Clinical StudiesMajor bleeding after hospitalization for deep-venous thrombosis☆
Section snippets
Discharge cohort
The Office of Statewide Health Planning and Development requires that all non-federal, licensed hospitals submit information about each inpatient after discharge, including demographic data, the principal diagnosis (“the condition chiefly responsible for occasioning the admission”), up to 24 secondary diagnoses, a principal procedure, and up to 20 secondary procedures. All procedures and diagnoses are coded using the International Classification of Diseases, 9th Revision, Clinical Modification
Results
Between January 1, 1992, and September 30, 1994, exactly 22,000 patients with venous thrombosis met the entry criteria (Figure 1). The demographic and clinical characteristics of these patients are included in Table 1. During the initial hospitalization, 646 (2.9%) of the 22,000 patients bled, 29 (4.4%) of whom died. Because many of the patients who bled during the initial hospitalization may not have been treated as outpatients with warfarin, they were not included in the analysis of our
Discussion
The decision to begin anticoagulation therapy in a patient with venous thrombosis requires weighing the risk of major bleeding against the benefits of treatment (19). That decision is usually not difficult, because the risk of fatal pulmonary embolism is high if treatment is withheld (20). Nevertheless, there are certain clinical situations, such as calf-vein thrombosis, when anticoagulant treatment is not mandatory, and it is acceptable to follow these patients using serial venous ultrasound
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Acute Pulmonary Embolism
2021, Encyclopedia of Respiratory Medicine, Second EditionSplanchnic vein thrombosis predicts worse survival in patients with advanced pancreatic cancer
2020, Thrombosis ResearchA high Gas6 level in plasma predicts venous thromboembolism recurrence, major bleeding and mortality in the elderly: a prospective multicenter cohort study
2019, Journal of Thrombosis and Haemostasis
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Dr. Beyth is a recipient of a National Institute of Aging Clinical Investigator Award (K08-AG00712-01A).