Society of University SurgeonsImpact of donor cardiac arrest on heart transplantation
Section snippets
Methods
The Institutional Review Board at Duke University Medical Center approved this study. Individual patient consent was deemed unnecessary.
Results
A total of 21,383 heart transplant recipients were included in the analysis. Of these, 930 (4.3%) had received their allografts from donors who had undergone cardiac arrest (Donor Arrest), and 20,453 came from donors without histories of cardiac arrest (No Arrest). Patients excluded from the final study population are summarized in Figure 1. The median follow-up time was 3.7 years. The Donor Arrest group had a greater incidence of sex mismatch (31% vs 27.6%, P = .02); race mismatch (46.5% vs
Discussion
The purpose of this study was to determine the impact of donor cardiac arrest on both short- and long-term outcomes after orthotopic heart transplantation. There were no differences in either 30-day mortality or overall survival between recipients of hearts with or without histories of donor cardiac arrest. Additionally, we demonstrated that increasing duration of arrest time was significantly associated with decreasing survival.
Current outcomes after heart transplantation are excellent and
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