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Abstract

Epidemiology is the science that focuses on the occurrence of disease in its broadest sense, with the fundamental aim to understand and to control its causes. This chapter deals with the conceptual building blocks of epidemiology. First we offer a model for causation, from which a variety of insights relevant to epidemiologic understanding emerge. We then discuss the basis by which we attempt to infer that an identified factor is indeed a cause of disease; the guidelines lead us through a rapid review of modern scientific philosophy. The remainder of the chapter deals with epidemiologic fundamentals of measurement, including the measurement of disease and the measurement of causal effects.

This chapter is adapted from Rothman KJ and Greenland S (eds) (1998) Modern epidemiology, 2nd edn. Lippinroth Williams Wilkins & Publishers, Philadelphia

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Rothman, K.J., Greenland, S. (2005). Basic Concepts. In: Ahrens, W., Pigeot, I. (eds) Handbook of Epidemiology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-26577-1_2

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