Skip to main content

Advertisement

Log in

Anorexia nervosa

  • Review
  • Published:
European Child & Adolescent Psychiatry Aims and scope Submit manuscript

Abstract

We first discuss current diagnostic issues concerning the classification of anorexia nervosa (AN) by reference to the proposed criteria of the fifth version of the Diagnostic and Statistical Manual of Mental Disorders (DSM-5). We strongly welcome the changes in the latest revision of DSM-5 (update April 2012), which in our opinion partially solve the previously delineated classification problems. Nevertheless, we still miss a standard or reference(s) for the weight criterion including the delineation between a healthy and unhealthy underweight, a better operationalization of observable behaviors including symptoms of disordered eating, readily accessible cognitions and a better allowance for cross-cultural aspects in the proposed DSM-5 classification of AN. In the second part, we review the treatment recommendations of the NICE guidelines for AN, which overall are characterized by a lack of evidence. Nevertheless, NICE recommended an outpatient treatment setting based on one randomized controlled trial with many methodological limitations. A review of the current literature shows that (a) the optimal treatment setting (inpatient vs. outpatient treatment) still is a subject of debate, and (b) the evaluation of treatment costs in AN plays an important role within this discussion. In contrast to the German Guidelines for the Treatment of Eating Disorders, NICE does not offer any specific criteria for the clinician with regard to determining the adequate treatment setting.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. Hebebrand J, Casper R, Treasure J, Schweiger U (2004) The need to revise the diagnostic criteria for anorexia nervosa. J Neural Transm 111:827–840

    Article  PubMed  CAS  Google Scholar 

  2. Hebebrand J, Bulik CM (2011) Critical appraisal of the provisional DSM-5 criteria for anorexia nervosa and an alternative proposal. Int J Eat Disord 44(8):665–678

    Article  PubMed  Google Scholar 

  3. Uher R, Rutter M (2012) Classification of feeding and eating disorders: review of evidence and proposals for ICD-11. World Psychiatry 11(2):80–92

    Article  PubMed  Google Scholar 

  4. Heymsfield SB, Darby PC, Muhlheim LS, Gallagher D, Wolper C, Allison DB (1995) The calorie: myth, measurement, and reality. Am J Clin Nutr 62:1034S–1041S

    PubMed  CAS  Google Scholar 

  5. Becker AE, Eddy KT, Perloe A (2009) Clarifying criteria for cognitive signs and symptoms for eating disorders in DSM-V. Int J Eat Disord 42:611–619

    Article  PubMed  Google Scholar 

  6. Bravender T, Bryant-Waugh R, Herzog D, Katzman D, Kreipe RD, Lask B, Le Grange D, Lock J, Loeb K, Madden S, Nicholls D, O’Toole J, Pinhas L, Rome E, Sokol-Burger M, Wallen U, Zucker N (2007) Workgroup for Classification of Eating Disorders in Children and Adolescents. Classification of child and adolescent eating disturbances. Workgroup for Classification of Eating Disorders in Children and Adolescents (WCEDCA). Int J Eat Disord 40:117–122

    Article  Google Scholar 

  7. Lee S, Ng KL, Kwok K, Fung C (2010) The changing profile of eating disorders at a tertiary psychiatric clinic in Hong Kong (1987–2007). Int J Eat Disord 43(4):307–314

    PubMed  Google Scholar 

  8. Pinheiro A, Thornton L, Plotonicov K, Tozzi T, Klump K, Berrettini W et al (2007) Patterns of menstrual disturbance in eating disorders. Int J Eat Disord 40:424–434

    Article  Google Scholar 

  9. Föcker M, Timmesfeld N, Scherag S, Bühren K, Langkamp M, Dempfle A, Sheridan EM, de Zwaan M, Fleischhaker C, Herzog W, Egberts K, Zipfel S, Herpertz-Dahlmann B, Hebebrand J (2011) Screening for anorexia nervosa via measurement of serum leptin levels. J Neural Transm 118(4):571–578

    Article  PubMed  Google Scholar 

  10. Eddy KT, Dorer DJ, Franko DL, Tahilani K, Thompson-Brenner H, Herzog DB (2008) Diagnostic crossover in anorexia nervosa and bulimia nervosa: implications for DSM-V. Am J Psychiatry 165:245–250

    Article  PubMed  Google Scholar 

  11. Peat C, Mitchell JE, Hoek HW, Wonderlich SA (2009) Validity and utility of subtyping anorexia nervosa. Int J Eat Disord 42(7):590–594

    Article  PubMed  Google Scholar 

  12. Peebles R, Hardy KK, Wilson JL, Lock JD (2010) Are diagnostic criteria for eating disorders markers of medical severity? Pediatrics 125(5):e1193–e1201

    Article  PubMed  Google Scholar 

  13. Le Grange D, Swanson SA, Crow SJ, Merikangas KR (2012) Eating disorder not otherwise specified presentation in the US population. Int J Eat Disord 45(5):711–718

    Article  PubMed  Google Scholar 

  14. Keel PK, Brown TA, Holm-Denoma J, Bodell LP (2011) Comparison of DSM-IV versus proposed DSM-5 diagnostic criteria for eating disorders: reduction of eating disorder not otherwise specified and validity. Int J Eat Disord 44(6):553–560

    Article  PubMed  Google Scholar 

  15. Birgegård A, Norring C, Clinton D (2012) DSM-IV versus DSM-5: implementation of proposed DSM-5 criteria in a large naturalistic database. Int J Eat Disord 45(3):353–361

    Article  PubMed  Google Scholar 

  16. NICE (2004) Available from: http://www.nice.org.uk/nicemedia/live/10932/29218/29218.pdf. Accessed 9 Nov 2004

  17. Wilson GT, Shafran R (2005) Eating disorders guidelines from NICE. Lancet 365(9453):79–81

    Article  PubMed  Google Scholar 

  18. Hartmann A, Weber S, Herpertz S, Zeeck A (2011) Psychological treatment for anorexia nervosa: a meta-analysis of standardized mean change. Psychother Psychosom 80:216–226

    Article  PubMed  Google Scholar 

  19. Wilson GT, Grilo CM, Vitousek KM (2007) Psychological treatment of eating disorders. Am Psychol 62(3):199–216

    Article  PubMed  Google Scholar 

  20. Krauth C, Buser K, Vogel H (2002) How high are the costs of eating disorders—anorexia nervosa and bulimia nervosa—for German society? Eur J Health Econ 3(4):244–250

    Article  PubMed  CAS  Google Scholar 

  21. Steinhausen HC (2002) The outcome of anorexia nervosa in the 20th century. Am J Psychiatry 159(8):1284–1293

    Article  PubMed  Google Scholar 

  22. German S3 Guideline on the Diagnosis and Treatment of Eating Disorders, 2011; Available from: http://www.awmf.org/leitlinien/detail/ll/051-026.html. Accessed 12 Dec 2010

  23. Crisp AH, Norton K, Gowers S, Halek C, Bowyer C, Yeldham D, Levett G, Bhat A (1991) A controlled study of the effect of therapies aimed at adolescent and family psychopathology in anorexia nervosa. Br J Psychiatry 159:325–333

    Article  PubMed  CAS  Google Scholar 

  24. Gowers S, Norton K, Halek C, Crisp AH (1994) Outcome of outpatient psychotherapy in a random allocation treatment study of anorexia nervosa. Int J Eat Disord 15(2):165–177

    Article  PubMed  CAS  Google Scholar 

  25. Meads C, Gold L, Burls A (2001) How effective is outpatient care compared to inpatient care for the treatment of anorexia nervosa? A systematic review. Eur Eat Disord Rev 9:229–241

    Article  Google Scholar 

  26. Bowers WA, Andersen AE (1994) Inpatient treatment of anorexia nervosa: review and recommendations. Harv Rev Psychiatry 2:193–203

    Article  PubMed  CAS  Google Scholar 

  27. Zipfel S, Reas DL, Thornton C, Olmsted MP, Williamson DA, Gerlinghoff M, Herzog W, Beumont PJ (2002) Day hospitalization programs for eating disorders: a systematic review of the literature. Int J Eat Disord 31:105–117

    Article  PubMed  Google Scholar 

  28. Gowers SG, Clark AF, Roberts C, Byford S, Barrett B, Griffiths A, Edwards V, Bryan C, Smethurst N, Rowlands L, Roots P (2010) A randomised controlled multicentre trial of treatments for adolescent anorexia nervosa including assessment of cost-effectiveness and patient acceptability—the TOuCAN trial. Health Technol Assess 14(15):1–98

    PubMed  CAS  Google Scholar 

  29. Hoek HW (2006) Incidence, prevalence and mortality of anorexia nervosa and other eating disorders. Curr Opin Psychiatry 19(4):389–394

    Article  PubMed  Google Scholar 

  30. Striegel-Moore RH, Leslie D, Petrill SA, Garvin V, Rosenheck RA (2000) One-year use and cost of inpatient and outpatient services among female and male patients with an eating disorder: evidence from a national database of health insurance claims. Int J Eat Disord 27(4):381–389

    Article  PubMed  CAS  Google Scholar 

  31. Stuhldreher N, Konnopka A, Wild B, Herzog W, Zipfel S, Lowe B, Konig HH (2012) Cost-of-illness studies and cost-effectiveness analyses in eating disorders: a systematic review. Int J Eat Disord 45:476–491

    Article  PubMed  Google Scholar 

Download references

Conflict of interest

On behalf of all authors, the corresponding author states that there are no conflicts of interest. This article is part of the supplement “The Future of Child and Adolescent Psychiatry and Psychology: The Impact of DSM 5 and of Guidelines for Assessment and Treatment”. This supplement was not sponsored by outside commercial interests.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Johannes Hebebrand.

Additional information

M. Föcker and S. Knoll contributed equally.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Föcker, M., Knoll, S. & Hebebrand, J. Anorexia nervosa. Eur Child Adolesc Psychiatry 22 (Suppl 1), 29–35 (2013). https://doi.org/10.1007/s00787-012-0358-6

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00787-012-0358-6

Keywords

Navigation