Fighting the ventilator — are fast rates an effective alternative to paralysis?
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Cited by (42)
Patient-Ventilator Interaction
2018, The Newborn Lung: Neonatology Questions and Controversies, Third EditionMechanical ventilation-induced reverse-triggered breaths: A frequently unrecognized form of neuromechanical coupling
2013, ChestCitation Excerpt :How the physician can abolish such an undesirable effect by modifying the ventilator settings cannot be answered based solely on our results. Previous studies have shown that entrainment is affected by changes in RRvent and Vt.3, 17 In newborn infants, 1:1 entrainment has been achieved at ventilator rates close to spontaneous breathing.17,23–25 In anesthetized humans, 1:1 entrainment was maintained at a range of machine inflations ± 40% of the subject's spontaneous breathing frequencies and at mechanical Vt between 40% and 140% of the patient's spontaneous Vt.3 In vagally intact animals and humans, when the machine frequency was reduced to below the spontaneous breathing rate, neural efforts preceded the onset of mechanical inflations and the spontaneous rate decreased.3, 5, 7
Recommendations for respiratory support in the newborn
2012, Anales de PediatriaPatient-Ventilator Interaction
2012, The Newborn Lung: Neonatology Questions and Controversies Expert ConsultPatient-Ventilator Interaction
2012, The Newborn LungProportional Assist Ventilation and Neurally Adjusted Ventilatory Assist-Better Approaches to Patient Ventilator Synchrony?
2008, Clinics in Chest MedicineCitation Excerpt :The underlying physiologic mechanisms of entrainment are becoming better understood and may suggest a clinical value where the patient is synchronized to the ventilator and not the other way around, as is the case with synchronized modes of mechanical ventilation [61]. However, in the event that entrainment is unsuccessful [62], there is still a demand for systems to monitor the ventilator-patient interaction. Pneumatic off-cycling algorithms are designed to sense a decrease in flow relative to the peak inspiratory flow.