Exp Clin Endocrinol Diabetes 2007; 115(9): 619-621
DOI: 10.1055/s-2007-985358
Letter to the Editor

© J. A. Barth Verlag in Georg Thieme Verlag KG · Stuttgart · New York

Spontaneous Remission of Primary Hyperparathyroidism

S. Schinner 1 , R. Fritzen 2 , M. Schott 1 , H. S. Willenberg 1 , W. A. Scherbaum 1
  • 1Department of Endocrinology, Diabetes and Rheumatology, University Hospital Duesseldorf, Duesseldorf, Germany
  • 2Mathias Spital Rheine, Rheine, Germany
Further Information

Publication History

received 18.03.2007 first decision 12.04.2007

accepted 16.07.2007

Publication Date:
18 October 2007 (online)

Abstract

The diagnosis of primary hyperparathyroidism (pHPT) is characterized by the constellation of elevated plasma serum calcium levels and low serum anorganic phosphate associated with inadequately high blood concentrations of parathyroid hormone (PTH). Parathyroid adenomas are the main reason for this disorder and can frequently be detected by ultrasound examination. Surgical removal of the parathyroid adenoma is recommended in the case of primary hyperpara­thyroidism complicated by osteoporosis, hyper-calciuria, nephrolithiasis, or impaired renal function. Here we present the case of a 68-year-old man with spontaneous remission of primary hyperparathyroidism two years after the diagnosis was established. The remission was documented by laboratory findings (normalisation of serum calcium and PTH levels) and by ultrasound examination that showed the disappearance of a cervical mass suggesting a parathyroid adenoma.

References

  • 1 Bilezikian JP, Potts  Jr JT, Fuleihan G, Kleerekoper M, Neer R, Peacock M, Rastad J, Silverberg SJ, Udelsman R, Wells  Jr SA. Summary statement from a workshop on asymptomatic primary hyperparathyroidism: a perspective for the 21st century.  J. Bone Miner. Res. 2002;  17 ((Suppl 2)) 2-11
  • 2 Kovacs KA, Gay JD. Remission of primary hyperparathyroidism due to spontaneous infarction of a parathyroid adenoma. Case report and review of the literature.  Medicine (Baltimore). 1998;  77 398-402
  • 3 Lucas   Jr DG, Lockett MA, Cole DJ. Spontaneous infarction of a parathyroid adenoma: two case reports and review of the literature.  Am. Surg. 2002;  68 173-176
  • 4 Norris EH. Primary Hyperparathyroidism.  Arch Pathol. 1946;  42 261-273

Correspondence

Dr. S. Schinner

Department of Endocrinology, Diabetes and Rheumatology

University Hospital Duesseldorf

Moorenstr 5

40225 Duesseldorf

Germany

Email: sven.schinner@uni-duesseldorf.de

    >