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Antiepileptika

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Arzneiverordnungs-Report 2007

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Entsprechend den derzeitigen Therapieempfehlungen konzentrieren sich 51% der Antiepileptikaverordnungen auf die beiden Standardtherapeutika Carbamazepin und Valproinsäure.

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Literatur

  • Attal N, Cruccu G, Haanpää M, Hansson P, Jensen TS, Nurmikko T, Sampaio C, Sindrup S, Wiffen P (2006): EFNS guidelines on pharmacological treatment of neuropathic pain. Eur J Neurol 13: 1153–1169.

    Article  PubMed  CAS  Google Scholar 

  • Backonja M, Beydoun A, Edwards KR, Schwartz SL, Fonseca V, Hes M, et al. for the Gabapentin Diabetic Neuropathy Study Group (1998): Gabapentin for the symptomatic treatment of painful neuropathy in patients with diabetes mellitus. JAMA 280: 1831–1836.

    Article  PubMed  CAS  Google Scholar 

  • Beydoun A (1999): Monotherapy trials with gabapentin for partial epilepsy. Epilepsia40(Suppl6):S13–S16.

    Article  PubMed  CAS  Google Scholar 

  • Brodie MJ (2004): Pregabalin as adjunctive therapy for partial seizures. Epilepsia 45Suppl 6: 19–27.

    Article  PubMed  CAS  Google Scholar 

  • Brodie MJ, Perucca E, Ryvlin P, Ben-Menachem E, Meencke HJ (2007): Comparison of levetiracetam and controlled-release carbamazepine in newly diagnosed epilepsy. Neurology 68: 402–408.

    Article  PubMed  CAS  Google Scholar 

  • Charatan F (2002): Doctor sues company over unethical marketing. Brit Med J 324: 1234.

    Article  PubMed  Google Scholar 

  • Dooley M, Plosker GL (2000): Levetiracetam. A review of its adjunctive use in the management of partial onset seizures. Drugs 60: 871–893.

    Article  PubMed  CAS  Google Scholar 

  • Eisenberg E, River Y, Shifrin A, Krivoy N (2007): Antiepileptic drugs in the treatment of neuropathic pain. Drugs 67: 1265–1289.

    Article  PubMed  CAS  Google Scholar 

  • European Medicines Agency (2004): Europäischer öffentlicher Beurteilungsbericht (EPAR) Lyrica. Scientific discussion. Internet: www.emea.europa.eu/humandocs/PDFs/EPAR/lyrica/084504en6.pdf

    Google Scholar 

  • French JA, Kanner AM, Bautista J, Abou-Khalil B, Browne T, Harden CL, Theodore WH, Bazil C, Stern J, Schachter SC, Bergen D, Hirtz D, Montouris GD, Nespeca M, Gidal B, Marks WJ Jr, Turk WR, Fischer JH, Bourgeois B, Wilner A, Faught RE Jr, Sachdeo RC, Beydoun A, Glauser TA; American Academy of Neurology Therapeutics and Technology Assessment Subcommittee; American Academy of Neurology Quality Standards Subcommittee; American Epilepsy Society Quality Standards Subcommittee; American Epilepsy Society Therapeutics and Technology Assessment Subcommittee (2004): Efficacy and tolerability of the new antiepileptic drugs, I: Treatment of new-onset epilepsy: report of the TTA and QSS Subcommittees of the American Academy of Neurology and the American Epilepsy Society. Epilepsia 45: 401–409.

    Article  PubMed  CAS  Google Scholar 

  • Gamble CL, Williamson PR, Marson AG (2006): Lamotrigine versus carbamazepine monotherapy for epilepsy. Cochrane Database Syst Rev 25(1):CD001031.

    Google Scholar 

  • Glauser T, Ben-Menachem E, Bourgeois B, Cnaan A, Chadwick D, Guerreiro C, Kalviainen R, Mattson R, Perucca E, Tomson T (2006): ILAE Treatment Guidelines: Evidence-based analysis of antiepileptic drug efficacy and effectiveness as initial monotherapy for epileptic seizures and syndromes. Epilepsia 47: 1094–1120.

    Article  PubMed  Google Scholar 

  • Goa KL, Ross SR, Chrisp P (1993): Lamotrigine. A review of its pharmacological properties and clinical efficacy in epilepsy. Drugs 46: 152–176.

    Article  PubMed  CAS  Google Scholar 

  • Groß-Selbeck G (1995): Treatment of „benign“ partial epilepsies of childhood, including atypical forms. Neuropediatrics 26: 45–50.

    Article  PubMed  Google Scholar 

  • Hitiris N, Brodie MJ (2006): Modern antiepileptic drugs: guidelines and beyond. Curr Opin Neurol 19: 175–180.

    Article  PubMed  Google Scholar 

  • Hufnagel A, Noachtar S (1998): Epilepsien und ihre medikamentöse Behandlung. In: Brandt T, Dichgans J, Diener HC (Hrsg): Therapie und Verlauf neurologischer Erkrankungen. 3. Aufl., Kohlhammer, Stuttgart, Berlin, Köln, S. 179–203.

    Google Scholar 

  • Jette NJ, Marson AG, Kadir ZA, Hutton JL (2000): Topiramate for drug-resistant partial epilepsy. Cochrane Database Syst Rev 2: CD001417.

    PubMed  Google Scholar 

  • Kassenärztliche Bundesvereinigung (2007): Wirkstoff AKTUELL. Pregabalin (Lyrica© Hartkapseln).Internet: www.kbv.de/publikationen/116.html

    Google Scholar 

  • LaRoche SM, Helmers SL (2004): The new antiepileptic drugs: scientific review. JAMA 291: 605–614.

    Article  PubMed  CAS  Google Scholar 

  • Lynch BA, Lambeng N, Nocka K, Kensel-Hammes P, Bajjalieh SM, Matagne A, Fuks B (2004): The synaptic vesicle protein SV2A is the binding site for the antiepileptic drug levetiracetam. PNAS 101: 9861–9866.

    Article  PubMed  CAS  Google Scholar 

  • Marson AG, Al-Kharusi AM, Alwaidh M, Appleton R, Baker GA, Chadwick DW, Cramp C, Cockerell OC, Cooper PN, Doughty J, Eaton B, Gamble C, Goulding PJ, Howell SJL, Hughes A, Jackson M, Jacoby A, Kellett M, Lawson GR, Leach JP, Nicolaides P, Roberts R, Shackley P, Shen J, Smith DS, Smith PEM, Tudor Smith C, Vanoli A, Williamson PR, on behalf of the SANAD Study group (2007a): The SANAD study of effectiveness of carbamazepine, gabapentin, lamotrigine, oxcarbazepine, or topiramate for treatment of partial epilepsy: an unblinded randomised controlled trial. Lancet 369: 1000–1015.

    Article  PubMed  CAS  Google Scholar 

  • Marson AG, Al-Kharusi AM, Alwaidh M, Appleton R, Baker GA, Chadwick DW, Cramp C, Cockerell OC, Cooper PN, Doughty J, Eaton B, Gamble C, Goulding PJ, Howell SJL, Hughes A, Jackson M, Jacoby A, Kellett M, Lawson GR, Leach JP, Nicolaides P, Roberts R, Shackley P, Shen J, Smith DS, Smith PEM, Tudor Smith C, Vanoli A, Williamson PR, on behalf of the SANAD Study group (2007b): The SANAD study of effectiveness of valproate, lamotrigine, or topiramate for generalized and unclassifiable epilepsy: an unblinded randomized controlled trial. Lancet 369: 1016–1026.

    Article  PubMed  CAS  Google Scholar 

  • McCorry D, Chadwick D, Marson A (2004): Current drug treatment of epilepsy in adults. Lancet Neurol 3: 729–735.

    Article  PubMed  CAS  Google Scholar 

  • Morello CM, Leckband SG, Stoner CP, Moorhouse DF, Sahagian GA (1999): Randomized double-blind study comparing the efficacy of gabapentin with amitriptyline on diabetic peripheral neuropathy pain. Arch Intern Med 159: 1931–1937.

    Article  PubMed  CAS  Google Scholar 

  • Muller M, Marson AG, Williamson PR (2006): Oxcarbazepine versus phenytoin monotherapy for epilepsy. Cochrane Database Syst Rev 19(2):CD003615.

    Google Scholar 

  • National Institute for Clinical Excellence (NICE) (2004a): The epilepsies: the diagnosis and management of the epilepsies in adults and children in primary and secondary care. Clinical Guideline 20, issue date: October 2004. Internet: www. nice.org.uk/page.aspx?o=CG020NICEguideline

    Google Scholar 

  • National Institute for Clinical Excellence (NICE) (2004b): Newer drugs for epilepsy in adults. Technology Appraisal Guidance 76. Internet: www.nice.org.uk/page. aspx?o=ta076guidance

    Google Scholar 

  • Wilby J, Kainth A, Hawkins N, Epstein D, McIntosh H, McDaid C, Mason A, Golder S, O’Meara S, Sculpher M, Drummond M, Forbes C (2005): Clinical effectiveness, tolerability and cost-effectiveness of newer drugs for epilepsy in adults: a systematic review and economic evaluation. Health Technol Assess 9: 1–157, iii–iv.

    PubMed  CAS  Google Scholar 

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Authors and Affiliations

  1. Pharmakologisches Institut der Universität Heidelberg, Im Neuenheimer Feld 366, 69120, Heidelberg

    Prof. Dr. med. Ulrich Schwabe

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  1. Prof. Dr. med. Ulrich Schwabe
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Editors and Affiliations

  1. Pharmakologisches Institut der Universität Heidelberg, Im Neuenheimer Feld 366, 69120, Heidelberg

    Ulrich Schwabe

  2. AOK Schleswig-Holstein Die Gesundheitskasse, Edisonstraße 70, 24145, Kiel

    Dieter Paffrath

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© 2008 Springer Medizin Verlag Heidelberg

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Schwabe, U. (2008). Antiepileptika. In: Schwabe, U., Paffrath, D. (eds) Arzneiverordnungs-Report 2007. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-72548-0_14

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  • DOI: https://doi.org/10.1007/978-3-540-72548-0_14

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-72547-3

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