Zusammenfassung
Wunderwaffe der Medizin, Multitalente, Alleskönner — so lauten die gebräuchlichen Umschreibungen für Stammzellen. Es besteht die Hoffnung, dass künftig Volkskrankheiten wie Morbus Parkinson, Herzinfarkt, Diabetes oder gar Alzheimer mit Stammzellen geheilt werden können. Vor sieben Jahren wurden Verfahren zur Kultur von Stammzellen aus menschlichen Embryonen etabliert. Diese öffneten völlig neue Perspektiven für Gewebezucht und Organersatz. Fast gleichzeitig haben viele Forscher in Tiermodellen Hinweise dafür gefunden, dass Stammzellen, die von erwachsenen Individuen gewonnen werden, genauso leistungsfähig sind.
Inzwischen hat sich der Rummel um eine baldige klinische Anwendung von embryonalen oder adulten Stammzellen in der regenerativen Medizin gelegt. Die Verheißungen der embryonalen Stammzellforschung lassen sich nicht aufrechterhalten. Bei Wiederholung scheiterten viele der Experimente der ersten Stunde mit adulten Stammzellen. Von den grundlegenden Steuerungsmechanismen der Stammzelleigenschaften ist noch viel zu wenig bekannt. Vom Heilungsversuch im Tiermodell bis zur Anwendung beim Menschen, wie für die Blutstammzellforschung bereits umgesetzt, wird es noch viele Jahre dauern.
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Krämer, A., Ho, A.D. (2007). Stammzellentherapie — Frischzellentherapie der Zukunft?. In: Herfarth, C. (eds) Gesundheit. Heidelberger Jahrbücher, vol 50. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-48562-9_11
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