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Antimykotika

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Arzneiverordnungs-Report 2007

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Die Verordnungen der Antimykotika haben sich 2006 insgesamt auf dem niedrigen Niveau der beiden Vorjahre gehalten, in denen sie als Folge des GKV-Modernisierungs-Gesetzes (GMG) und des damit verbundenen Verordnungsausschlusses nicht verschreibungspflichtiger Arzneimittel aus der Erstattungspflicht der GKV um ca. 50% zurückgegangen waren. Topische Monopräparate wurden 2006 insgesamt nochmals um 12% seltener verordnet als 2005. Auch die oralen Antimykotika waren um 5% rückläufig. Die Verordnungen topischer Kombinationspräparate blieben dagegen praktisch unverändert. Insgesamt sind die Veränderungen innerhalb der Gruppen marginal und basieren im Wesentlichen auf wirtschaftlichen Entscheidungen. Über in den beiden Vorjahren hinausgehende Substitutionseffekte lassen sich 2006 nicht festmachen.

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Literatur

  • Akpan, A, Morgan R (2002): Oral candidiasis. Postgrad Med J 78: 455–459.

    Article  PubMed  CAS  Google Scholar 

  • Alston SJ, Cohen BA, Braun M (2003): Persistent and recurrent tinea corporis in children treated with combination antifungal/corticosteroid agents. Pediatrics 111:201–203.

    Article  PubMed  Google Scholar 

  • Arzneimittelkommsission der deutsche Ärzteschaft (2006) Psychiatrische Reaktionen nach Terninafin (Lamisil©). Dtsch Ärztebl 103: A3432.

    Google Scholar 

  • Baran R, Kaoukhov A (2005): Topical antifungal drugs fort he treatment ofonychomycosis: an overview of current strategies for monotherapy and combination therapy. J Eur Acad Dermatol Venerol 19: 21–29.

    Article  CAS  Google Scholar 

  • Bell-Syer SEM, Hart R, Crawford F, Torgerson DJ, Tyrell W, Russell I (2006): Oral treatments for fungal infections of the skin of the foot (Cochrane Review). In: The Cochrane Library, Issue 1 2006. Oxford: Update Software.

    Google Scholar 

  • Bennett ML, Fleischer AB, Loveless JW, Feldman SR (2000): Oral griseofulvin remains the treatment of choice for tinea capitis in children. Ped Dermatol 17: 304–309.

    Article  CAS  Google Scholar 

  • Blaschke-Hellmessen R, Buchmann H, Schwarze R (1996): Einfluß oral verabreichter Polyenantibiotika auf die Hefepilzbesiedlung des Darmtraktes: Möglichkeiten und Grenzen. Mycoses 39(Suppl 1): 33–39.

    PubMed  Google Scholar 

  • Bristow IR, Baran R (2006): Topical and oral combination therapy for toenail onychomycosis. An updated review. J Am Podiatr Med Associat 96: 116–119.

    Google Scholar 

  • Casciano J, Amaya K, Doyle J, Arikian S, Shear N, Haspel M, Kahler K (2003): Economic analysis of oral and topical therapies for onychomycosis of the toenails and fingernails. Manag Care 12: 47–54.

    PubMed  Google Scholar 

  • Crawford F, Young P, Godfrey C, Bell-Syer SEM, Hart R, Brunt E, Russel I (2002): Oral treatments for toenail onychomycosis. Arch Dermatol 138: 811–816.

    Article  PubMed  CAS  Google Scholar 

  • Crawford F, Hart R, Bell-Syer S, Torgerson D, Young P, Russell I (2006): Topical treatments for fungal infections of the skin and nails of the foot (Cochrane Review). In: The Cochrane Library, Issue 1, 2006. Oxford: Update Software.

    Google Scholar 

  • Darkes MJM, Scott LJ, Goa KL (2003): Terbinafine. A review of its use in onychomycosis in adults. Am J Clin Dermatol 4: 39–65.

    Article  PubMed  Google Scholar 

  • Deutsche Dermatologische Gesellschaft und Deutschsprachige Mykologische Gesellschaft (2004): Tinea der freien Haut. AWMF-Leitlinien-Register Nr. 013–002. http://leitlinien.net/

    Google Scholar 

  • Devaraj A, O’Beirne JP, Veasey R, Dunk A (2002): Interaction between warfarin and topical miconazole cream. Br Med J 325: 77.

    Article  CAS  Google Scholar 

  • Ellis D (2002): Amphotericin B: spectrum and resistance. J Antimicrob Chemother 49(Suppl S1): 7–10.

    PubMed  CAS  Google Scholar 

  • Erbagci Z (2004): Topical therapy for dermatophytoses. Should corticosteroids be included? Am J Clin Dermatol 5: 375–384.

    Article  PubMed  Google Scholar 

  • Fleischer AB, Feldman SR (1999): Prescription of high-potency corticosteroid agents and clotrimazole-betamethasone dipropionate by pediatricians. Clin Ther 10: 1725–1731.

    Article  Google Scholar 

  • Gemeinsamer Bundesausschuss (2007): Richtlinien des Bundesausschusses der Ärzte und Krankenkassen über die Verordnung von Arzneimitteln in der vertragsärztlichen Versorgung („Arzneimittel-Richtlinien/AMR“) in der Fassung vom 31. August 1993 veröffentlicht im Bundesanzeiger 1993, Nr. 246: S. 11155 zuletzt geändert am 18. Januar 2007 veröffentlicht im Bundesanzeiger 2007; Nr. 70: S. 3821 in Kraft getreten am 14. April 2007. http://www.g-ba.de/down-loads/36-232-3/RL-AMR-2006-10-17.pdf.

    Google Scholar 

  • Goa KL, Barradell LB (1995): Fluconazole. An update of its pharmacodynamic and pharmacokinetic properties and therapeutic use in major superficial and systemic mycoses in immunocompromised patients. Drugs 50: 658–690.

    Article  PubMed  CAS  Google Scholar 

  • Gøtzsche PC, Johansen HK (2006): Nystatin prophylaxis and treatment in severely immunodepresses patients (Cochrane Review): In: The Cochrane Library, Issue 1 2006. Oxford: Update Software.

    Google Scholar 

  • Gupta AK (2002): Treatment of dermatophyte toenail onychomycosis in the United States. A pharmacoeconomic analysis. J Am Pediatr Med Assoc 92: 272–286.

    Google Scholar 

  • Gupta AK, Cooper EA, Ryder JE, Nicol KA, Chow M, Chaudhry MM (2004): Optimal management of fungal infections of the skin, hair, and nails. Am J Clin Dermatol 5: 225–237.

    Article  PubMed  Google Scholar 

  • Gupta AK, Skinner AR (2003): Ciclopirox fort he treatment of superficial fungal infections: a review. Int J Dermatol 42(Suppl 1): 3–9.

    Article  PubMed  CAS  Google Scholar 

  • Haria M, Bryson HM, Goa KL (1996): Itraconazole. A reappraisal of its pharmacological properties and therapeutic use in the management of superficial fungal infections. Drugs 51: 585–620.

    Article  PubMed  CAS  Google Scholar 

  • Haugh M, Helou S, Boissel JP, Cribier BJ (2002): Terbinafine in fungal infections of the nails: a meta-analysis of randomized clinical trials. Br J Dermatol 147: 118–121.

    Article  PubMed  CAS  Google Scholar 

  • Heel RC, Brogden RN, Carmine A, Morley PA, Speight TM, Avery GS (1982) Ketoconazole: a review of its therapeutic efficacy in superficial and systemic fungal infections. Drugs 23: 1–36.

    Article  PubMed  CAS  Google Scholar 

  • Hengge UR, Ruzicka T, Schartz RA, Cork MJ (2006): Adverse effects of topical glucocorticosteroids. J Am Acad Dermatol 54: 1–15.

    Article  PubMed  Google Scholar 

  • Ho KM, Rochford SA, John GJ (2005): The use of topical nonabsorbable gastrointestinal antifungal prophylaxis to prevent fungal infections in critically ill immunocompetent patients: A meta analysis. Crit Care Med 33: 2383–2392.

    Article  PubMed  CAS  Google Scholar 

  • Lacour M, Zunder T, Huber R, Sander A, Daschner F, Frank U (2002): The pathogenic significance of intestinal Candida colonization — A systematic review from an interdisciplinary and environmental medical point of view. Int J Hyg Environ Health 205: 257–268.

    Article  PubMed  Google Scholar 

  • Lecha M, Effendy I, Feuilhade de Chauvin M, Di Chiacchio N, Baran R (2005): Treatment options — development of consensus guidelines. J Eur Acad Dermatol Venereol 19(suppl 1): 25–33.

    Article  PubMed  Google Scholar 

  • Mayser P, Hensel J, Thoma W, Podobinska M, Geiger M, Ulbricht H Haak T (2004). Prevalence of fungal foot infections in patients with diabetes mellitus type 1 — underestimation of moccasin-type tinea. Exp Clin Endocrinol Diabetes 112: 264–268.

    Article  PubMed  CAS  Google Scholar 

  • Möhrenschlager M, Seidl HP, Ring J, Abeck D (2005): Pediatric tinea capitis. Recognition and management. Am J Clin Dermatol 6: 203–213.

    Article  PubMed  Google Scholar 

  • Patton LL, Bonito AJ, Shugars DA (2001): A systematic review of the effectiveness of antifungal drugs for the prevention and treatment of oropharyngeal candidiasis in HIV-positive patients. Oral Surg Oral Med Pathol Oral Radiol Endod 92: 170–179.

    Article  CAS  Google Scholar 

  • Pemberton MN, Oliver RJ, Theaker ED (2004): Miconazole oral gel and drug interactions. Br Dent J 196:529–531.

    Article  PubMed  CAS  Google Scholar 

  • Ring J, Fröhlich HH (1985): Wirkstoffe in der dermatologischen Therapie, 2. Aufl Springer-Verlag, Berlin, Heidelberg, New York, Tokyo, pp 133–136 und 211–213.

    Google Scholar 

  • Roberts DT, Taylor WD, Boyle J (2003): Guidelines for treatment of onychomycosis. Br J Dermatol 148: 402–410.

    Article  PubMed  CAS  Google Scholar 

  • Roberts BJ, Friedlander SF (2005): Tinea capitis: a treatment update. Pediatr Ann 34: 191–200.

    PubMed  Google Scholar 

  • Ship JA, Vissink A, Challacombe S (2007) Use of prophylactic antifungals in the immunocompromised host. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 103(suppl 1): S6.el–S6.el4.

    Google Scholar 

  • Sigurgeirsson B, Elewski BE, Rich PA, Opper C, Cai B, Nyirady J, Bakshi R (2006): Intermittent versus continuous terbinafine in the treatment of toenail onychomycosis: A randomaized, double-blind comparison. J Dermatol Treatm 17: 38–44.

    Article  CAS  Google Scholar 

  • Sigurgeirsson B, Olafsson JH, Steinsson JB, Paul C, Billstein S, Evans EGV (2002): Long-term effectiveness of treatment with terbinafine vs itraconazole in onychomycosis. Arch Dermatol 138: 353–357.

    Article  PubMed  CAS  Google Scholar 

  • Stille W, Brodt HR, Groll AH, Just-Nübling G (2005): Antibiotika-Therapie. Klinik und Praxis der antiinfektiösen Behandlung, 11. Auflage. Schattauer, Stuttgart-New York, S. 347–352.

    Google Scholar 

  • Thirion DJ, Zanetti LA (2000): Potentiation of warfarin’s hypoprothrombinemic effect with miconazole vaginal suppositories. Pharmacotherapy 20: 98–99.

    Article  PubMed  CAS  Google Scholar 

  • Venkatakrishnan K, von Moltke LL, Greenblatt DJ (2000): Effects of the antifungal agents on oxidative drug metabolism. Clin Pharmacokinet 38: 111–180.

    Article  PubMed  CAS  Google Scholar 

  • Warshaw EM, Fett DD, Bloomfield HE, Grill JP, Nelson DB, Quintero V, Carver SM, Zielke GR, Lederle FA (2005): Pulse versus continuous terbinafine for onychomycosis: a randomized, double-blind, controlled study. J Am Acad Dermatol 53: 578–584.

    Article  PubMed  Google Scholar 

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Authors and Affiliations

  1. Institut für Pharmakologie der Universität zu Köln, Gleueler Straße 24, 50924, Köln

    Prof. Dr. rer. nat. Uwe Fricke

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  1. Prof. Dr. rer. nat. Uwe Fricke
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Editors and Affiliations

  1. Pharmakologisches Institut der Universität Heidelberg, Im Neuenheimer Feld 366, 69120, Heidelberg

    Ulrich Schwabe

  2. AOK Schleswig-Holstein Die Gesundheitskasse, Edisonstraße 70, 24145, Kiel

    Dieter Paffrath

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© 2008 Springer Medizin Verlag Heidelberg

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Fricke, U. (2008). Antimykotika. In: Schwabe, U., Paffrath, D. (eds) Arzneiverordnungs-Report 2007. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-72548-0_17

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  • DOI: https://doi.org/10.1007/978-3-540-72548-0_17

  • Publisher Name: Springer, Berlin, Heidelberg

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