Auszug
ACE-Hemmer und Angiotensinrezeptorantagonisten gehören zu den besonders erfolgreichen Arzneimitteln zur Behandlung von Hypertonie, Herz- und Nierenkrankheiten.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
Literatur
Anlauf M, Weber F (2005): Bedeutung der Therapie mit Antihypertensiva für die kardiovaskuläre Prävention. In: Bundesärztekammer (Hrsg.): Fortschritt und Fortbildung in der Inneren Medizin. Band 29. Deutscher Ärzteverlag Köln.
Anlauf M. (2006): Beurteilung von Therapien mit der “number needed to treat”. Deutsches Ärzteblatt 103: A3254–A3258.
Arzneimittelkommission der Deutschen Ă„rzteschaft (2004): Empfehlungen zur Therapie der arteriellen Hypertonie. 2. Auflage, Arzneiverordnung in der Praxis, Band 31, Sonderheft 2 (Therapieempfehlungen), Internet: www.akdae. de/35/74_Hypertonie_2004_2Auflage.pdf
Barnett AH, Bain SC, Bouter P, Karlberg B et al (2004): Angiotensin-receptor blockade versus converting-enzyme inhibition in type 2 diabetes and nephropathy. N Engl J Med 351: 1952–1961.
Blood Pressure Lowering Treatment Trialists’ Collaboration (2000): Effects of ACE inhibitors, calcium antagonists, and other blood-pressure-lowering drugs: results of prospectively designed overviews of randomised trials. Lancet 356: 1955–1964.
Blood Pressure Lowering Treatment Trialists’ Collaboration (2007): Blood Pressure dependent and independent effects of agents that inhibit the renin-angiotensin system. J. Hypertension 25: 951–958.
Casas JP, Chua W, Loukogeorgakis S, Vallance P, Smeeth L, Hingorani AD, MacAllister RJ (2005): Effect of inhibitors of the renin-angiotensin system and other antihypertensive drugs on renal outcomes: systematic review and meta-analysis. Lancet 366: 2026–2033.
Cohn JN, Tognoni G for the Valsartan Heart Failure Trial Investigators (2001): A randomized trial of the angiotensin-receptor blocker valsartan in chronic heart failure. N Engl J Med 345: 1667–1675.
CONSENSUS Trial Study Group (1987): Effects of enalapril on mortality in severe congestive heart failure: Results of the Cooperative North Scandinavian Enalapril Survival Study (CONSENSUS). N Engl J Med 316: 1429–1435.
Dahlöf B, Devereux RB, Kjeldsen SE, Julius S, Beevers G, Faire U et al for The LIFE Study Group (2002): Cardiovascular morbidity and mortality in the losartan intervention for endpoint reduction in hypertension study (LIFE): a randomised trial against atenolol. Lancet 359: 995–1003.
Davis BD, Piller LB, Cutler JA, Curt Furberg C et al. (2006): Role of Diuretics in the Prevention of Heart Failure. The Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial. Circulation 113: 2201–2210.
Dickstein K, Kjekshus J, and the OPTIMAAL Steering Committee, for the OPTI-MAAL Study Group (2002): Effects of losartan and captopril on mortality and morbidity in high-risk patients after acute myocardial infarction: the OPTI-MAAL randomised trial. Lancet 360: 752–760.
Elliott WJ, Meyer PM (2007): Incident diabetes in clinical trials of antihypertensive drugs: a network meta-analysis. Lancet 369: 201–207
Fiather MD, Yusuf S, Kober L, Pfeffer M et al (2000): Long-term ACE-inhibitor therapy in patients with heart failure or left-ventricular dysfunction: a systematic overview of data from individual patients. Lancet 355: 1575–1581.
Granger CB, McMurray JJV, Yusuf S, Held P et al (2003): Effects of candesartan in patients with chronic heart failure and reduced left-ventricular systolic function intolerant to angiotensin-converting-enzyme inhibitors: the CHARM-Alternative trial. Lancet 362: 772–776.
Julius S, Kjeldsen SE, Weber M, Brunner HR, Ekman S, Hansson L, Hua T, Laragh J, McInnes GT, Mitchell L, Plat F, Schork A, Smith B, Zanchetti A; VALUE trial group (2004): Outcomes in hypertensive patients at high cardiovascular risk treated with regimens based on valsartan or amlodipine: the VALUE randomised trial. Lancet 363: 2022–2031.
Julius S, Nesbitt SD, Egan BM. for the Trial of Preventing Hypertension (TROPHY) Study Investigators (2006): Feasibility of treating prehypertension with an angiotensin-receptor blocker. N Engl J Med. 354: 1685–1697.
Kizer JR, Dahlöf B, Kjeldsen SE, Julius S et al. (2005): Stroke reduction in hypertensive adults with cardiac hypertrophy randomized to losartan versus atenolol. The Losartan Intervention For Endpoint Reduction in Hypertension Study. Hypertension 45: 46–52.
Laverman GD, Navis G, Henning RH, de Jong D, de Zeeuw D (2002): Dual reninangiotensin system blockade at optimal doses for proteinuria. Kidney Int 62: 1020–1025.
Levy BI (2004): Can angiotensin II Type 2 receptors have deleterious effects in cardiovascular disease? Circulation 109: 8–13.
Lewis EJ, Hunsicker LG, Bain RP, Rohde RD for the Collaborative Study Group (1993): The effect of angiotensin-converting-enzyme inhibition on diabetic nephropathy. N Engl J Med 329: 1456–1462.
Lithell H, Hansson L, Skoog I, Elmfeldt D, Hofman A, Olofsson B et al for the SCOPE Study Group (2003): The Study on Cognition and Prognosis in the Elderly (SCOPE): principal results of a randomized double-blind intervention trial. J Hypertens 21: 875–886.
Malacco E, Santonastaso M, Vari NA, Gargiulo A, Spagnuolo V, Bertocchi F, Palatini P; Blood Pressure Reduction and Tolerability of Valsartan in Comparison with Lisinopril Study (2004): Comparison of valsartan 160 mg with lisinopril 20 mg, given as monotherapy or in combination with a diuretic, for the treatment of hypertension: the Blood Pressure Reduction and Tolerability of Valsartan in Comparison with Lisinopril (PREVAIL) study. Clin Ther 26: 855–865.
Mann JF, Ritz E, Kunz R (2006): Renoprotective effects of renin-angiotensin-system inhibitors. Lancet 367: 900.
Maschio G, Albert D, Ganin G, Locatelli F, Mann JFE et al (1996): Effect of the angiotensin-converting-enzyme inhibitor benazepril on the progression of chronic renal insufficiency. N Engl J Med 334: 939–945.
McMurray JJV, Östergren J, Swedberg K, Granger CB et al (2003): Effects of candesartan in patients with chronic heart failure and reduced left-ventricular systolic function taking angiotensin-converting-enzyme inhibitors: the CHARM-Added trial. Lancet 362: 767–771.
Mogensen CE, Neldam S, Tikkanen I, Oren S, Viskoper R, Watts RW, Cooper ME (2000): Randomised controlled trial of dual blockade of renin-angiotensin system in patients with hypertension, microalbuminuria, and non-insulin dependent diabetes: the Candesartan And Lisinopril Microalbuminuria (CALM) Study. Brit Med J 321: 1440–1444.
National National Collaborating Centre for Chronic Conditions (2006): Hypertension: management of hypertension in adults in primary care: partial update. London: Royal College of Physicians. Internet: http://guidance.nice.org.uk/ CG34/guidance/pdf/English
Pfeffer MA, McMurray JJV, Velazquez EJ, Rouleau J-L et al for the Valsartan in Acute Myocardial Infarction Trial Investigators (2003a): Valsartan, captopril, or both in myocardial infarction complicated by heart failure, left ventricular dysfunction, or both. N Engl J Med 349: 1893–1906.
Pfeffer MA, Swedberg K, Granger CB, Held P et al (2003b): Effects of candesartan on mortality and morbidity in patients with chronic heart failure: the CHARM-Overall programme. Lancet 362: 559–766.
Pitt B, Poole-Wilson PA, Segal R, Martinez FA et al (2000): Effect of losartan compared with captopril on mortality in patients with symptomatic heart failure: randomised trial — the Losartan Heart Failure Survival Study ELITE II. Lancet 355: 1582–1587.
Pitt B (2004): ACE inhibitors for patients with vascular disease without left ventricular dysfunction — may they rest in PEACE? N Engl J Med 351: 2115–2117.
PROGRESS Collaborative Group (2001): Randomised trial of a perindopril-based blood-pressure-lowering regimen among 6,105 individuals with previous stroke or transient ischaemic attack. Lancet 358: 1033–1041.
Ruggenenti P, Fassi A, Ilieva AP, Bruno S, Iliev IP et al for the Bergamo Nephrologic Diabetes Complications Trial (BENEDICT) Investigators (2004): Preventing microalbuminuria in type 2 diabetes. N Engl J Med 351: 1941–1951.
Saunders E, Weir MR, Kong BW, Hollifield J, Gray J, Vertes V et al (1990): A comparison of the efficacy and safety of abeta-blocker, a calcium channel blocker, and a converting enzyme inhibitor in hypertensive blacks. Arch Intern Med 150: 1707–1713.
Schmieder RE, Hilgers KF, Schlaich MP, Schmidt MW (2007): Renin-angiotensin system and cardiovascular risk. Lancet 369: 1208–1219.
Schrader J, Lüders S, Kulschewski A, Hammersen F et al. for the MOSES Study Group (2005): Morbidity and Mortality After Stroke, Eprosartan Compared With Nitrendipine for Secondary Prevention Principal Results of a Prospective Randomized Controlled Study (MOSES). Stroke 36:1218–1226.
Svensson P, de Faire U, Sleight P, Yusuf S, Jan Östergren J (2001): Comparative effects of ramipril on ambulatory and office blood pressures. A HOPE substudy. Hypertension 38: e28–e32.
Teo KK, Yusuf S, Pfeffer M, Torp-Pedersen C, Kober L, Hall A et al and the ACE Inhibitors Collaborative Group (2002): Effects of long-term treatment with angiotensin-converting enzyme inhibitors in the presence or absence of aspirin: a systematic review. Lancet 360: 1037–1043.
The ALLHAT Officers and Coordinators for the ALLHAT Collaborative Research Group (2002): Major outcomes in high-risk hypertensive patients randomized to angiotensin-converting enzyme inhibitor or calcium channel blocker vs diuretic. The Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT). JAMA 288: 2981–2997.
The DREAM Trial Investigators (2006): Effect of ramipril on the incidence of diabetes. N Engl J Med 355: 1551–1562.
The GISEN Group (1997): Randomised placebo-controlled trial of effect of ramipril on decline in glomerular filtration rate and risk of terminal renal failure in proteinuric, non-diabetic nephropathy. Lancet 349: 1857–1863.
The Heart Outcomes Prevention Evaluation (HOPE) Study Investigators (2000): Effects of an angiotensin-converting-enzyme inhibitor, Ramipril, on cardiovascular events in high-risk patients. N Engl J Med 342: 145–153.
Verma S, Strauss M (2004): Angiotensin receptor blockers and myocardial infarction. These drugs may increase myocardial infarction — and patients may need to be told. BMJ 329: 1248–1249.
Wachteil K, Hornestam B, Lehto M, Slotwiner DJ et al (2005a): Cardiovascular morbidity and mortality in hypertensive patients with a history of atrial fibrillation: The Losartan Intervention For End Point Reduction in Hypertension (LIFE) study. J Am Coll Cardiol. 45: 705–711.
Wachtell K, Lehto M, Gerdts E, Olsen MH et al (2005b): Angiotensin II receptor blockade reduces new-onset atrial fibrillation and subsequent stroke compared to atenolol: the Losartan Intervention For End Point Reduction in Hypertension (LIFE) study. J Am Coll Cardiol. 45: 712–719.
White HD (2003): Commentary. Candesartan and heart failure: the allure of CHARM. Lancet 362: 754–755.
Wing LMH, Reid MC, Ryan P, Beilin LJ et al for the Second Australian National Blood Pressure Study Group (2003): A comparison of outcomes with angiotensin-converting-enzyme inhibitors and diuretics for hypertension in the elderly. N Engl J Med 348: 583–592.
Yusuf S (2002): From the HOPE to the ONTARGET and the TRANSCEND studies: challenges in improving prognosis. Am J Cardiol 89(2A): 18A–25A.
Yusuf S, Pfeffer MA, Swedberg K, Granger CB et al (2003): Effects of candesartan in patients with chronic heart failure and preserved left-ventricular ejection fraction: the CHARM-Preserved Trial. Lancet 362: 777–781.
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2008 Springer Medizin Verlag Heidelberg
About this chapter
Cite this chapter
Anlauf, M. (2008). ACE-Hemmer und Angiotensinrezeptorantagonisten. In: Schwabe, U., Paffrath, D. (eds) Arzneiverordnungs-Report 2007. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-72548-0_5
Download citation
DOI: https://doi.org/10.1007/978-3-540-72548-0_5
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-540-72547-3
Online ISBN: 978-3-540-72548-0
eBook Packages: Medicine (German Language)