Abstract
Renal oxygen consumption occurs at a rate of 6–8 mL/min per 100 g. While the kidneys receive approximately 20–25% of cardiac output at rest, the kidneys use 7–10% of total oxygen uptake. The sodium-potassium ATPase pump utilizes approximately 2/3 of renal oxygen uptake. Unlike other organs and tissues in which blood flow is determined by metabolic need, blood flow to the kidney is determined by metabolic need indirectly via sodium reabsorption and effects on the glomerular filtration rate. Additionally, as renal perfusion is autoregulated, changes in perfusion altering oxygen delivery are likely restricted in the kidney; this provides a basis for the production of erythropoietin in the presence of low tissue oxygen tension.
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Elie, MC., Hwang, C., Segal, M. (2020). Renal Emergencies. In: Shiber, J., Weingart, S. (eds) Emergency Department Critical Care. Springer, Cham. https://doi.org/10.1007/978-3-030-28794-8_17
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