Abstract
The vertebrate eye focuses images of the environment in the plane of the retinal photoreceptors. Optimal visual function requires not only transparent dioptric media, but also that the relative sizes, shapes, and orientations of ocular tissues fall within the geometric tolerances imposed by the laws of optics. These functional requirements are met during embryonic development by the differentiation of highly specialized populations of cells from undifferentiated precursors and by the coordinated morphogenesis of the resulting tissues. Both processes are controlled to a remarkable extent by interactions which occur among the emerging tissues. Such interactions occur in an orderly, temporal sequence and help to mediate the developmental expression of one of the set of possible ocular phenotypic combinations defined by the individual genotype.
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© 1977 Plenum Press, New York
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Coulombre, A.J., Coulombre, J.L. (1977). Abnormal Organogenesis in the Eye. In: Wilson, J.G., Fraser, F.C. (eds) Handbook of Teratology. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-8933-4_13
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DOI: https://doi.org/10.1007/978-1-4615-8933-4_13
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