. Ohls RK, Osborne KA, Christensen RD (1995) Efficacy and cost analysis of treating very low birth weight infants with erythropoietin during their first two weeks of life: a randomized, placebo-controlled trial. J Pediatr 126:421–6

    Article  PubMed  CAS  Google Scholar 

  54. Ohlsson A, Aher SM (2006) Early erythropoietin for preventing red blood cell transfusion in preterm and/or low birth weight infants. Cochrane Database Syst Rev (3):CD004863

    PubMed  CAS  Google Scholar 

  55. Ozek E, Soll R, Schimmel MS (2010) Partial exchange transfusion to prevent neurodevelopmental disability in infants with polycythemia. Cochrane Database Syst Rev:CD005089

    Google Scholar 

  56. Paul DA, Leef KH, Locke RG, Stefano JL (2002) Transfusion volume in infants with very low birth weight: a randomized trial of 10 versus 20 ml/kg. J Pediatr Hematol Oncol 24;43–6

    Article  PubMed  Google Scholar 

  57. Pereira SP, Shearer MJ, Williams R, Mieli-Vergani G (2003) Intestinal absorption of mixed micellar phylloquinone (vitamin K1) is unreliable in infants with conjugated hyperbilirubinaemia: implications for oral prophylaxis of vitamin K deficiency bleeding. Arch Dis Child Fetal Neonatal Ed 88:F113–8

    Article  PubMed  CAS  Google Scholar 

  58. Puckett RM, Offringa M (2000) Prophylactic vitamin K for vitamin K deficiency bleeding in neonates. Cochrane Database Syst Rev:CD002776

    Google Scholar 

  59. Rabe H, Alvarez JR, Lawn C, Seddon P, Amess PN (2009) A management guideline to reduce the frequency of blood transfusion in very-low-birth-weight infants. Am J Perinatol 26:179–83

    Article  PubMed  Google Scholar 

  60. Rabe H, Reynolds G, Diaz-Rossello J (2004) Early versus delayed umbilical cord clamping in preterm infants. Cochrane Database Syst Rev:CD003248

    Google Scholar 

  61. Rabe H, Reynolds G, Diaz-Rossello J (2008) A systematic review and meta-analysis of a brief delay in clamping the umbilical cord of preterm infants. Neonatology 93:138–44

    Article  PubMed  Google Scholar 

  62. Ranasinghe E, Walton JD, Hurd CM, Saul L, Smith G, Campbell K, Ouwehand WH (2001) Provision of platelet support for fetuses and neonates affected by severe fetomaternal alloimmune thrombocytopenia. Br J Haematol 113:40–2

    Article  PubMed  CAS  Google Scholar 

  63. Rayment R, Brunskill SJ, Stanworth S, Soothill PW, Roberts DJ, Murphy MF (2005) Antenatal interventions for fetomaternal alloimmune thrombocytopenia. Cochrane Database Syst Rev:CD004226

    Google Scholar 

  64. Ringer SA, Richardson DK, Sacher RA, Keszler M, Churchill WH (1998) Variations in transfusion practice in neonatal intensive care. Pediatrics 101:194–200

    Article  PubMed  CAS  Google Scholar 

  65. Romagnoli C, Zecca E, Gallini F, Girlando P, Zuppa AA (2000) Do recombinant human erythropoietin and iron supplementation increase the risk of retinopathy of prematurity? Eur J Pediatr 159:627–8

    Article  PubMed  CAS  Google Scholar 

  66. Roseff SD, Luban NL, Manno CS (2002) Guidelines for assessing appropriateness of pediatric transfusion. Transfusion 42:1398–413

    Article  PubMed  Google Scholar 

  67. Rosenkrantz TS (2003) Polycythemia and hyperviscosity in the newborn. Semin Thromb Hemost 29:515–27

    Article  PubMed  Google Scholar 

  68. Ross MP, Christensen RD, Rothstein G, Koenig JM, Simmons MA, Noble NA, Kimura RE (1989) A randomized trial to develop criteria for administering erythrocyte transfusions to anemic preterm infants 1 to 3 months of age. J Perinatol 9:246–53

    PubMed  CAS  Google Scholar 

  69. Sainio S, Jarvenpaa AL, Renlund M, Riikonen S, Teramo K, Kekomaki R (2000) Thrombocytopenia in term infants: a population-based study. Obstet Gynecol 95:441–6

    Article  PubMed  CAS  Google Scholar 

  70. Schelonka RL, Yoder BA, desJardins SE, Hall RB, Butler J (1994) Peripheral leukocyte count and leukocyte indexes in healthy newborn term infants. J Pediatr 125:603–6

    Article  PubMed  CAS  Google Scholar 

  71. Schimmel MS, Bromiker R, Soll RF (2004) Neonatal polycythemia: is partial exchange transfusion justified? Clin Perinatol 31:545–53, ix-x

    Article  PubMed  Google Scholar 

  72. Schubiger G, Berger TM, Weber R, Banziger O, Laubscher B (2003) Prevention of vitamin K deficiency bleeding with oral mixed micellar phylloquinone: results of a 6-year surveillance in Switzerland. Eur J Pediatr 162:885–8

    Article  PubMed  CAS  Google Scholar 

  73. Shannon KM, Keith JF 3rd, Mentzer WC, Ehrenkranz RA, Brown MS, Widness JA, Gleason CA, Bifano EM, Millard DD, Davis CB et al. (1995) Recombinant human erythropoietin stimulates erythropoiesis and reduces erythrocyte transfusions in very low birth weight preterm infants. Pediatrics 95:1–8

    PubMed  CAS  Google Scholar 

  74. Sharon R, Tatarsky I (1994) Low fetal morbidity in pregnancy associated with acute and chronic idiopathic thrombocytopenic purpura. Am J Hematol 46:87–90

    Article  PubMed  CAS  Google Scholar 

  75. Shirahata A, Shirakawa Y, Murakami C (1998) Diagnosis of DIC in very low birth weight infants. Semin Thromb Hemost 24:467–71

    Article  PubMed  CAS  Google Scholar 

  76. Sola MC, Del Vecchio A, Rimsza LM (2000) Evaluation and treatment of thrombocytopenia in the neonatal intensive care unit. Clin Perinatol 27:655–79

    Article  PubMed  CAS  Google Scholar 

  77. Steinmacher J, Pohlandt F, Bode H, Sander S, Kron M, Franz AR (2007) Randomized trial of early versus late enteral iron supplementation in infants with a birth weight of less than 1301 grams: neurocognitive development at 5.3 years’ corrected age. Pediatrics 120:538–46

    Article  PubMed  Google Scholar 

  78. Strauss RG (1991) Transfusion therapy in neonates. Am J Dis Child 145:904–11

    PubMed  CAS  Google Scholar 

  79. Strauss RG, Bell EF, Snyder EL, Elbert C, Crawford G, Floss A, Wilmoth PK, Rios GR, Koontz FP (1986) Effects of environmental warming on blood components dispensed in syringes for neonatal transfusions. J Pediatr 109:109–13

    Article  PubMed  CAS  Google Scholar 

  80. Strauss RG, Burmeister LF, Johnson K, Cress G, Cordle D (2000) Feasibility and safety of AS-3 red blood cells for neonatal transfusions. J Pediatr 136:215–9

    Article  PubMed  CAS  Google Scholar 

  81. Strauss RG, Burmeister LF, Johnson K, James T, Miller J, Cordle DG, Bell EF, Ludwig GA (1996) AS-1 red cells for neonatal transfusions: a randomized trial assessing donor exposure and safety. Transfusion 36:873–8

    Article  PubMed  CAS  Google Scholar 

  82. Strauss RG, Mock DM, Johnson KJ, Cress GA, Burmeister LF, Zimmerman MB, Bell EF, Rijhsinghani A (2008) A randomized clinical trial comparing immediate versus delayed clamping of the umbilical cord in preterm infants: short-term clinical and laboratory endpoints. Transfusion 48:658–65

    Article  PubMed  Google Scholar 

  83. Suzuki S, Morishita S (1998) Hypercoagulability and DIC in high-risk infants. Semin Thromb Hemost 24:463–6

    Article  PubMed  CAS  Google Scholar 

  84. Swetnam SM, Yabek SM, Alverson DC (1987) Hemodynamic consequences of neonatal polycythemia. J Pediatr 110:443–7

    Article  PubMed  CAS  Google Scholar 

  85. Thurlbeck SM, McIntosh N (1987) Preterm blood counts vary with sampling site. Arch Dis Child 62:74–5

    Article  PubMed  CAS  Google Scholar 

  86. Ultee CA, Van Der Deure J, Swart J, Lasham C, van Baar AL (2008) Delayed cord clamping in preterm infants delivered at 34 36 weeks’ gestation: a randomised controlled trial. Arch Dis Child Fetal Neonatal Ed 93:F20–3

    Article  PubMed  CAS  Google Scholar 

  87. Vamvakas EC, Strauss RG (2001) Meta-analysis of controlled clinical trials studying the efficacy of rHuEPO in reducing blood transfusions in the anemia of prematurity. Transfusion 41:406–15

    Article  PubMed  CAS  Google Scholar 

  88. Van Winckel M, De Bruyne R, Van De Velde S, Van Biervliet S (2009) Vitamin K, an update for the paediatrician. Eur J Pediatr 168:127–34

    Article  PubMed  Google Scholar 

  89. Von Kries R (1999) Oral versus intramuscular phytomenadione: safety and efficacy compared. Drug Saf 21:1–6

    Article  Google Scholar 

  90. Von Kries R, Hachmeister A, Gobel U (2003) Oral mixed micellar vitamin K for prevention of late vitamin K deficiency bleeding. Arch Dis Child Fetal Neonatal Ed 88:F109–12

    Article  Google Scholar 

  91. Walka MM, Sonntag J, Kage A, Dudenhausen JW, Obladen M (1998) Complete blood counts from umbilical cords of healthy term newborns by two automated cytometers. Acta Haematol 100:167–73

    Article  PubMed  CAS  Google Scholar 

  92. Warwood TL, Ohls RK, Wiedmeier SE, Lambert DK, Jones C, Scoffield SH, Neeraj G, Veng-Pedersen P, Christensen RD (2005) Single-dose darbepoetin administration to anemic preterm neonates. J Perinatol 25:725–30

    Article  PubMed  CAS  Google Scholar 

  93. Whyte RK, Kirpalani H, Asztalos EV, Andersen C, Blajchman M, Heddle N, LaCorte M, Robertson CM, Clarke MC, Vincer MJ, Doyle LW, Roberts RS (2009) Neurodevelopmental outcome of extremely low birth weight infants randomly assigned to restrictive or liberal hemoglobin thresholds for blood transfusion. Pediatrics 123:207–13

    Article  PubMed  Google Scholar 

  94. Widness JA, Seward VJ, Kromer IJ, Burmeister LF, Bell EF, Strauss RG (1996) Changing patterns of red blood cell transfusion in very low birth weight infants. J Pediatr 129:680–7

    Article  PubMed  CAS  Google Scholar 

  95. Williamson LM, Hackett G, Rennie J, Palmer CR, Maciver C, Hadfield R, Hughes D, Jobson S, Ouwehand WH (1998) The natural history of fetomaternal alloimmunization to the platelet-specific antigen HPA -1a (PlA1, Zwa) as determined by antenatal screening. Blood 92:2280–7

    PubMed  CAS  Google Scholar 

  96. Wiswell TE, Cornish JD, Northam RS (1986) Neonatal polycythemia: frequency of clinical manifestations and other associated findings. Pediatrics 78:26–30

    PubMed  CAS  Google Scholar 

  97. Wood A, Wilson N, Skacel P, Thomas R, Tidmarsh E, Yale C, de Silva M (1995) Reducing donor exposure in preterm infants requiring multiple blood transfusions. Arch Dis Child Fetal Neonatal Ed 72:F29–33

    Article  PubMed  CAS  Google Scholar 

  98. Zaffanello M, Franchini M, Rugolotto S (2003) Recombinant human erythropoietin might induce strawberry haemangiomas in very-low-birthweight preterm infants. Acta Paediatr 92:1353–4

    Article  PubMed  CAS  Google Scholar 

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  1. Klinik für Kinder- und Jugendmedizin, Universitätsklinikum Gießen und Marburg GmbH Standort Marburg, Baldinger Strasse, 35033, Marburg

    Prof. Dr. med. Rolf F. Maier (Direktor)

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  1. Klinik für Kinder- und Jugendmedizin, Universitätsklinikum Gießen und Marburg GmbH Standort Marburg, Baldinger Strasse, 35033, Marburg

    Rolf F. Maier (Direktor) (Direktor)

  2. Klinik für Neonatologie, Charité Virchow-Klinikum, Augustenburger Platz 1, 13353, Berlin

    Michael Obladen (em. Direktor) (em. Direktor)

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Maier, R.F. (2011). Hämatologische Probleme. In: Maier, R.F., Obladen, M. (eds) Neugeborenenintensivmedizin. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-01069-9_12

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