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Ecotoxicological Applications of Dynamic Energy Budget Theory

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Ecotoxicology Modeling

Part of the book series: Emerging Topics in Ecotoxicology ((ETEP,volume 2))

Abstract

The dynamic energy budget (DEB) theory for metabolic organisation specifies quantitatively the processes of uptake of substrate by organisms and its use for the purpose of maintenance, growth, maturation and reproduction. It applies to all organisms. Animals are special because they typically feed on other organisms. This couples the uptake of the different required substrates, and their energetics can, therefore, be captured realistically with a single reserve and a single structure compartment in biomass. Effects of chemical compounds (e.g. toxicants) are included by linking parameter values to internal concentrations. This involves a toxico-kinetic module that is linked to the DEB, in terms of uptake, elimination and (metabolic) transformation of the compounds. The core of the kinetic module is the simple one-compartment model, but extensions and modifications are required to link it to DEBs. We discuss how these extensions relate to each other and how they can be organised in a coherent framework that deals with effects of compounds with varying concentrations and with mixtures of chemicals. For the one-compartment model and its extensions, as well as for the standard DEB model for individual organisms, theory is available for the co-variation of parameter values among different applications, which facilitates model applications and extrapolations.

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Acknowledgements

This research has been supported financially by the European Union (European Commission, FP6 Contract No. 003956 and No 511237-GOCE).

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Authors and Affiliations

  1. Faculty Earth and Life Sciences, Vrije Universiteit, de Boelelaan 1085, 1081, HV, Amsterdam, The Netherlands

    Sebastiaan A. L. M. Kooijman, Jan Baas, Daniel Bontje, Mieke Broerse, Cees A. M. van Gestel & Tjalling Jager

Authors
  1. Sebastiaan A. L. M. Kooijman
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  2. Jan Baas
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  3. Daniel Bontje
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  4. Mieke Broerse
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  5. Cees A. M. van Gestel
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  6. Tjalling Jager
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Corresponding author

Correspondence to Sebastiaan A. L. M. Kooijman .

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Editors and Affiliations

  1. l'Information Scientifique (CTIS), Centre de Traitement de, chemin de la Graviere 3, Rillieux La Pape, 69140, France

    James Devillers

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Kooijman, S.A.L.M., Baas, J., Bontje, D., Broerse, M., van Gestel, C.A.M., Jager, T. (2009). Ecotoxicological Applications of Dynamic Energy Budget Theory. In: Devillers, J. (eds) Ecotoxicology Modeling. Emerging Topics in Ecotoxicology, vol 2. Springer, Boston, MA. https://doi.org/10.1007/978-1-4419-0197-2_9

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