Coronary artery diseaseEffect of Anemia in High-Risk Groups of Patients With Acute Myocardial Infarction Treated With Percutaneous Coronary Intervention
Section snippets
Methods
The study group consisted of 1,497 consecutive patients, who were admitted to our department from September 2004 to December 2007 with AMI and treated in the acute phase with PCI. The clinical criteria of AMI evaluated on admission were chest pain persisting for >20 minutes, ST-segment elevation of ≥0.1 mV in 2 continuous electrocardiographic leads, or non–ST-segment elevation and enzymatic confirmation of AMI. Patients were mainly admitted from referral hospitals. All patients were included in
Results
The patients with anemia were older, more likely to be women, and to have a lower body mass index and greater baseline serum creatinine. They were more likely to have history of myocardial infarction, PCI, and diabetes and were less likely to have history of smoking. They presented with a higher Killip class and longer lasting symptoms of AMI before admission. The clinical characteristics of the study population are listed in Table 1.
Patients with anemia had more advanced coronary artery
Discussion
Most previous studies have demonstrated an association between anemia and MACE.15, 18, 19, 20 However, most of these studies concerned patients with stable angina, which might explain the low in-hospital cardiac mortality.15, 18 Reinecke et al18 examined the relation between the hemoglobin concentration and in-hospital and long-term survival after PCI in 689 male patients. In their study, the in-hospital mortality rate was very low (0% to 0.7%) and was not significantly influenced by the
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