Case reportMassive propranolol overdose poorly responsive to pharmacologic therapy: Use of the intra-aortic balloon pump
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Overdose of cardiotoxic drugs
2018, Cardiac Intensive CareEuropean Resuscitation Council Guidelines for Resuscitation 2015. Section 4. Cardiac arrest in special circumstances
2015, ResuscitationCitation Excerpt :Evidence for treatment is based on case reports and animal studies. Improvement has been reported with glucagon (50–150 mcg kg−1),357–370 high-dose insulin and glucose,371–373 lipid emulsions,374–377 phosphodiesterase inhibitors,378,379 extracorporeal and intra-aortic balloon pump support,380–382 and calcium salts.258,383 Calcium channel blocker overdose is emerging as a common cause of prescription drug poisoning deaths.384,385
Focused Echocardiography during Glucagon Administration to Diagnose Beta-Blocker-Induced Cardiomyopathy
2015, Journal of Cardiothoracic and Vascular AnesthesiaCitation Excerpt :Cardiac pacing may be required with severe bradycardia although, even if capture is established, there may not be a compensatory rise in blood pressure because of lack of intracellular calcium.22 Additionally, intra-aortic balloon pumps23 and extracorporeal membrane oxygenation1 have been utilized with success after glucagon when other less-invasive therapies and interventions have failed. In a severe case, a patient ingested 2 g of propranolol and required extracorporeal membrane oxygenation support and recovered neurologically intact.1
Cardiovascular Toxicity of Cardiovascular Drugs
2014, Heart and ToxinsEuropean Resuscitation Council Guidelines for Resuscitation 2010 Section 8. Cardiac arrest in special circumstances: Electrolyte abnormalities, poisoning, drowning, accidental hypothermia, hyperthermia, asthma, anaphylaxis, cardiac surgery, trauma, pregnancy, electrocution
2010, ResuscitationCitation Excerpt :Evidence for treatment is based on case reports and animal studies. Improvement has been reported with glucagon (50–150 μg kg−1),108–121 high-dose insulin and glucose,122–124 phosphodiesterase inhibitors,125,126 calcium salts,127 extracorporeal and intra-aortic balloon pump support,128–130 and calcium salts.131 Calcium channel blocker overdose is emerging as a common cause of prescription drug poisoning deaths.22,132
Part 8: Advanced life support: 2010 International consensus on cardiopulmonary resuscitation and emergency cardiovascular care science with treatment recommendations
2010, ResuscitationCitation Excerpt :A single human case report documented that high-dose insulin (10 U kg−1 h−1 IV), given with glucose supplementation and electrolyte monitoring, was followed by improved haemodynamic stability and survival to hospital discharge in the setting of severe cardiovascular toxicity associated with β-blocker toxicity (LOE 5).541 Case reports described the use of phosphodiesterase inhibitors (LOE 5),542,543 calcium salts (LOE 4),544 extracorporeal support (LOE 5),545 intraaortic balloon pumps (LOE 4),546 and ECMO (LOE 4).547 Animal studies supported the use of calcium salts (LOE 5)548 and the phosphodiesterase inhibitor amrinone (LOE 5).549