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Hand Function in Scleroderma

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Hand Function

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Abstract

Systemic sclerosis or scleroderma (SSc) is characterized by immunologic abnormalities, microvascular alterations, and excessive collagen production, leading to fibrosis of skin and internal organs (lungs, heart, gastrointestinal tract).

Hands are prominent targets of SSc and may be involved at different levels. Frequent signs and symptoms of the disease, such as skin and microcirculatory impairment as well as musculoskeletal involvement (of joints, tendons, and muscles), usually begin from the hands. Hand involvement evolves throughout all the course of the disease and leads to important disability in SSc.

This chapter will analyze the involvement of the hands in SSc, focusing on the causes and the kind of functional disturbances, the relation between hand impairment and other clinical parameters, hand function in different stages of the disease, and the tools to assess damage and function of the hand.

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Authors and Affiliations

  1. Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy

    Cosimo Bruni, Angela Del Rosso, Marco Matucci Cerinic & Susanna Maddali Bongi

  2. Division of Rheumatology, Azienda Ospedaliera Universitaria Careggi, Florence, Italy

    Cosimo Bruni, Angela Del Rosso, Marco Matucci Cerinic & Susanna Maddali Bongi

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  1. Cosimo Bruni
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  2. Angela Del Rosso
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  3. Marco Matucci Cerinic
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  4. Susanna Maddali Bongi
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Editors and Affiliations

  1. Department of Physical Medicine and Rehabilitation, Rheumatology Division, Marmara University Medical School, Istanbul, Turkey

    Mehmet Tuncay Duruöz

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Bruni, C., Del Rosso, A., Cerinic, M.M., Bongi, S.M. (2019). Hand Function in Scleroderma. In: Duruöz, M. (eds) Hand Function. Springer, Cham. https://doi.org/10.1007/978-3-030-17000-4_7

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  • DOI: https://doi.org/10.1007/978-3-030-17000-4_7

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