Original contributionExpired PCO2 as a prognostic indicator of successful resuscitation from cardiac arrest
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Cited by (125)
End-tidal CO<inf>2</inf>-guided automated robot CPR system in the pig. Preliminary communication
2018, ResuscitationCitation Excerpt :In 1985, Weil et al reported that end-tidal CO2 reflected cardiac output and pulmonary blood flow during CPR in a porcine model of cardiac arrest [9]. After that, several researchers demonstrated that in both animals and human beings, the measurement of end-tidal CO2 during CPR could be used as a reliable noninvasive indicator of successful resuscitation [10–13]. Therefore, end-tidal CO2 is important for monitoring the quality of chest compressions during CPR [14,15].
Physiologic monitoring of CPR quality during adult cardiac arrest: A propensity-matched cohort study
2016, ResuscitationCitation Excerpt :Therefore, this study takes an important first step by providing prospectively collected human data and associating clinician-reported intra-arrest physiologic monitoring of CPR quality with superior clinical outcomes. Numerous experimental models have demonstrated that ETCO2 correlates well with pulmonary blood flow, cardiac output, and resuscitation success.17,26–28 Clinical data supporting ETCO2 monitoring during CPR dates back to the 1970s when Kalenda described using ETCO2 levels to monitor for rescuer fatigue (declining ETCO2) and for ROSC (sudden rise in ETCO2).29
Quantitative relationship between end-tidal carbon dioxide and CPR quality during both in-hospital and out-of-hospital cardiac arrest
2015, ResuscitationCitation Excerpt :In the 2010 consensus resuscitation guidelines, the use of waveform capnography during CPR is encouraged to confirm endotracheal tube placement; in addition, the guidelines state “it is reasonable to consider using waveform capnography in intubated patients to monitor CPR quality [and] optimize chest compressions …”.17 This is largely based on laboratory investigations of cardiac arrest, demonstrating that ETCO2 correlates with both coronary and cerebral perfusion pressures during CPR delivery.18,19 While a small clinical study also suggested that ETCO2 and arterial pressure rise with increasing chest compression force,8 few data exist describing the clinical relationship of ETCO2 and CPR quality during actual IHCA or OHCA resuscitation care, including such metrics as chest compression rate and depth.
An optimal closed-loop control strategy for mechanical chest compression devices: A trade-off between the risk of chest injury and the benefit of enhanced blood flow
2012, Computer Methods and Programs in Biomedicine"Putting it all together" to improve resuscitation quality
2012, Emergency Medicine Clinics of North AmericaCitation Excerpt :In these situations, continuous end-tidal monitoring CO2 (ie, capnography) can be used as an alternative to monitor CPR quality. In numerous experimental models, noninvasive end-tidal CO2 correlates well with cardiac output, MPP, and resuscitation success.85–89 Furthermore, the utility of end-tidal CO2 monitoring during clinical investigations is not a new discovery and has been described since the 1970s when Kalenda90 described three patients who were monitored for expired CO2 during cardiac arrest.
Presented at the Scientific Assembly of the American College of Emergency Physicians in Dallas, Texas, October 1984.
This study was supported by a grant-inaid from the American Heart Association, Arizona Affiliate.