Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology
Oral MedicineCharacteristics of oral and paraoral malignant lymphoma: A population-based review of 361 cases*
Section snippets
Material and methods
Patients diagnosed with lymphoma of the oral region, including the pharynx and salivary glands, were identified from the Tumor Registry and the computer files of the British Columbia Cancer Agency between the beginning of January 1969 and the end of February 1998. The Tumor Registry records all malignant diagnoses for the population of British Columbia. Documentation in the Registry is based on the first malignant diagnosis. Complete records were available beginning in January 1969.
The criteria
Results
Between January 1, 1969, and February 28, 1998, the total number of cases of malignant disease in British Columbia was 362,531. Of the total cases of cancer, 16,598, or 4.6%, were cases of head and neck cancer. The total number of cases of malignant lymphoma (ML) diagnosed during those years was 14,452 cases, which represented 4% of the total malignancies.
Intraoral malignancies were diagnosed in 10,190 cases between 1969 and 1998, which represent 61.39% of all head and neck cases. Of the head
Discussion
The lymphomas are a group of neoplasms arising in the reticuloendothelial and lymphatic system. The lymphomas are the seventh most common cancers in the United Sates, but because of a younger average age of diagnosis, lead to more years of potential life lost than many adult cancers.14, 15, 16 The cell of origin of Hodgkin's disease appears to be from the monocyte-histiocyte series manifesting in the disease as Reed-Sternberg cells. Hodgkin's disease accounts for approximately 14% of all ML.14,
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Reprint requests: Joel Epstein, Department of Dentistry, BC Cancer Agency, 600 West 10th Ave, Vancouver, BC, V5Z 4E6, [email protected]
- a
Medical/Dental Staff, British Columbia Cancer Agency, Vancouver, British Columbia, Canada; Head, Department of Dentistry, Vancouver Hospital and Health Sciences Centre; Professor, University of British Columbia, Vancouver, BC, Canada; Research Associate Professor, University of Washington, Seattle.
- b
Research Assistant, Department of Dentistry, Vancouver Hospital and Health Sciences Center, Vancouver, BC, Canada.
- c
Research Scientist, Department of Epidemiology and Biometry, British Columbia Cancer Agency, Vancouver, BC, Canada.
- d
Professor, The Maurice and Gabriela Goldschleger School of Dental Medicine, Tel Aviv University, Israel