Zusammenfassung
Das vorrangige Ziel ärztlicher Behandlung ist es, durch Wiederherstellung oder Aufrechterhaltung der Gesundheit das maximale Wohlbefinden des Patienten zu gewährleisten. Die Medizin hat in den letzten Jahren gewaltige Fortschritte gemacht, sowohl bei der Entwicklung neuer Medikamente, als auch in der Medizintechnik, die einen enormen Impuls für die Chirurgie bewirkte. Ein Weg der modernen Medizin mit dem Ziel Patienten zu helfen, ist die Organtransplantation.
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Literatur
Anonymus (1964) Hand transplanted from cadaver is reamputated. Med Trib News 5: 23–25
Beauchamp TL, Childress JF (1994) Principles of biomedical ethics, 4th edn. Oxford University Press, New York Oxford
Berger A, Brenner P, Flory P, Schaller E, Schneider W (1990) Progress in limb and digital replantation. Part B. World J Surg 14: 807–811
Berger A, Meissl G, Millesi H, Piza H (1976/1977) Replantation amputierter Gewebeteile durch micro-vaskuläre Anastomosen. Acta Chirurgica Austr 460–463
Caplan AL (1995) Organ and tissue transplants. III. Ethical and legal issues. In: Reich WT (ed) Encyclopedia of bioethics, vol 4. MacMillan Schuster, New York, pp 1888–1894
Carrell A, Guthrie CC (1906) Results of replantation of the thigh. Science 23/393: 1406–1411
Cendales L, Hardy MA (2000) Immunologic considerations in composite tissue. Microsurg 20: 412–419
Cohen LG, Bandinelli S, Findley TW, Hallett M (1991) Motor reorganization after upper limb amputation in man. A study with focal magnetic stimulation. Brain 14: 615–627
Daniel RK, Egerszegi EP, Samulack DD, Skanes SE, Dykes RW, Rennie WRJ (1986) Tissue transplants in primates for upper extremity reconstruction: a preliminary report. J Hand Surg [Am] 11: 1–8
Dettmers C, Liepert J, Adler T, Rzanny R, Rijntjes M, van Schayck R (1999) Abnormal motor cortex organization contralateral to early upper limb amputation in humans. Neurosci Lett 263: 41–44
Doolabh VB, Mackinnon SE (1999) FK506 accelerates functional recovery following nerve grafting in a rat model. Plast Reconstr Surg 103: 1928–1936
Dubernard JM, Owen E, Herzberg G (1999) Human hand allograft: report on first 6 months. Lancet 353: 1315–1320
Egerszegi EP, Samulack DD, Daniel RK (1984) Experimental models in primates for reconstructive surgery utilizing tissue transplants. Ann Plast Surg 13: 423–434
Fansa H, Keilhoff G, Altmann S, Plogmeier K, Wolf G, Schneider W (1999) The effect of the immunosuppressant FK 506 on peripheral nerve regeneration following nerve grafting. J Hand Surg [Br] 24: 38–42
Fichtner G (1968) Das verpflanzte Mohrenbein – eine Interpretation der Kosmas und Damian-Legende. Medizinhist J 3: 87–100
First MR, Peddi VR (1998) Malignancies complicating organ transplantation. Transplant Proc 30: 2768–2770
Foltys H (2000) The representation of the plegic hand in the motor cortex: a combined fMRI and TMS study. Neuroreport 11: 147–150
Francois CG, Breidenbach WC, Maldonado C et al. (2000) Hand transplantation: comparisons and observations of the first four clinical cases. Microsurgery 20: 360–371
Fritz WD, Swartz WM, Rose S (1984) Limb allografts in rats imunosuppressed with cyclosporin. Am Ann Surg 199: 211–217
Fuhr P, Cohen LG, Dang N, Findley TW, Haghighi S, Oro J (1992) Physiological analysis of motor reorganization following lower limb amputation. Electroencephalogr Clin Neurophysiol 85: 53–60
Furnas DW, Black KS, Hewitt CW (1983) Cyclosporine and long-term survival of composite tissue allografts (limb transplants) in rats (with historical notes on the role of plastic surgeons in allotransplantation). Transplant Proc 15: 3063–3069
Giraux P, Sirigu A, Schneider F, Dubernard JM (2001) Cortical reorganization in motor cortex after graft of both hands. Nat Neurosci 4: 691–692
Gold BG (1999) FK506 and the role of the immunophilin FKBP-52 in nerve regeneration. Drug Metab Rev 31: 649–663
Graham B, Adkins P, Tsai TM, Firell J, Breidenbach WC (1998) Major replantation versus revision amputation and prostethic fitting in the upper extremity: a late functional outcomes study. J Hand Surg [Am] 23: 783–791
Herndon JH (2000) Composite-tissue transplantation – a new frontier. N Engl J Med 343: 503–505.
Hettiaratchy S, Butler PEM, Lee WPA (2001) Lessons from hand transplantations. Lancet 357: 494–495
Hewitt CW, Black KS, Aguinaldo AM (1988) Pathologic alterations in the skin component of composite tissue and skin allografts treated with cyclosporine. Transplant Proc 20: 1003–1010
Hewitt CW, Black KS, Stenger JA, Go C, Achauer BM, Martin DC (1988) Comparison of kidney, composite tissue, and skin allografts survival in rats prolonged by donor blood and concomitant limited cyclosporine. Transplant Proc 20: 1110–1119
Hoepfner E (1903) Über Gefässnaht, Gefässtransplantation und Replantation von amputierten Extremitäten. Arch Klin Chir 70: 417–425
Hovius SER, Stevens HPJD, van Nierop PWM (1992) Allogeneic transplantation of the radial side of the hand in the rhesus monkey: I. Technical aspects. Plast Reconstr Surg 89: 700–709
Hovius SER (2001) Hand transplantation – an opinion. J Hand Surg [Br] 26: 519–520
Hunter JM, Mackin EJ, Callahan AD (1995) Rehabilitation of the hand: surgery and therapy. Mosby, St. Louis
Illhardt FJ (2001) Probleme in der Biographie: Identität und Organtransplantation? In: Illhardt FJ (Hrsg): Die Medizin und der Körper des Menschen. Huber, Bern, S 183–192
Jeger E (1973) Die Chirurgie der Blutgefäße und des Herzens (Reprint v. 1913). Springer, Berlin Heidelberg New York
Jones JW, Gruber SA, Barker JH, Breidenbach WC (2000) Successful hand transplantation. N Engl J Med 343: 468–473
Jones JW, Ustuner ET, Zdichavsky M et al. (1999) Long-term survival of an extremity composite tissue allograft with FK506-mycophenolate mofetil therapy. Surgey 126: 384–388
Kew JJ, Ridding MC, Rothwell JC, Passingham RE, Leigh PN, Sooriakumaran S (1994) Reorganization of cortical blood flow and transcranial magnetic stimulation maps in human subjects after upper limb amputation. J Neurophysiol 72: 2517–2524
Lanzetta M, Nolli R, Borgonovo A et al. (2001) Hand transplantation: ethics, immunosuppression and indications. J Hand Surg [Br] 26: 511–516
Lee WPA, Pan YC, Kesmarky S (1995) Experimental orthotopic transplantation of vascularized skeletal allografts: functional assessment and long-term survival. Plast Reconstr Surg 95: 336–349
Lee WPA, Rubin JP, Cober S, Lerino F, Randolph MA, Sachs DH (1998) Use of swine model in transplantation of vascularized skeletal tissue allografts. Transplant Proc 30: 2743–2745
Lee WPA, Yaremchuk MJ, Pan YC, Randolph MA, Tan CM, Weiland AJ (1991) Relative antigenicity of components of a vascularized limb allograft. Plast Reconstr Surg 87: 400–411
Lee WP, Mathes DW (1999) Hand transplantation: pertinent data and future outlook. J Hand Surg [Am] 24: 906–913
Lundborg G (1999) Hand transplantation. Editorial. Scand J Plast Reconstr Surg Hand Surg 33: 369–371
Lurija AR (1970) Die höheren kortikalen Funktionen des Menschen und ihre Störungen bei örtlichen Hirnschädigungen. Deutscher Verlag der Wissenschaft, Berlin
Lurija AR (1998) Das Gehirn in Aktion – Einführungen in die Neuropsychologie. Rowohlt, Reinbek
Margreiter R, Brandacher G, Nincovic M, Steurer W, Kreczy A, Schneeberger S (2002) A double-hand transplant can be worth the effort! Transplantation 74: 85–90
Meyer VE (1985) Hand amputations proximal but close to the wrist joint: prime candidates for reattachment (long term functional results). J Hand Surg [Am] 10: 989–992
Murray JE, Merill JP, Harrison JH (1955) Renal homotransplantation in identical twins. Surg Forum 6: 432–444
Nordzell B (1977) Reimplantation of an amputated hand. Longterm follow-up report. Scand J Plast Reconstr Surg 11: 251–253
Pascual-Leone A, Peris M, Tormos JM, Pascual AP, Catala MD (1996) Reorganization of human cortical motor output maps following traumatic forearm amputation. Neuroreport 7: 2068–2070
Perfetti C (1986) Condotte terapeutiche per la rieducazione motoria dell émiplegico. Ghedini, Milano
Perfetti C (1997) Der Hemiplegische Patient – Kognitiv Therapeutische Übungen. Pflaum, München
Piza-Katzer H (2000) Händetransplantation in Innsbruck. (Editorial) Wien Klin Wochenschr 112: 563–565
Piza-Katzer H, Ninkovic M, Pechlaner S, Gabl M, Ninkovic M, Hussl H (2002) Double hand transplantation: functional outcome after 18 months. J Hand Surg [Br] 27: 385–390
Piza-Katzer H, Hussl H, Ninkovic M et al. (2002) Beidseitige Handtransplantation. Handchir Mikrochir Plast Chir 34: 75–83
Qi HX, Stepniewska I, Kaas JH (2000) Reorganization of primary motor cortex in adult macaque monkeys with long-standing amputations. J Neurophysiol 84: 2133–2147
Russell RC, O‘Brien BMcC, Morrison WA, Pamamull G, MacLeod A (1984) The late functional results of upper limb revascularization and replantation. J Hand Surg [Am] 9: 623–633
Samulack DD, Dykes RW, Munger BL (1988) Neurophysiologic aspects of allogeneic skin and upper extremity composite tissue transplantation in primates. Transplant Proc 20: 279–284
Siegler M (1998) Ethical issues in innovative surgery: should we attempt a cadaveric hand transplantation in a human subject? Transplant Proc 30: 2779–2782
Stark GB, Swartz WM, Narayanan K (1987) Hand transplantation in baboons. Transplant Proc 19: 3968–3978
Waldmann H (1999) Transplantation tolerance-where do we stand? Nat Med 5: 1245–1248
Yuzawa K, Taniguchi H, Seino K, Otsuka M, Fukao K (1996) Topical immunosuppression in skin grafting with FK 506 ointment. Transplant Proc 28: 1387–1389
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Piza-Katzer, H. (2009). Fremdhandtransplantation. In: Berger, A., Hierner, R. (eds) Plastische Chirurgie. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-68814-3_11
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