Original contribution
Haloperidol for sedation of disruptive emergency patients

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Agitated, threatening, or violent behavior often jeopardizes the patient with self-inflicted injury or delays medical evaluation and treatment. Patient cooperation with therapy can be achieved using haloperidol by the IM, IV, or oral route. The safety and efficacy of haloperidol in the emergency department setting was examined. Haloperidol was administered to 136 patients to control behavior. Eighty-eight received the drug in the ED; 18 of these 88 were critical patients receiving the drug during resuscitation. Forty-eight of the 136 were crisis intervention center patients. Ninety patients were acutely intoxicated with ethanol. Twenty-three patients had head trauma; 20 of these also were inebriated. Various other drugs were responsible for the behavior of 15 patients. Acute psychosis was involved in 40 cases. Thirty-one patients were thought to have a personality disorder. The route of administration of haloperidol was intramuscular in 110, IV in 19, and oral in seven patients. Disruptive behavior was alleviated within 30 minutes in 113 of 136 (83%) patients. Effect was judged suboptimal in 20 of 136 (15%), and no effect was noted in three of 136 (2%) patients. Four complications (3%) were noted, three minor and one more serious episode of hypotension in a critical patient. Haloperidol is a safe and efficacious drug for use with disruptive patients in the emergency setting. It is a useful tool for management of agitation of diverse etiologies.

References (15)

  • DudleyDL et al.

    Emergency use of intravenous haloperidol

    General Hosp Psychiatr

    (1979)
  • MartinML et al.

    Neuroleptic malignant syndrome

    Ann Emerg Med

    (1985)
  • IrwinGE et al.

    Neuroleptic malignant syndrome

    Am J Emerg Med

    (1984)
  • AydFJ

    Haloperidol: Twenty years' clinical experience

    J Clin Psychiatry

    (1978)
  • AndersonWH et al.

    Strategies for the treatment of acute psychosis

    JAMA

    (1974)
  • BenforadoJM et al.

    The use of haloperidol to control agitation/violence during admission to an alcohol detoxification center

    Curr Alcohol

    (1979)
  • LenehanGP et al.

    Use of haloperidol in the management of agitated or violent, alcohol-intoxicated patients in the emergency department: A pilot study

    J Emerg Nurs

    (1985)
There are more references available in the full text version of this article.

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Presented at the University Association for Emergency Medicine Annual Meeting, Portland, Oregon, May 1986.

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