Clinical ResearchAcute Coronary SyndromeA Randomized Comparison of High Clopidogrel Loading Doses in Patients With Non–ST-Segment Elevation Acute Coronary Syndromes: The ALBION (Assessment of the Best Loading Dose of Clopidogrel to Blunt Platelet Activation, Inflammation and Ongoing Necrosis) Trial
Acute Coronary Syndrome
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Abbreviations and Acronyms
ADP
adenosine diphosphate
ASA
acetylsalicylic acid
AUC
area under the inhibition of platelet aggregation curve
GP
glycoprotein
IPA
inhibition of platelet aggregation
LD
loading dose
LMWH
low molecular weight heparin
MACE
major adverse cardiac events
MFI
median fluorescence intensity
NSTE-ACS
non–ST-segment elevation acute coronary syndrome
PA
platelet aggregation
PAI
plasminogen activator inhibitor
PCI
percutaneous coronary intervention
PGE1
prostaglandin E1
sCD40L
soluble CD40 ligand
VASP
vasodilator-stimulated phosphoprotein
vWF Ag
von Willebrand factor antigen
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This study was supported by a grant from Sanofi-Aventis and Bristol-Myers Squibb. Some conflict of interest with Sanofi Aventis and BMS exists.
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Dr. Montalescot, Ms. Bal-dit-SoAllier, Dr. Steg, and Dr. Drouet declare that they have been consultants for and/or have received research grants from Sanofi-Aventis.
Copyright © 2006 American College of Cardiology Foundation. Published by Elsevier Inc. All rights reserved.