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Funktionelle Bildgebung bei Schmerz

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Praktische Schmerztherapie

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Zusammenfassung

In den letzten Jahren ist die Anzahl funktionell-bildgebender Studien im Allgemeinen sowie bei klinischen und experimentellen Schmerzzuständen im Besonderen deutlich angewachsen. Während vor nur einem Jahrzehnt das Wissen über die Schmerzverarbeitung bzw. die funktionelle Anatomie v. a. aus molekularbiologischen und elektrophysiologischen Studien ([Penfield et al. 1937]; [Stowell et al. 1984]), Tierversuchen und Läsionsstudien stammte ([Head et al. 1911]; [Folz et al. 1962]; [Berthier et al. 1988]), sind heute mit den modernen bildgebenden Verfahren Instrumente hinzugekommen, die nichtinvasive Untersuchungen in vivo und bei vollem Bewusstsein erlauben. Es werden nun völlig neue Einblicke in die Schmerzverarbeitung, zeitliche Dynamik sowie Modulation möglich.

Vor allem zur Aufklärung der Verarbeitungsmechanismen von akuten Schmerzen konnte so bereits ein wichtiger Beitrag geleistet werden.

Eine große Aufgabe an zukünftige Forschungsprojekte stellen allerdings nach wie vor chronische Schmerzzustände bzw. die Abläufe, die zu deren Entwicklung führen, dar.

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Authors and Affiliations

  1. Neurologische Klinik und Poliklinik, Technische Universität München Klinikum rechts der Isar, Möhlstraße 28, 81675, München

    T. Sprenger, M. Valet & T. R. Tölle (Prof. Dr. Dr.)

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  1. T. Sprenger
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  2. M. Valet
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  3. T. R. Tölle
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Editors and Affiliations

  1. Sektion Neurologische Schmerzforschung und -therapie Klinik für Neurologie, Universitätsklinikum Schleswig-Holstein, Campus Kiel, Schittenhelmstraße 10, 24105, Kiel

    Ralf Baron

  2. Klinik für Anästhesie, Intensivmedizin und Schmerztherapie, Rotes Kreuz Krankenhaus, St.-Pauli-Deich 24, 28199, Bremen

    Michael Strumpf

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Sprenger, T., Valet, M., Tölle, T.R. (2007). Funktionelle Bildgebung bei Schmerz. In: Baron, R., Strumpf, M. (eds) Praktische Schmerztherapie. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-49663-2_10

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  • DOI: https://doi.org/10.1007/978-3-540-49663-2_10

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-23091-5

  • Online ISBN: 978-3-540-49663-2

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