Brief reportComparison of intravenous and intranasal administration of epinephrine during CPR in a canine model
References (10)
- et al.
Endotracheal versus IV epinephrine during electromechanical dissociation with CPR in dogs
Ann Emerg Med
(1985) - et al.
Dose-related response of centrally administered epinephrine on the change in aortic diastolic pressure during closed-chest massage in dogs
Ann Emerg Med
(1985) - et al.
Comparative effect of graded doses of epinephrine on regional brain-blood flow during CPR in a swine model
Ann Emerg Med
(1986) Standards and guidelines for cardiopulmonary resuscitation (CPR) and emergency cardiac care (ECC)
JAMA
(1986)- et al.
Intranasal administration of nitroglycerin
Anesthesiology
(1981)
Cited by (30)
Targeted drug delivery to the inferior meatus cavity of the nasal airway using a nasal spray device with angled tip
2022, Computer Methods and Programs in BiomedicineEffects of nasal drug delivery device and its orientation on sprayed particle deposition in a realistic human nasal cavity
2016, Computers in Biology and MedicineCitation Excerpt :The nasal route for therapeutic agent delivery is an attractive proposition due to the possibility of obtaining a systemic and local response, especially when rapid absorption and effect are desired [5,33]. Nasal sprays are seen as a more efficient way compared with injection or pills to transport drugs with potential use in bypassing the blood-brain barrier [2]. Due to the filtration effect of anterior nostril, majority of sprayed droplets deposits in the anterior nasal cavity [1,14,21,31].
Clinical evaluation of intranasal benzodiazepines, α<inf>2</inf>- agonists and their antagonists in canaries
2006, Veterinary Anaesthesia and AnalgesiaCitation Excerpt :The nasal mucosa represents a highly permeable route of drug absorption, and a number of drugs are absorbed systemically at this site. Intranasal administration of epinephrine during cardiac arrest and cardiopulmonary resuscitation has been attempted in dogs (Bleske et al. 1992) while IN sedatives and analgesics have been used in human paediatric patients (Wilton et al. 1988; Rey et al. 1991; Karl et al. 1992; Kendall et al. 2001). The attainment of significant plasma midazolam concentrations occurs as early as 10 minutes after IN administration in human beings (Walbergh et al. 1991).
Drugs in modern resuscitation
1997, British Journal of Anaesthesia
Presented at the American College of Clinical Pharmacy Annual Meeting in Minneapolis, Minnesota, August 1991.