Carvedilol affects the physiological and behavioral response to smoked cocaine in humans
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Drug addiction co-morbidity with alcohol: Neurobiological insights
2021, International Review of NeurobiologyComparison of Frequency of Cardiovascular Events and Mortality in Patients With Heart Failure Using Versus Not Using Cocaine
2017, American Journal of CardiologyCarvedilol does not reduce cocaine use in methadone-maintained cocaine users
2017, Journal of Substance Abuse TreatmentCitation Excerpt :CAR is an alpha1- and beta-adrenergic receptor blocker used primarily for the treatment of congestive heart failure and hypertension (Frishman, 1998). CAR may also have utility for the treatment of cocaine addiction as indicated by a human laboratory study in which CAR attenuated both cocaine-induced blood pressure and heart rate increases, as well as cocaine self-administration behavior (Sofuoglu, Brown, Babb, Pentel, & Hatsukami, 2000). In addition, CAR has been administered to cocaine users for the treatment of cardiac disorders including myocardial infarction, heart failure and cocaine-induced cardiac toxicity (Littmann, Narveson, Fesel, & Marconi, 2013; Ocal et al., 2015; Self, Rogers, Mancell, & Soberman, 2011).
Labetalol and cardiovascular consequences of cocaine use
2016, Trends in Cardiovascular MedicineThe alpha-1 adrenergic antagonist doxazosin for treatment of cocaine dependence: A pilot study
2013, Drug and Alcohol Dependence
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