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DOI: 10.1055/s-2007-985358
© J. A. Barth Verlag in Georg Thieme Verlag KG · Stuttgart · New York
Spontaneous Remission of Primary Hyperparathyroidism
Publication History
received 18.03.2007
first decision 12.04.2007
accepted 16.07.2007
Publication Date:
18 October 2007 (online)
Abstract
The diagnosis of primary hyperparathyroidism (pHPT) is characterized by the constellation of elevated plasma serum calcium levels and low serum anorganic phosphate associated with inadequately high blood concentrations of parathyroid hormone (PTH). Parathyroid adenomas are the main reason for this disorder and can frequently be detected by ultrasound examination. Surgical removal of the parathyroid adenoma is recommended in the case of primary hyperparaÂthyroidism complicated by osteoporosis, hyper-calciuria, nephrolithiasis, or impaired renal function. Here we present the case of a 68-year-old man with spontaneous remission of primary hyperparathyroidism two years after the diagnosis was established. The remission was documented by laboratory findings (normalisation of serum calcium and PTH levels) and by ultrasound examination that showed the disappearance of a cervical mass suggesting a parathyroid adenoma.
Key words
thyroid - primary hyperparathyroidism - parathyroid hormone - hypercalcemia
References
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- 2 Kovacs KA, Gay JD. Remission of primary hyperparathyroidism due to spontaneous infarction of a parathyroid adenoma. Case report and review of the literature. Medicine (Baltimore). 1998; 77 398-402
- 3 Lucas Jr DG, Lockett MA, Cole DJ. Spontaneous infarction of a parathyroid adenoma: two case reports and review of the literature. Am. Surg. 2002; 68 173-176
- 4 Norris EH. Primary Hyperparathyroidism. Arch Pathol. 1946; 42 261-273
Correspondence
Dr. S. Schinner
Department of Endocrinology, Diabetes and Rheumatology
University Hospital Duesseldorf
Moorenstr 5
40225 Duesseldorf
Germany
Email: sven.schinner@uni-duesseldorf.de